Androgen-dependent expression of FcγRIIB2 by thyrocytes from patients with autoimmune Graves' disease: A possible molecular clue for sex dependence of autoimmune disease

FASEB Journal

Volumn 16, Issue 9, 2002, Pages 1087-1092

  Estienne, Valérie ^a   Duthoit, Christine ^a   Reichert, Manuela ^a   Praetor, Asja ^a   Carayon, Pierre ^a   Hunziker, Walter ^a   Ruf, Jean ^a  

^a INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

Author keywords

Autoimmune diseases; IgG Fc receptors; Sex dependence

Indexed keywords

ANDROSTANOLONE; FC RECEPTOR; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2;

ANTIBODY RESPONSE; ARTICLE; AUTOIMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; FEMININITY; GRAVES DISEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SEX DIFFERENCE; SEX RATIO; THYROID CELL;

ANTIGENS, CD; CELLS, CULTURED; DIHYDROTESTOSTERONE; ESTRADIOL; GENE EXPRESSION REGULATION; GRAVES DISEASE; HUMANS; IMMUNOGLOBULIN G; RECEPTORS, IGG; RNA, MESSENGER; SEX FACTORS; THYROID GLAND;

EID: 0036317991     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.01-0998hyp     Document Type: Article

References (39)

1. Sex differences in autoimmune disease
2. Autoimmune diseases: Genes, bugs and failed regulation
3. Autoimmune thyroid disease: Further developments in our understanding
4. Lectin-induced expression of DR antigen on human cultured follicular thyroid cells
5. Epithelial cells expressing aberrant MHC class II determinants can present antigen to cloned human T cells
6. Hyperexpression of transporter in antigen processing-1 (TAP-1) in thyroid glands affected by autoimmunity: A contributing factor to the breach of tolerance to thyroid antigens?
7. Proteasome subunits, low-molecular-mass polypeptides 2 and 7 are hyperexpressed by target cells in autoimmune thyroid disease but not in insulin-dependent diabetes mellitus: Implications for autoimmunity
8. HLA-DM and invariant chain are expressed by thyroid follicular cells, enabling the expression of compact DR molecules
9. Production of immunoreactive thyroglobulin C-terminal fragments during thyroid hormone synthesis
10. H202-induced production of a 40-kDa immunoreactive thyroglobulin fragment in human thyroid cells: The onset of thyroid autoimmunity?
11. Enhancing or suppressive effects of antibodies on processing of a pathogenic T cell epitope in thyroglobulin
12. Fc receptor biology
13. How can cryptic epitopes trigger auto-immunity?
14. Role of B-cell and Fc receptors in the selection of T-cell epitopes
15. Effects of androgen treatment on expression of macrophage Fcgamma receptors
16. Enhancement of splenic-macrophage Fcgamma receptor expression by treatment with estrogens
17. Human thyroid epithelial cells cultured in monolayers. I. Decreased thyroglobulin and cAMP response to TSH in 12-week-old secondary and tertiary cultures
18. Immunohistochemical study of thyroid peroxidase in normal, hyperplastic, and neoplastic human thyroid tissues
19. Human neutrophil Fc gamma receptor distribution and structure
20. Intracellular traffic of the MHC class I-like IgG Fc receptor, FcRn, expressed in epithelial MDCK cells
21. Cloning and characterization of the bovine MHC class I-like Fc receptor
22. Quantification of porcine cytokine gene expression using RT-PCR, a homologous internal control and chemiluminescence for microplate
23. Cyproterone acetate-mechanism of action and clinical effectiveness in prostate cancer treatment
24. Epithelial transcytosis of immunoglobulins
25. Fc receptors and their interactions with immunoglobulins
26. Expression of macrophage-lymphocyte Fc receptors in Madin-Darby canine kidney cells: Polarity and transcytosis differ for isoforms with or without coated pit localization domains
27. Multiple roles for the major histocompatibility complex class I-related receptor FcRn
28. Transcytosis of IgG from the basolateral to the apical membrane of human thyrocytes in autoimmune thyroid disease
29. Ultrastructural localization of IgG and TPO in autoimmune thyrocytes referring to the transcytosis of IgG and the antigen presentation of TPO
30. Identification and function of neonatal Fc receptor in mammary gland of lactating mice
31. Intracellular protein transport to the thyrocyte plasma membrane: Potential implications for thyroid physiology
32. Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytes
33. H (1992) Cytoplasmic domain heterogeneity and functions of IgG Fc receptors in B lymphocytes
34. Hyperinducibility of HLA class II expression of thyroid follicular cells from Graves' disease. A primary defect?
35. Testosterone therapy ameliorates experimental autoimmune encephalomyelitis and induces a T helper 2 bias in the autoantigen-specific T lymphocyte response
36. Beneficial effect of testesterone in the treatment of chronic autoimmune thyroiditis in rats
37. Studies of the regulatory effects of the sex hormones on antibody formation and stem cell differentiation
38. Sex-associated differences in the regulation of immune responses controlled by the MHC of the mouse
39. A differential nuclear uptake and retention of 3H-androgens in the thyroids of baboons