Inhibitors of G-proteins and protein kinases reduce the sensitization to mechanical stimulation and the desensitization to heat of spinothalamic tract neurons induced by intradermal injection of capsaicin in the primate

Experimental Brain Research

Volumn 115, Issue 1, 1997, Pages 15-24

  Sluka, K A ^a,b   Rees, H ^a   Chen, P S ^a   Tsuruoka, M ^a,c   Willis, W D ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c SHOWA UNIVERSITY   (Japan)

Author keywords

Dorsal horn; Protein kinase A; Protein kinase C; Second messengers; Spinal cord

Indexed keywords

CAPSAICIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN INHIBITOR; PROTEIN KINASE; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR;

ANIMAL EXPERIMENT; ARTICLE; DESENSITIZATION; HEAT; INTRADERMAL DRUG ADMINISTRATION; MECHANICAL STIMULATION; MICRODIALYSIS; MONKEY; NONHUMAN; PRESSURE; PRIORITY JOURNAL; SECOND MESSENGER; SPINAL CORD; SPINOTHALAMIC TRACT; TIME;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ADENOSINE DIPHOSPHATE; ANIMALS; CAPSAICIN; ENZYME INHIBITORS; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HAPLORHINI; HEAT; INJECTIONS, INTRADERMAL; ISOQUINOLINES; MICRODIALYSIS; NERVE FIBERS; NEURAL PATHWAYS; PHYSICAL STIMULATION; PIPERIDINES; PROTEIN KINASE INHIBITORS; SPINAL CORD; SULFONAMIDES; THALAMUS; THIONUCLEOTIDES;

EID: 0030924661     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00005675     Document Type: Article

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