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Volumn 69, Issue 5, 1997, Pages 2075-2086

Cooperative interception of neuronal apoptosis by BCL-2 and BAG-1 expression: Prevention of caspase activation and reduced production of reactive oxygen species

Author keywords

BAG 1; BCL 2; Caspases; Cell death pathway; CPP32; Free radicals; Neural apoptosis

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; BAG 1 PROTEIN; BINDING PROTEIN; CASPASE; N TERT BUTYL ALPHA PHENYLNITRONE; PROTEIN BCL 2; PROTEINASE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

EID: 0030828019     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.69052075.x     Document Type: Article
Times cited : (108)

References (70)
  • 1
    • 0027243086 scopus 로고
    • The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis
    • Allsopp T. E., Wyatt S., Paterson H. F., and Davies A. M. (1993) The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis. Cell 73, 295-307.
    • (1993) Cell , vol.73 , pp. 295-307
    • Allsopp, T.E.1    Wyatt, S.2    Paterson, H.F.3    Davies, A.M.4
  • 5
    • 0030017892 scopus 로고    scopus 로고
    • The low affinity nerve growth factor receptor p75 (NGFR) mediates death of PC12 cells after nerve growth factor withdrawal
    • Barren G. L. and Georgiou A. (1996) The low affinity nerve growth factor receptor p75 (NGFR) mediates death of PC12 cells after nerve growth factor withdrawal. J. Neurosci. Res. 45, 117-128.
    • (1996) J. Neurosci. Res. , vol.45 , pp. 117-128
    • Barren, G.L.1    Georgiou, A.2
  • 6
    • 0026046948 scopus 로고
    • Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: Correlation with suppression of endonuclease activity
    • Batistatou A. and Greene L. A. (1991) Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activity. J. Cell Biol. 115, 461-471.
    • (1991) J. Cell Biol. , vol.115 , pp. 461-471
    • Batistatou, A.1    Greene, L.A.2
  • 7
    • 0027427493 scopus 로고
    • Bcl-2 affects survival but not neuronal differentiation of PC12 cells
    • Batistatou A., Merry D. E., Korsmeyer S. J., and Greene L, A. (1993) Bcl-2 affects survival but not neuronal differentiation of PC12 cells. J. Neurosci. 13, 4422-4428.
    • (1993) J. Neurosci. , vol.13 , pp. 4422-4428
    • Batistatou, A.1    Merry, D.E.2    Korsmeyer, S.J.3    Greene, L.A.4
  • 8
    • 0030011398 scopus 로고    scopus 로고
    • Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1 and TNF receptor-induced cell death
    • Boldin M. P., Goncharow T. M., Goltsev Y. V., and Wallach D. (1996) Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1 and TNF receptor-induced cell death. Cell 85, 803-815.
    • (1996) Cell , vol.85 , pp. 803-815
    • Boldin, M.P.1    Goncharow, T.M.2    Goltsev, Y.V.3    Wallach, D.4
  • 9
    • 0029614765 scopus 로고
    • Neural apoptosis
    • Bredesen D. E. (1995) Neural apoptosis. Ann. Neurol. 38, 839-851.
    • (1995) Ann. Neurol. , vol.38 , pp. 839-851
    • Bredesen, D.E.1
  • 10
    • 0029805770 scopus 로고    scopus 로고
    • Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75
    • Casaccia-Bonnefil P., Carter B. D., Dobrowsky R. T., and Chao M. V. (1996) Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75. Nature 383, 716-719.
    • (1996) Nature , vol.383 , pp. 716-719
    • Casaccia-Bonnefil, P.1    Carter, B.D.2    Dobrowsky, R.T.3    Chao, M.V.4
  • 11
    • 0001343810 scopus 로고    scopus 로고
    • Bcl-2 promotes regeneration of severed axons in mammalian CNS
    • Chen D. F., Schneider G. E., Martinou J.-C., and Tonegawa S. (1997) Bcl-2 promotes regeneration of severed axons in mammalian CNS. Nature 385, 434-439.
    • (1997) Nature , vol.385 , pp. 434-439
    • Chen, D.F.1    Schneider, G.E.2    Martinou, J.-C.3    Tonegawa, S.4
  • 14
    • 0029814736 scopus 로고    scopus 로고
    • Bcl-2 sensitivity differentiates two pathways for motoneuronal death in the wobbler mutant mice
    • Coulpier M., Junier M.-P., Peschanski M., and Dreyfus P. A. (1996) Bcl-2 sensitivity differentiates two pathways for motoneuronal death in the wobbler mutant mice. J. Neurosci. 16, 5897-5904.
