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Volumn 288, Issue 5, 1999, Pages 825-836

Alterations in the directionality of λ site-specific recombination catalyzed by mutant integrases in vivo

Author keywords

Holliday junction isomerization; Integration host factor; Site specific recombination; Strand exchange; integrase

Indexed keywords

DNA; INTEGRASE; INTEGRATION HOST FACTOR; MUTANT PROTEIN;

EID: 0345518010     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.2730     Document Type: Article
Times cited : (12)

References (48)
  • 1
    • 0030950350 scopus 로고    scopus 로고
    • The isomeric preference of Holliday junctions influences resolution bias by λ integrase
    • Azaro A. M., Landy A. The isomeric preference of Holliday junctions influences resolution bias by λ integrase. EMBO J. 16:1997;3744-3755.
    • (1997) EMBO J. , vol.16 , pp. 3744-3755
    • Azaro, A.M.1    Landy, A.2
  • 2
    • 0020397021 scopus 로고
    • Site-specific DNA condensation and pairing mediated by the Int protein of bacteriophage λ
    • Better M., Lu C., Williams R. C., Echols H. Site-specific DNA condensation and pairing mediated by the Int protein of bacteriophage λ Proc. Natl Acad. Sci. USA. 79:1982;5837-5841.
    • (1982) Proc. Natl Acad. Sci. USA , vol.79 , pp. 5837-5841
    • Better, M.1    Lu, C.2    Williams, R.C.3    Echols, H.4
  • 3
    • 0026657060 scopus 로고
    • Symmetry in the mechanism of bacteriophage λ integrative recombination
    • Burgin A. B., Nash H. A. Symmetry in the mechanism of bacteriophage λ integrative recombination. Proc. Natl Acad. Sci. USA. 89:1992;9642-9646.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 9642-9646
    • Burgin, A.B.1    Nash, H.A.2
  • 4
    • 0029147088 scopus 로고
    • Identifying determinants of recombination specificity: Construction and characterization of mutant bacteriophage integrases
    • Dorgai L., Yagil E., Weisberg R. A. Identifying determinants of recombination specificity: construction and characterization of mutant bacteriophage integrases. J. Mol. Biol. 252:1995;178-188.
    • (1995) J. Mol. Biol. , vol.252 , pp. 178-188
    • Dorgai, L.1    Yagil, E.2    Weisberg, R.A.3
  • 5
    • 0343990557 scopus 로고
    • Recombination of knotted substrates by Tn 3 resolvase
    • Dröge P., Cozzarelli N. R. Recombination of knotted substrates by Tn 3 resolvase. Proc. Natl Acad. Sci. USA. 86:1989;6062-6066.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 6062-6066
    • Dröge, P.1    Cozzarelli, N.R.2
  • 6
    • 0025155363 scopus 로고
    • Interactions between λ Int molecules bound to sites in the region of strand exchange are required for efficient Holliday junction resolution
    • Franz B., Landy A. Interactions between λ Int molecules bound to sites in the region of strand exchange are required for efficient Holliday junction resolution. J. Mol. Biol. 215:1990;523-535.
    • (1990) J. Mol. Biol. , vol.215 , pp. 523-535
    • Franz, B.1    Landy, A.2
  • 7
    • 0028893895 scopus 로고
    • The Holliday junction intermediates of λ integrative and excisive recombination respond differently to the bending proteins, IHF and Xis
    • Franz B., Landy A. The Holliday junction intermediates of λ integrative and excisive recombination respond differently to the bending proteins, IHF and Xis. EMBO J. 14:1995;397-406.
    • (1995) EMBO J. , vol.14 , pp. 397-406
    • Franz, B.1    Landy, A.2
  • 8
    • 0027049067 scopus 로고
    • Deformation of DNA during site-specific recombination of bacteriophage λ: Replacement of IHF protein by HU protein or sequence-directed bends
    • Goodman S. D., Nicholson S. C., Nash H. A. Deformation of DNA during site-specific recombination of bacteriophage λ: replacement of IHF protein by HU protein or sequence-directed bends. Proc. Natl Acad. Sci. USA. 89:1992;11910-11914.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 11910-11914
    • Goodman, S.D.1    Nicholson, S.C.2    Nash, H.A.3
  • 9
    • 0032528271 scopus 로고    scopus 로고
    • Structure of the Holliday junction intermediate in Cre- loxP site-specific recombination
    • Gopaul D. N., Feng G., Van Duyne G. D. Structure of the Holliday junction intermediate in Cre- loxP site-specific recombination. EMBO J. 17:1998;4175-4187.
