Analysis of T helper cell responses during infection with Leishmania amazonensis

American Journal of Tropical Medicine and Hygiene

Volumn 66, Issue 4, 2002, Pages 338-345

  Ji, Jiaxiang ^a   Sun, Jiaren ^a   Qi, Hai ^a   Soong, Lynn ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 4; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE PREDISPOSITION; FEMALE; HELPER CELL; LEISHMANIA; LEISHMANIASIS; LYMPHOCYTE SUBPOPULATION; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; TH1 CELL; TH2 CELL;

ANIMALIA; LEISHMANIA AMAZONENSIS; LEISHMANIA MAJOR; PROTOZOA;

EID: 0036325563     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.2002.66.338     Document Type: Article

References (43)

1. Chemotherapy for leishmaniasis: Biochemical mechanisms, clinical efficacy, and future strategies
2. 2 production and antileishmanial capacity of human cultured monocytes mediated by IFN-γ
3. Cytokine interactions in experimental cutaneous leishmaniasis. Interleukin 4 synergizes with interferon-γ to activate murine macrophages for killing of Leishmania major amastigotes
4. The regulation of immunity to Leishmania major
5. Experimental infection of BALB/c mice with Leishmania panamensis and Leishmania mexicana: Induction of early IFN-γ but not IL-4 is associated with the development of cutaneous lesions
6. Reciprocal expression of interferon γ or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets
7. Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon γ-independent mechanism
8. Immune responses associated with susceptibility of C57BL/10 mice to Leishmania amazonensis
9. In vivo protective effect of the lectin from Canavalia brasiliensis on BALB/c mice infected by Leishmania amazonensis
10. Transforming growth factor-β in leishmanial infection: A parasite escape mechanism
11. IL-4-independent inhibition of IL-12 responsiveness during Leishmania amazonemis infection
12. Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection
13. Leishmania amazonensis: Cultivation and characterization of axenic amastigote-like organisms
14. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
15. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
16. + T cells in vivo
17. Reconstitution of Leishmania immunity in severe combined immunodeficient mice using Th1- and Th2-like cell lines
18. TH1 and TH2 cell antigen receptors in experimental leishmaniasis
19. + T cells instructs Th2 development and susceptibility to Leishmania major in BALB/c mice
20. Leishmania pifanoi amastigote antigens protect mice against cutaneous leishmaniasis
21. + T cells in pathogenesis associated with Leishmania amazonensis infection
22. Interleukin-12 is required for interferon-γ production and lethality in lipopolysaccharide-induced shock in mice
23. + T cells to express interleukin 4 and upregulates expression of the chemokine receptor, Blr-1
24. + lymph node cells during experimental murine leishmaniasis in resistant and susceptible mice
25. M-1/M-2 macrophages and the Th1/Th2 paradigm
26. Antigen presentation by macrophages harboring intravesicular pathogens
27. The instructive role of dendritic cells on T cell responses: Lineages, plasticity and kinetics
28. Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo
29. Induction of a Th2 population from a polarized Leishmania-specific Th1 population by in vitro culture with IL-4
30. Production of the haemopoietic growth factors GM-CSF and interleukin-3 by mast cells in response to 1gE receptor-mediated activation
31. Tumor necrosis factor a and transforming growth factor β upregulate astrocyte expression of monocyte chemoattractant protein-1
32. Disruption of the murine interleukin-4 gene inhibits disease progression during Leishmania mexicana infection but does not increase control of Leishmania donovani infection
33. Local suppression of IFN-γ in hepatic granulomas correlates with tissue-specific replication of Leishmania chagasi
34. Influence of the host and parasite strain in a mouse model of visceral Leishmania infanium infection
35. A novel Leishmania infantum recombinant antigen which elicits interleukin 10 production by peripheral blood mononuclear cells of patients with visceral leishmaniasis
36. A recombinant Leishmania antigen that stimulates human peripheral blood mononuclear cells to express a Th1-type cytokine profile and to produce interleukin 12
37. Expression cloning of a protective Leishmania antigen
38. + T cells to rapidly secrete IL-4 in BALB/c mice infected with Leishmania major
39. + T cells in resistant mice upon infection with Leishmania major
40. Coordinate regulation of complex T cell populations responding to bacterial infection
41. IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis
42. T-cell responses to immunodominant LACK antigen do not play a critical role in determining susceptibility of BALB/c mice to Leishmania maxicana
43. Leishmania donovani p36 (LACK) DNA vaccine is highly immunogenic but not protective against experimental visceral leishmaniasis