    • (1996) J. Neurosci. , vol.16 , pp. 5897-5904
    • Coulpier, M.1    Junier, M.-P.2    Peschanski, M.3    Dreyfus, P.A.4
  • 16
    • 0027537118 scopus 로고
    • Suppression of apoptosis in a cytotoxic T-cell line by interleukin2-mediated gene transcription and deregulated expression of the protooncogene bcl-2
    • Deng G. and Podack E. R. (1993) Suppression of apoptosis in a cytotoxic T-cell line by interleukin2-mediated gene transcription and deregulated expression of the protooncogene bcl-2. Proc. Natl. Acad. Sci. USA 90, 2189-2193.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2189-2193
    • Deng, G.1    Podack, E.R.2
  • 17
    • 0029022365 scopus 로고
    • Involvement of an ICE-like protease in Fas-mediated apoptosis
    • Enari M., Hug H., and Nagata S. (1995) Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature 375, 78-81.
    • (1995) Nature , vol.375 , pp. 78-81
    • Enari, M.1    Hug, H.2    Nagata, S.3
  • 18
    • 0027946686 scopus 로고
    • Altered gene expression in neurons during programmed cell death: Identification of c-jun as necessary for neuronal apoptosis
    • Estus S., Zaks W. J., Freeman R. S., Gruda M., Bravo R., and Johnson E. M. Jr. (1994) Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis. J. Cell Biol. 127, 1717-1727.
    • (1994) J. Cell Biol. , vol.127 , pp. 1717-1727
    • Estus, S.1    Zaks, W.J.2    Freeman, R.S.3    Gruda, M.4    Bravo, R.5    Johnson Jr., E.M.6
  • 19
    • 0029895743 scopus 로고    scopus 로고
    • Neurotrophic factors and their receptors: Implications of genetic studies
    • Farinas I. and Reichardt L. F. (1996) Neurotrophic factors and their receptors: implications of genetic studies. Semin. Neurosci. 8, 133-143.
    • (1996) Semin. Neurosci. , vol.8 , pp. 133-143
    • Farinas, I.1    Reichardt, L.F.2
  • 20
    • 0029972440 scopus 로고    scopus 로고
    • Cell cycle blockers mimosine, ciclopirox, and deferoxamine prevent the death of PC12 cells and postmitotic sympathetic neurons after removal of trophic support
    • Farinelli S. E. and Greene L. A. (1996) Cell cycle blockers mimosine, ciclopirox, and deferoxamine prevent the death of PC12 cells and postmitotic sympathetic neurons after removal of trophic support. J. Neurosci. 16, 1150-1162.
    • (1996) J. Neurosci. , vol.16 , pp. 1150-1162
    • Farinelli, S.E.1    Greene, L.A.2
  • 21
    • 0027973061 scopus 로고
    • CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1β-converting enzyme
    • Fernandas-Alnemri T., Litwack G., and Alnemri E. S. (1994) CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1β-converting enzyme. J. Biol. Chem. 269, 30761-30764.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30761-30764
    • Fernandas-Alnemri, T.1    Litwack, G.2    Alnemri, E.S.3
  • 22
    • 0028916027 scopus 로고
    • N-Acetylcysteine (D- and L-stereoisomers) prevents apoptotic death of neuronal cells
    • Ferrari G., Yan C. Y. I., and Greene L. A. (1995) N-Acetylcysteine (D- and L-stereoisomers) prevents apoptotic death of neuronal cells. J. Neurosci. 15, 2857-2866.
    • (1995) J. Neurosci. , vol.15 , pp. 2857-2866
    • Ferrari, G.1    Yan, C.Y.I.2    Greene, L.A.3
  • 23
    • 0029995766 scopus 로고    scopus 로고
    • A licence to kill
    • Fraser A. and Evan G. (1996) A licence to kill. Cell 85, 781-784.
    • (1996) Cell , vol.85 , pp. 781-784
    • Fraser, A.1    Evan, G.2
  • 25
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y., Sherman Y., and Ben-Sasson S. A. (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119, 493-501.
    • (1992) J. Cell Biol. , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 26
    • 0345704610 scopus 로고
    • Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
    • Greene L. and Tischler A. (1976) Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. USA 73, 2424-2428.
    • (1976) Proc. Natl. Acad. Sci. USA , vol.73 , pp. 2424-2428
    • Greene, L.1    Tischler, A.2
  • 27
    • 0028893492 scopus 로고
    • Superoxide dismutase delays neuronal apoptosis: A role for reactive oxygen species in programmed neuronal death
    • Greenlund L. J. S., Deckwerth T. L., and Johnson E. M. (1995) Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death. Neuron 14, 303-315.
    • (1995) Neuron , vol.14 , pp. 303-315
    • Greenlund, L.J.S.1    Deckwerth, T.L.2    Johnson, E.M.3
  • 28
    • 0028288277 scopus 로고
    • C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian protooncogene bcl-2
    • Hengartner M. and Horvitz H. (1994) C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian protooncogene bcl-2. Cell 76, 665-676.
    • (1994) Cell , vol.76 , pp. 665-676
    • Hengartner, M.1    Horvitz, H.2
  • 30
    • 0028939139 scopus 로고
    • Programmed cell death and Bcl-2 protection in very low oxygen
    • Jacobson M. and Raff M. (1995) Programmed cell death and Bcl-2 protection in very low oxygen. Nature 374, 811-813.
    • (1995) Nature , vol.374 , pp. 811-813
    • Jacobson, M.1    Raff, M.2
  • 31
    • 0027396983 scopus 로고
    • Molecular mechanisms of developmental neuronal death
    • Johnson E. M. and Deckwerth T. L. (1993) Molecular mechanisms of developmental neuronal death. Annu. Rev. Neurosci. 16, 31 -46.
    • (1993) Annu. Rev. Neurosci. , vol.16 , pp. 31-46
    • Johnson, E.M.1    Deckwerth, T.L.2
  • 33
    • 0027156025 scopus 로고
    • In vivo spin trapping of xenobiotic free radical metabolites
    • Knecht K. T. and Mason R. P. (1993) In vivo spin trapping of xenobiotic free radical metabolites. Arch. Biochem. Biophys. 303, 185-194.
    • (1993) Arch. Biochem. Biophys. , vol.303 , pp. 185-194
    • Knecht, K.T.1    Mason, R.P.2
  • 34
    • 0028920863 scopus 로고
    • Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta-converting enzyme
    • Kuida K., Lippke J. A., Ku G., Harding M. W., Livingston D. J., Su M. S., and Flavell R. A. (1995) Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta-converting enzyme. Science 267, 2000-2003.
    • (1995) Science , vol.267 , pp. 2000-2003
    • Kuida, K.1    Lippke, J.A.2    Ku, G.3    Harding, M.W.4    Livingston, D.J.5    Su, M.S.6    Flavell, R.A.7
  • 38
    • 0030897988 scopus 로고    scopus 로고
    • Substrate and inhibitor specificity of interleukin-1β-converting enzyme and related caspases
    • Margolin N., Raybuck S. A., Wilson K. P., Chen W., Fox T., Gu Y., and Livingston D. J. (1997) Substrate and inhibitor specificity of interleukin-1β-converting enzyme and related caspases. J. Biol. Chem. 272, 7223-7228.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7223-7228
    • Margolin, N.1    Raybuck, S.A.2    Wilson, K.P.3    Chen, W.4    Fox, T.5    Gu, Y.6    Livingston, D.J.7
  • 39
    • 0026443573 scopus 로고
    • Biochemical characterization of programmed cell death in NGF-deprived sympathetic neurons
    • Martin D. P., Ito A., Horigome K., Lampe P. A., and Johnson E. M. Jr. (1992) Biochemical characterization of programmed cell death in NGF-deprived sympathetic neurons. J. Neurobiol. 23, 1205-1220.
    • (1992) J. Neurobiol. , vol.23 , pp. 1205-1220
    • Martin, D.P.1    Ito, A.2    Horigome, K.3    Lampe, P.A.4    Johnson Jr., E.M.5
  • 40
    • 0029125701 scopus 로고
    • Protease activation during apoptosis: Death by a thousand cuts?
    • Martin S. J. and Green D. R. (1995) Protease activation during apoptosis: death by a thousand cuts? Cell 82, 1-20.
    • (1995) Cell , vol.82 , pp. 1-20
    • Martin, S.J.1    Green, D.R.2
  • 41
    • 0027071804 scopus 로고
    • Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons
    • Mesner P. W., Winters T. R., and Green S. H. (1992) Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons. J. Cell Biol. 119, 1669-1680.
    • (1992) J. Cell Biol. , vol.119 , pp. 1669-1680
    • Mesner, P.W.1    Winters, T.R.2    Green, S.H.3
  • 42
    • 0028839253 scopus 로고
    • A timetable of events during programmed cell death induced by trophic factor withdrawal from neuronal PC12 cells
    • Mesner P. W., Epting C. L., Hegarty J. L., and Green S. H. (1995) A timetable of events during programmed cell death induced by trophic factor withdrawal from neuronal PC12 cells. J. Neurosci. 15, 7357-7366.
    • (1995) J. Neurosci. , vol.15 , pp. 7357-7366
    • Mesner, P.W.1    Epting, C.L.2    Hegarty, J.L.3    Green, S.H.4
  • 44
    • 0027449187 scopus 로고
    • Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3
    • Miura M., Zhu H., Rotello R., Hatwieg E. A., and Yuan J. (1993) Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell 75, 653-660.
    • (1993) Cell , vol.75 , pp. 653-660
    • Miura, M.1    Zhu, H.2    Rotello, R.3    Hatwieg, E.A.4    Yuan, J.5
  • 45
    • 0029114963 scopus 로고
    • Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway
    • Miura M., Friedlander R. M., and Yuan J. (1995) Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway. Proc. Natl. Acad. Sci. USA 92, 8318-8322.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8318-8322
    • Miura, M.1    Friedlander, R.M.2    Yuan, J.3
  • 47
    • 0026058318 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim R. W. (1991) Cell death during development of the nervous system. Annu. Rev. Neurosci. 14, 453-501.
    • (1991) Annu. Rev. Neurosci. , vol.14 , pp. 453-501
    • Oppenheim, R.W.1
  • 48
    • 0027320760 scopus 로고
    • A system for characterizing cellular and molecular events in programmed neuronal cell death
    • Pittman R. N., Wang S., DiBenedetto A. J., and Mills J. C. (1993) A system for characterizing cellular and molecular events in programmed neuronal cell death. J. Neurosci. 13, 3669-3680.
    • (1993) J. Neurosci. , vol.13 , pp. 3669-3680
    • Pittman, R.N.1    Wang, S.2    DiBenedetto, A.J.3    Mills, J.C.4
  • 50
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed J. C. (1994) Bcl-2 and the regulation of programmed cell death. J. Cell Biol. 124, 1-6.
    • (1994) J. Cell Biol. , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 51
    • 0025939423 scopus 로고
    • Multiple agents rescue PC12 cells from serum free cell death by translation- and transcription-independent mechanisms
    • Rukenstein A., Rydel R. E., and Greene L. A. (1991) Multiple agents rescue PC12 cells from serum free cell death by translation- and transcription-independent mechanisms. J. Neurosci. 11, 2552-2563.
    • (1991) J. Neurosci. , vol.11 , pp. 2552-2563
    • Rukenstein, A.1    Rydel, R.E.2    Greene, L.A.3
  • 53
    • 0029954311 scopus 로고    scopus 로고
    • Potassium deprivation-induced apoptosis of cerebellar granule neurons: A sequential requirement for new mRNa and protein synthesis, ICE-like protease activity, and reactive oxygen species
    • Schulz J. B., Weller M., and Klockgether T. (1996) Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species. J. Neurosci. 16, 4696-4706.
    • (1996) J. Neurosci. , vol.16 , pp. 4696-4706
    • Schulz, J.B.1    Weller, M.2    Klockgether, T.3
  • 55
    • 0029816144 scopus 로고    scopus 로고
    • Bcl-2 expression in neural cells blocks activation of ICE/CED-3 family proteases during apoptosis
    • Srinivasan A., Foster L. M., Testa M.-P., Örd T., Keane R. W., Bredesen D. E., and Kayalar C. (1996) Bcl-2 expression in neural cells blocks activation of ICE/CED-3 family proteases during apoptosis. J. Neurosci. 16, 5654-5660.
    • (1996) J. Neurosci. , vol.16 , pp. 5654-5660
    • Srinivasan, A.1    Foster, L.M.2    Testa, M.-P.3    Örd, T.4    Keane, R.W.5    Bredesen, D.E.6    Kayalar, C.7
  • 57
    • 0028847915 scopus 로고
    • Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity
    • Takayama S., Sato T., Krajewski S., Kochel K., Irie S., Millan J. A., and Reed J. C. (1995) Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity. Cell 80, 279-284.
    • (1995) Cell , vol.80 , pp. 279-284
    • Takayama, S.1    Sato, T.2    Krajewski, S.3    Kochel, K.4    Irie, S.5    Millan, J.A.6    Reed, J.C.7
  • 58
    • 0028990125 scopus 로고
    • Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly (ADP-ribose) polymerase
    • Tewari M., Quan L. T., O'Rourke K., Desnoyers S., Zeng Z., Beidler D. R., Poirier G. G., Salvesen G. S., and Dixit S. M. (1995) Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly (ADP-ribose) polymerase. Cell 81, 801-809.