    • (1998) EMBO J. , vol.17 , pp. 4175-4187
    • Gopaul, D.N.1    Feng, G.2    Van Duyne, G.D.3
  • 10
    • 0030886293 scopus 로고    scopus 로고
    • Structure of Cre recombinase complexed with DNA in a site-specific recombination synapse
    • Guo K., Gopaul D. N., Van Duyne G. D. Structure of Cre recombinase complexed with DNA in a site-specific recombination synapse. Nature. 389:1997;40-47.
    • (1997) Nature , vol.389 , pp. 40-47
    • Guo, K.1    Gopaul, D.N.2    Van Duyne, G.D.3
  • 11
    • 0030721538 scopus 로고    scopus 로고
    • Transposition and site-specific recombination: Adapting DNA cut-and-paste mechanisms to a variety of genetic rearrangements
    • Hallet B., Sherratt D. J. Transposition and site-specific recombination: adapting DNA cut-and-paste mechanisms to a variety of genetic rearrangements. FEMS Microbiol. Rev. 21:1997;157-178.
    • (1997) FEMS Microbiol. Rev. , vol.21 , pp. 157-178
    • Hallet, B.1    Sherratt, D.J.2
  • 12
    • 0028125987 scopus 로고
    • Mapping the functional domains of bacteriophage lambda integrase protein
    • Han Y. W., Gumport R. I., Gardner J. F. Mapping the functional domains of bacteriophage lambda integrase protein. J. Mol. Biol. 235:1994;908-925.
    • (1994) J. Mol. Biol. , vol.235 , pp. 908-925
    • Han, Y.W.1    Gumport, R.I.2    Gardner, J.F.3
  • 13
    • 0020959710 scopus 로고
    • Studies on transformation of Escherichia coli with plasmids
    • Hanahan D. Studies on transformation of Escherichia coli with plasmids. J. Mol. Biol. 166:1983;557-580.
    • (1983) J. Mol. Biol. , vol.166 , pp. 557-580
    • Hanahan, D.1
  • 14
    • 0018415073 scopus 로고
    • Regulation of integration by coliphage λ: Activation of int transcription by the cII and cIII proteins
    • Honigman A., Hu S.-L., Szybalski W. Regulation of integration by coliphage λ: activation of int transcription by the cII and cIII proteins. Virology. 92:1979;542-556.
    • (1979) Virology , vol.92 , pp. 542-556
    • Honigman, A.1    Hu, S.-L.2    Szybalski, W.3
  • 15
    • 0028244101 scopus 로고
    • Dissecting the resolution reaction of lambda integrase using suicide Holliday junction substrates
    • Kho S. H., Landy A. Dissecting the resolution reaction of lambda integrase using suicide Holliday junction substrates. EMBO J. 13:1994;2714-2724.
    • (1994) EMBO J. , vol.13 , pp. 2714-2724
    • Kho, S.H.1    Landy, A.2
  • 16
    • 0026537332 scopus 로고
    • Lambda Int protein bridges between higher order complexes at two distant chromosomal loci att L andatt R
    • Kim S., Landy A. Lambda Int protein bridges between higher order complexes at two distant chromosomal loci att L andatt R. Science. 256:1992;198-203.
    • (1992) Science , vol.256 , pp. 198-203
    • Kim, S.1    Landy, A.2
  • 17
    • 0023179984 scopus 로고
    • Homology-dependent interactions in phage λ site-specific recombination
    • Kitts P. A., Nash H. A. Homology-dependent interactions in phage λ site-specific recombination. Nature. 329:1987;346-348.
    • (1987) Nature , vol.329 , pp. 346-348
    • Kitts, P.A.1    Nash, H.A.2
  • 18
    • 0024214884 scopus 로고
    • Bacteriophage lambda site-specific recombination proceeds with a defined order of strand exchanges
    • Kitts P. A., Nash H. A. Bacteriophage lambda site-specific recombination proceeds with a defined order of strand exchanges. J. Mol. Biol. 204:1988;95-107.
    • (1988) J. Mol. Biol. , vol.204 , pp. 95-107
    • Kitts, P.A.1    Nash, H.A.2
  • 19
    • 0007998659 scopus 로고
    • Escherichia coli host factor for site-specific DNA inversion: Cloning and characterization of the fis gene
    • Koch C., Vandekerckhove J., Kahmann R. Escherichia coli host factor for site-specific DNA inversion: Cloning and characterization of the fis gene. Proc. Natl Acad. Sci. USA. 85:1988;4237-4241.
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , pp. 4237-4241
    • Koch, C.1    Vandekerckhove, J.2    Kahmann, R.3
  • 20
    • 0001656001 scopus 로고    scopus 로고
    • Flexibility in DNA recombination: Structure of the λ integrase catalytic core
    • Kwon H. J., Tirumalai R., Landy A., Ellenberger T. Flexibility in DNA recombination: structure of the λ integrase catalytic core. Science. 276:1997;126-131.
    • (1997) Science , vol.276 , pp. 126-131
    • Kwon, H.J.1    Tirumalai, R.2    Landy, A.3    Ellenberger, T.4
  • 21
    • 0024386798 scopus 로고
    • Dynamic, structural and regulatory aspects of lambda site-specific recombination
    • Landy A. Dynamic, structural and regulatory aspects of lambda site-specific recombination. Annu. Rev. Biochem. 58:1989;913-949.
    • (1989) Annu. Rev. Biochem. , vol.58 , pp. 913-949
    • Landy, A.1
  • 22
    • 0027435209 scopus 로고
    • Mechanistic and structural complexity in the site-specific recombination pathways of Int and FLP
    • Landy A. Mechanistic and structural complexity in the site-specific recombination pathways of Int and FLP. Curr. Opin. Genet. Dev. 3:1993;699-707.
    • (1993) Curr. Opin. Genet. Dev. , vol.3 , pp. 699-707
    • Landy, A.1
  • 23
    • 0021714343 scopus 로고
    • Purification and properties of Int-h, a variant protein involved in site-specific recombination by bacteriophage λ
    • Lange-Gustafson B. J., Nash H. A. Purification and properties of Int-h, a variant protein involved in site-specific recombination by bacteriophage λ J. Biol. Chem. 259:1984;12724-12732.
    • (1984) J. Biol. Chem. , vol.259 , pp. 12724-12732
    • Lange-Gustafson, B.J.1    Nash, H.A.2
  • 24
    • 0018883538 scopus 로고
    • Int -h: An int mutation of phage λ that enhances site-specific recombination
    • Miller H. I., Mozola M. A., Friedman D. I. int -h: an int mutation of phage λ that enhances site-specific recombination. Cell. 20:1980;721-729.
    • (1980) Cell , vol.20 , pp. 721-729
    • Miller, H.I.1    Mozola, M.A.2    Friedman, D.I.3
  • 25
  • 26
    • 0026008164 scopus 로고
    • A switch in the formation of alternative DNA loops modulates λ site-specific recombination
    • Moitoso de Vargas L., Landy A. A switch in the formation of alternative DNA loops modulates λ site-specific recombination. Proc. Natl Acad. Sci. USA. 88:1991;588-592.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 588-592
    • Moitoso De Vargas, L.1    Landy, A.2
  • 27
    • 0024295418 scopus 로고
    • Autonomous DNA binding domains of λ integrase recognize different sequence families
    • Moitoso de Vargas L., Pargellis C. A., Hasan N. M., Bushman E. W., Landy A. Autonomous DNA binding domains of λ integrase recognize different sequence families. Cell. 54:1988;923-929.
    • (1988) Cell , vol.54 , pp. 923-929
    • Moitoso De Vargas, L.1    Pargellis, C.A.2    Hasan, N.M.3    Bushman, E.W.4    Landy, A.5
  • 28
    • 0024340762 scopus 로고
    • DNA looping generated by the DNA-bending protein IHF and the two domains of λ integrase
    • Moitoso de Vargas L., Kim S., Landy A. DNA looping generated by the DNA-bending protein IHF and the two domains of λ integrase. Science. 244:1989;1457-1461.
    • (1989) Science , vol.244 , pp. 1457-1461
    • Moitoso De Vargas, L.1    Kim, S.2    Landy, A.3
  • 29
    • 0000078911 scopus 로고    scopus 로고
    • Site-specific recombination: Integration, excision, resolution, and inversion of defined DNA segments
    • F. C. et al. Neidhardt. Washington: ASM Press
    • Nash H. A. Site-specific recombination: integration, excision, resolution, and inversion of defined DNA segments. Neidhardt F. C. et al. Escherichia coli and Salmonella: Cellular and Molecular Biology. 1996;2363-2376 ASM Press, Washington.
    • (1996) Escherichia Coli and Salmonella: Cellular and Molecular Biology , pp. 2363-2376
    • Nash, H.A.1
  • 30
    • 0024463676 scopus 로고
    • Heteroduplex substrates for bacteriophage lambda site-specific recombination: Cleavage and strand transfer products
    • Nash H. A. Heteroduplex substrates for bacteriophage lambda site-specific recombination: cleavage and strand transfer products. EMBO J. 8:1989;3523-3533.
    • (1989) EMBO J. , vol.8 , pp. 3523-3533
    • Nash, H.A.1
  • 31
    • 0023667024 scopus 로고
    • Site-specific recombination intermediates trapped with suicide substrates
    • Nunes-Düby S. E., Matsumoto L., Landy A. Site-specific recombination intermediates trapped with suicide substrates. Cell. 50:1987;779-788.
    • (1987) Cell , vol.50 , pp. 779-788
    • Nunes-Düby, S.E.1    Matsumoto, L.2    Landy, A.3
  • 32
    • 0024431718 scopus 로고
    • Half- att site substrates reveal the homology independence and minimal protein requirements for productive synapsis in λ excisive recombination
    • Nunes-Düby S. E., Matsumoto L., Landy A. Half- att site substrates reveal the homology independence and minimal protein requirements for productive synapsis in λ excisive recombination. Cell. 59:1989;197-206.
    • (1989) Cell , vol.59 , pp. 197-206
    • Nunes-Düby, S.E.1    Matsumoto, L.2    Landy, A.3
  • 34
    • 0029240229 scopus 로고
    • Swapping DNA strands and sensing homology without branch migration in λ site-specific recombination
    • Nunes-Düby S. E., Azaro M., Landy A. Swapping DNA strands and sensing homology without branch migration in λ site-specific recombination. Curr. Biol. 5:1995;139-148.
    • (1995) Curr. Biol. , vol.5 , pp. 139-148
    • Nunes-Düby, S.E.1    Azaro, M.2    Landy, A.3
  • 35
    • 0031551575 scopus 로고    scopus 로고
    • Sensing homology and the strand swapping step in λ excisive recombination
    • Nunes-Düby S. E., Yu D., Landy A. Sensing homology and the strand swapping step in λ excisive recombination. J. Mol. Biol. 272:1997;493-508.
    • (1997) J. Mol. Biol. , vol.272 , pp. 493-508
    • Nunes-Düby, S.E.1    Yu, D.2    Landy, A.3
  • 36
    • 0038659759 scopus 로고    scopus 로고
    • Similarities and differences among 105 members of the Int family of site-specific recombinases
    • Nunes-Düby S. E., Tirumalai R. S., Kwon H. J., Ellenberger T., Landy A. Similarities and differences among 105 members of the Int family of site-specific recombinases. Nucl. Acids Res. 26:1998;391-406.
    • (1998) Nucl. Acids Res. , vol.26 , pp. 391-406
    • Nunes-Düby, S.E.1    Tirumalai, R.S.2    Kwon, H.J.3    Ellenberger, T.4    Landy, A.5
  • 37
    • 0029083699 scopus 로고
    • Characterization of the interaction between the Lambda intasome and att B
    • Patsey R. L., Bruist M. L. Characterization of the interaction between the Lambda intasome and att B. J. Mol. Biol. 252:1995;47-58.
    • (1995) J. Mol. Biol. , vol.252 , pp. 47-58
    • Patsey, R.L.1    Bruist, M.L.2
  • 38
    • 0023022809 scopus 로고
    • The interaction of recombination proteins with supercoiled DNA: Defining the role of supercoiling in lambda integrative recombination
    • Richet E., Abcarian P., Nash H. A. The interaction of recombination proteins with supercoiled DNA: defining the role of supercoiling in lambda integrative recombination. Cell. 46:1986;1011-1021.
    • (1986) Cell , vol.46 , pp. 1011-1021
    • Richet, E.1    Abcarian, P.2    Nash, H.A.3
  • 39
    • 0023854278 scopus 로고
    • Synapsis of attachment sites during lambda integrative recombination involves capture of a naked DNA by a protein-DNA complex
    • Richet E., Abcarian P., Nash H. A. Synapsis of attachment sites during lambda integrative recombination involves capture of a naked DNA by a protein-DNA complex. Cell. 52:1988;9-17.
    • (1988) Cell , vol.52 , pp. 9-17
    • Richet, E.1    Abcarian, P.2    Nash, H.A.3
  • 40
    • 0027173542 scopus 로고
    • Site-specific genetic recombination: Hips, flips, and flops
    • Sadowski P. D. Site-specific genetic recombination: hips, flips, and flops. FASEB J. 7:1993;760-767.
    • (1993) FASEB J. , vol.7 , pp. 760-767
    • Sadowski, P.D.1
  • 41
    • 0027422131 scopus 로고
    • Synaptic intermediates in bacteriophage lambda site-specific recombination: Integrase can align pairs of attachment sites
    • Segall A. M., Nash H. A. Synaptic intermediates in bacteriophage lambda site-specific recombination: integrase can align pairs of attachment sites. EMBO J. 12:1993;4567-4576.
    • (1993) EMBO J. , vol.12 , pp. 4567-4576
    • Segall, A.M.1    Nash, H.A.2
  • 42
    • 0030133847 scopus 로고    scopus 로고
    • Architectural flexibility in lambda site-specific recombination: Three alternate conformations channel the att L site into three distinct pathways
    • Segall A. M., Nash H. A. Architectural flexibility in lambda site-specific recombination: three alternate conformations channel the att L site into three distinct pathways. Genes Cells. 1:1996;453-463.
    • (1996) Genes Cells , vol.1 , pp. 453-463
    • Segall, A.M.1    Nash, H.A.2
  • 45
    • 0014588869 scopus 로고
    • Characteristics of some multiply recombination-deficient strains of Escherichia coli
    • Willetts N. S., Clark A. J. Characteristics of some multiply recombination-deficient strains of Escherichia coli. J. Bacteriol. 100:1969;231-239.
    • (1969) J. Bacteriol. , vol.100 , pp. 231-239
    • Willetts, N.S.1    Clark, A.J.2
  • 46
    • 0030911599 scopus 로고    scopus 로고
    • Genetic analysis of second-site revertants of bacteriophage λ integrase mutants
    • Wu Z., Gumport R. I., Gardner J. F. Genetic analysis of second-site revertants of bacteriophage λ integrase mutants. J. Bacteriol. 179:1997;4030-4038.
    • (1997) J. Bacteriol. , vol.179 , pp. 4030-4038
    • Wu, Z.1    Gumport, R.I.2    Gardner, J.F.3
  • 47
    • 0029082073 scopus 로고
    • Identifying determinants of recombination specificity: Construction and characterization of chimeric bacteriophage integrases
    • Yagil E., Dorgai L., Weisberg R. Identifying determinants of recombination specificity: construction and characterization of chimeric bacteriophage integrases. J. Mol. Biol. 252:1995;163-177.
    • (1995) J. Mol. Biol. , vol.252 , pp. 163-177
    • Yagil, E.1    Dorgai, L.2    Weisberg, R.3
  • 48
    • 0031573477 scopus 로고    scopus 로고
    • Site-specific recombination in plane view
    • Yang W., Mizuuchi K. Site-specific recombination in plane view. Structure. 5:1997;1401-1406.
    • (1997) Structure , vol.5 , pp. 1401-1406
    • Yang, W.1    Mizuuchi, K.2


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