Site-specific recombination in eukaryotic cells mediated by mutant λ integrases: Implications for synaptic complex formation and the reactivity of episomal DNA segments

Journal of Molecular Biology

Volumn 319, Issue 2, 2002, Pages 305-314

  Christ, Nicole ^a   Corona, Teresa ^a   Dröge, Peter ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Episomal DNA reactivity; Human cells; Nucleoprotein complex; Site specific recombination; integrase

Indexed keywords

CRE RECOMBINASE; DNA BINDING PROTEIN; INTEGRATION HOST FACTOR; LAMBDA INTEGRASE; MUTANT PROTEIN; PROTEIN FLP; PROTEIN FRT; PROTEIN IOXP; RECOMBINASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; BIOTECHNOLOGICAL PROCEDURES; CONTROLLED STUDY; DNA BINDING; DNA RECOMBINATION; DNA SEQUENCE; EPISOME; EUKARYOTIC CELL; EXPRESSION VECTOR; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; STIMULATION; SYNAPTOGENESIS;

EUKARYOTA; VECTORS;

EID: 0036300997     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00327-3     Document Type: Article

References (22)

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3. The small DNA binding domain of lambda integrase is a context-sensitive modulator of recombinase function
4. The amino terminus of bacteriophage lambda integrase is involved in protein-protein interactions during recombination
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6. Alterations in the directionality of λ site-specific recombination catalyzed by mutant integrases in vivo
7. Purification and properties of Int-h, a variant protein involved in site-specific recombination of bacteriophage λ
8. Characterization of the interaction between the Lambda intasome and att B
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13. Intra- and intermolecular site-specific recombination in plant cells mediated by bacteriophage P1 recombinase
14. Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells
15. High mobility of proteins in the mammalian cell nucleus
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19. Architectural elements in nucleoprotein complexes: Interchangeability of specific and non-specific DNA binding proteins
20. High local protein concentrations at promoters: Strategies in prokaryotic and eukaryotic cells
21. Branch migration and Holliday junction resolution catalyzed by activities in mammalian cells
22. Genomic manipulations of mouse embryonic stem cells by mutant λ integrase