    • (1995) Cell , vol.81 , pp. 801-809
    • Tewari, M.1    Quan, L.T.2    O'Rourke, K.3    Desnoyers, S.4    Zeng, Z.5    Beidler, D.R.6    Poirier, G.G.7    Salvesen, G.S.8    Dixit, S.M.9
  • 59
    • 0029890689 scopus 로고    scopus 로고
    • The contrasting roles of ICE family proteases and interleukin-1β in apoptosis induced by trophic factor withdrawal and by copper/zinc Superoxide dismutase down-regulation
    • Troy C. M., Stefanis L., Prochiantz A., Greene L. A., and Shelanski M. L. (1996) The contrasting roles of ICE family proteases and interleukin-1β in apoptosis induced by trophic factor withdrawal and by copper/zinc Superoxide dismutase down-regulation. Proc. Natl. Acad. Sci. USA 93, 5635-5640.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5635-5640
    • Troy, C.M.1    Stefanis, L.2    Prochiantz, A.3    Greene, L.A.4    Shelanski, M.L.5
  • 60
    • 0031018396 scopus 로고    scopus 로고
    • Nedd2 is required for apoptosis after trophic factor withdrawal, but not Superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells
    • Troy C. M., Stefanis L., Greene L. A., and Shelanski M. L. (1997) Nedd2 is required for apoptosis after trophic factor withdrawal, but not Superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells. J. Neurosci. 17, 1911-1918.
    • (1997) J. Neurosci. , vol.17 , pp. 1911-1918
    • Troy, C.M.1    Stefanis, L.2    Greene, L.A.3    Shelanski, M.L.4
  • 61
    • 0027050145 scopus 로고
    • Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2
    • Vaux D. L., Weissman I. L., and Kim S. K. (1992) Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2. Science 258, 1955-1957.
    • (1992) Science , vol.258 , pp. 1955-1957
    • Vaux, D.L.1    Weissman, I.L.2    Kim, S.K.3
  • 62
    • 0028178471 scopus 로고
    • Transforming growth factor-β2 induces apoptosis of murine T cell clones without down-regulating bcl-2 mRNA expression
    • Weller M., Constam D. B., Malipiero U., and Fontana A. (1994a) Transforming growth factor-β2 induces apoptosis of murine T cell clones without down-regulating bcl-2 mRNA expression. Eur. J. Immunol. 24, 1293-1300.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1293-1300
    • Weller, M.1    Constam, D.B.2    Malipiero, U.3    Fontana, A.4
  • 63
    • 0027990763 scopus 로고
    • Anti-Fas/APO-1 antibody-mediated apoptosis of cultured human glioma cells: Induction and modulation of sensitivity by cytokines
    • Weller M., Frei K., Groscurth P., Krammer P. H., Yonekawa Y., and Fontana A. (1994b) Anti-Fas/APO-1 antibody-mediated apoptosis of cultured human glioma cells: induction and modulation of sensitivity by cytokines. J. Clin. Invest. 94, 954-964.
    • (1994) J. Clin. Invest. , vol.94 , pp. 954-964
    • Weller, M.1    Frei, K.2    Groscurth, P.3    Krammer, P.H.4    Yonekawa, Y.5    Fontana, A.6
  • 64
    • 0029010631 scopus 로고
    • Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation
    • Weller M., Malipiero U., Aguzzi A., Reed J. C., and Fontana A. (1995) Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation. J. Clin. Invest. 95, 2633-2643.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2633-2643
    • Weller, M.1    Malipiero, U.2    Aguzzi, A.3    Reed, J.C.4    Fontana, A.5
  • 67
    • 0027495786 scopus 로고
    • In situ labeling of granule cells for apoptosis-associated DNA fragmentation reveals different mechanisms of cell loss in developing cerebellum
    • Wood K. A., Dipasquale B., and Youle R. J. (1993) In situ labeling of granule cells for apoptosis-associated DNA fragmentation reveals different mechanisms of cell loss in developing cerebellum. Neuron 11, 621-632.
    • (1993) Neuron , vol.11 , pp. 621-632
    • Wood, K.A.1    Dipasquale, B.2    Youle, R.J.3
  • 68
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
    • Yuan J., Shaham S., Ledoux S., Ellis H. M., and Horvitz H. R. (1993) The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell 75, 641-652.
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.1    Shaham, S.2    Ledoux, S.3    Ellis, H.M.4    Horvitz, H.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.