Genetic dissection of retinoic acid function in epidermis physiology;Dissection génétique de la fonction de l'acide rètinoïque dans la physiologie de l'èpiderme

Annales de Dermatologie et de Venereologie

Volumn 129, Issue 5 II, 2002, Pages 793-799

  Ghyselinck, N B ^a   Chapellier, B ^a   Calleja C ^a   Indra, A Kumar ^a   Li, M ^a   Messaddeq, N ^a   Mark, M ^a   Metzger, D ^a   Chambon, P ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; RECEPTOR SUBTYPE; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID RECEPTOR BETA; RETINOIC ACID RECEPTOR GAMMA; RETINOID X RECEPTOR; VITAMIN D RECEPTOR;

ALOPECIA; ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; DEGENERATION; DNA SEQUENCE; EPIDERMIS; GENETIC ANALYSIS; HAIR FOLLICLE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SOMATIC MUTATION;

ALOPECIA; ANIMALS; DNA; GENE EXPRESSION REGULATION; HAIR FOLLICLE; KERATOLYTIC AGENTS; MICE; POINT MUTATION; RECEPTORS, RETINOIC ACID; SIGNAL TRANSDUCTION; SKIN PHYSIOLOGY; TRETINOIN;

EID: 0036314904     PISSN: 01519638     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (61)

1. Tissue changes following deprivation of fat-soluble A vitamin
2. The proteins of the embryonic chick epidermis II. During culture in serum-containing medium with and without added vitamin A
3. Regulation of terminal differentiation of cultured human keratinocytes by vitamin A
4. Molecular mechanisms of retinoid actions in skin
5. Cutaneous lesions associated with a deficiency in vitamin A in man
6. A decade of molecular biology of retinoic acid receptors
7. The coregulator exchange in transcriptional functions of nuclear receptors
8. Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life
9. Retinoids and mammalian development
10. Skin abnormalities generated by temporally controlled RXRalpha mutations in mouse epidermis
11. Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development
12. A genetic dissection of the retinoid signalling pathway in the mouse
13. Function of retinoic acid receptor gamma in the mouse
14. Limited specificity and large overlap of the functions of the mouse RAR gamma 1 and RAR gamma 2 isoforms
15. The epidermal permeability barrier
16. Structural relationship between epidermal lipid lamellae, lamellar bodies and desmosomes in human epidermis: An ultrastructural study
17. Desmosomes, corneosomes and desquamation. An ultrastructural study of adult pig epidermis
18. Evidence for a role of corneodesmosin, a protein which may serve to modify desmosomes during cornification, in stratum corneum cell cohesion and desquamation
19. Corneodesmosin, a corneo-desmosome-specific basic protein, is expressed in the cornified epithelia of the pig, guinea pig, rat and mouse
20. Characterization and purification of human corneodesmosin, an epidermal basic glycoprotein associated with corneocyte-specific modified desmosomes
21. RXRalpha ablation in skin keratinocytes results in alopecia and epidermal alterations
22. The RXRalpha ligand-dependent activation function 2 (AF-2) is important for mouse development
23. High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice
24. Role of the retinoic acid receptor beta (RARbeta) during mouse development
25. Roles of retinoic acid receptors in early embryonic morphogenesis and hindbrain patterning
26. Site- and time-specific gene targeting in the mouse
27. Bacteriophage P1 site-specific recombination. I. Recombination between IoxP sites
28. Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1
29. Ligandactivated site-specific recombination in mice
30. Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains
31. Spatio-temporally controlled site-specific somatic mutagenesis in the mouse
32. T2 recombinases
33. Generalized lacz expression with the ROSA26 Cre reporter strain
34. Mouse models for the study of human hair loss
35. Molecular and functional aspects of the hairless (hr) gene in laboratory rodents and humans
36. The Vitamin D receptor and the syndrome of hereditary 1,25-dihydroxyvitamin D-resistant rickets
37. Targeted ablation of the vitamin D receptor: An animal model of vitamin D-dependent rickets type II with alopecia
38. Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning
39. Evaluation of keratinocyte proliferation and differentiation in vitamin D receptor knockout mice
40. Vitamin D receptors repress basal transcription and exert dominant negative activity on triiodothyronine-mediated transcriptional activity
41. Characterization of retinoic acid receptor-deficient keratinocytes
42. A conditional floxed (IoxP-flanked) allele for the Retinoic Acid Receptor alpha (RARalpha) gene
43. A conditional floxed (IoxP-flanked) allele for the Retinoic Acid Receptor gamma (RARgamma) gene
44. Vitamin A deficiency in the germ free rat
45. Thyroid hormone receptor betal is expressed in the human hair follicle
46. Keratinocyte differentiation is stimulated by activators of the nuclear hormone receptor PPARalpha
47. Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta (delta)
48. Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice
49. Retinoic acid receptor gamma mediates topical retinoid efficacy and irritation in animal models
50. A comparative study of the induction of epidermal hyperplasia by natural and synthetic retinoids
51. Receptor specificity of retinoid-induced epidermal hyperplasia: Effect of RXR-selective agonists and correlation with topical irritation
52. Paracrine regulation of keratinocyte proliferation and differentiation
53. Identification of heparin-binding EGF-like growth factor as a target in intercellular regulation of epidermal basal cell growth by suprabasal retinoic acid receptors
54. The EGF-receptor - An essential regulator of multiple epidermal functions
55. Retinoid regulation of heparin-binding EGF-like growth factor gene expression in human keratinocytes and skin
56. Immunohistochemical localization of heparin-binding epidermal growth factor-like growth factor in normal skin and skin cancers
57. Vitamin A and wound healing
58. Appearance of heparin-binding EGF-like growth factor in wound fluid as a response to injury
59. Production of heparin-binding epidermal growth factor-like growth factor (HB-EGF) at sites of thermal injury in pediatric patients
60. Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled