A genome scan for loci associated with aerobic running capacity in rats

Genomics

Volumn 80, Issue 1, 2002, Pages 13-20

  Ways, Justin A ^a   Cicila, George T ^a   Garrett, Michael R ^a   Koch, Lauren Gerard ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

Gene; Inbred; Linkage analysis; Models; Oxygen; QTL

Indexed keywords

OXYGEN; PROTEIN; MICROSATELLITE DNA;

ALLELE; ANIMAL EXPERIMENT; ARTICLE; CHROMOSOME 16; CHROMOSOME 3; ENERGY TRANSFER; GENETIC LINKAGE; GENOME; GENOTYPE; INBRED STRAIN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; RAT; TREADMILL EXERCISE; ANIMAL; BODY WEIGHT; ENDURANCE; GENETIC POLYMORPHISM; GENETICS; HEART; HISTOLOGY; MALE; ORGAN SIZE; OXYGEN CONSUMPTION; RUNNING;

ANIMALIA; RODENTIA;

ANIMALS; BODY WEIGHT; HEART; MALE; MICROSATELLITE REPEATS; ORGAN SIZE; OXYGEN CONSUMPTION; PHENOTYPE; PHYSICAL CONDITIONING, ANIMAL; PHYSICAL ENDURANCE; POLYMORPHISM, GENETIC; QUANTITATIVE TRAIT LOCI; RATS; RUNNING;

EID: 0036296843     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.2002.6797     Document Type: Article

References (45)

1. The evolution of metabolic cycles
2. Aerobic performance in brothers, dizygotic and monozygotic twins
3. Heritability of adaptive variation
4. Changes in physical fitness and changes in mortality
5. Genomics, genes, and environmental interaction: The role of exercise
6. Genomic scan for maximal oxygen uptake and its response to training in the HERITAGE family study
7. Finding the molecular basis of quantitative traits: Successes and pitfalls
8. Spectrum of aerobic endurance running performance in eleven inbred strains of rats
9. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
10. Functional genomics and rat models
11. Genetic analysis of inherited hypertension in the rat
12. Artificial selection for intrinsic aerobic endurance running capacity in rats
13. Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps
14. Accuracy of mapping quantitative trait loci in autogamous species
15. A simple method to calculate resolving power and confidence interval of QTL map location
16. DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene
17. Evidence of LPL gene-exercise interaction for body fat and LPL activity: The HERITAGE Family Study
18. Quantitative trait loci influencing cholesterol and phospholipid phenotypes map to chromosomes that contain genes regulating blood pressure in the spontaneously hypertensive rat
19. A genetic map of the rat derived from recombinant inbred strains
20. Strategies and potential molecular targets for obesity treatment
21. Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity
22. Chromosomal localization of lipolytic enzymes in the mouse: Pancreatic lipase, colipase, hormone-sensitive lipase, hepatic lipase, and carboxyl ester lipase
23. Nuclear receptors and lipid physiology: Opening the X-file
24. Roles of PPARs in health and disease
25. Muscular exercise, lactic acid, and the supply and utilization of oxygen
26. Cardiovascular response to treadmill exercise in untrained rats
27. Determination of metabolic and heart rate responses of rats to treadmill exercise
28. Cardiac performance in inbred rat genetic models of low and high running capacity
29. Phenotypic differences in cardiovascular regulation in inbred rat models of aerobic capacity
30. Genetic mapping of quantitative trait loci influencing left ventricular mass in rats
31. Blood pressure and survival of a chromosome 7 congenic strain derived from Dahl rats
32. Genomic scan and congenic strains for blood pressure QTL using Dahl salt-sensitive rats
33. Animal genetic models for complext traits of physical capacity
34. Construction of a double congenic strain to prove an epistatic interaction on blood pressure between rat chromosomes 2 and 10
35. Cosegregation of blood pressure with angiotensin converting enzyme and atrial natriuretic peptide receptor using Dahl salt-sensitive rats
36. The respective roles of longevity and genetic specificity in the occurrence of spontaneous tumors in the hybrids between two inbred lines of rats
37. Quantitative studies on the behavior of sensitized lymphocytes in vitro
38. Heritability of treadmill running endurance in rats
39. A high-density integrated genetic linkage and radiation hybrid map of the laboratory rat
40. A radiation hybrid map of the rat genome containing 5,255 markers
41. Selective genotyping for determination of linkage between a marker locus and a quantitative trait locus
42. Overview of QTL mapping software and introduction to Map Manager QT
43. A simple regression method for mapping quantitative trait loci in line crosses using flanking markers
44. Empirical threshold values for quantitative trait mapping