Mutation of the catalytic domain of the foamy virus reverse transcriptase leads to loss of processivity and infectivity

Journal of Virology

Volumn 76, Issue 15, 2002, Pages 7560-7570

  Rinke, Carolyn S ^a   Boyer, Paul L ^a   Sullivan, Mark D ^a   Hughes, Stephen H ^a   Linial, Maxine L ^a  

^a USA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3' AZIDO 2',3' DIDEOXY 5 METHYLCYTIDINE; 3' AZIDO 2',3' DIDEOXYURIDINE; EMTRICITABINE; FOSCARNET; LAMIVUDINE; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; VIRUS DNA; VIRUS ENZYME; ZALCITABINE; ZIDOVUDINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SENSITIVITY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; GENE MUTATION; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; REVERSE TRANSCRIPTION; REVERTANT; SPUMA VIRUS; VIRUS INFECTIVITY; VIRUS MUTANT; VIRUS REPLICATION;

ANIMALS; CATALYTIC DOMAIN; CELL LINE; CRICETINAE; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; MUTATION; PAN TROGLODYTES; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE INHIBITORS; RNA-DIRECTED DNA POLYMERASE; SPUMAVIRUS; TRANSCRIPTION, GENETIC; VIRION; VIRUS REPLICATION;

EID: 0036310388     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.76.15.7560-7570.2002     Document Type: Article

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