Blood pressure and survival of a Chromosome 7 congenic strain bred from Dahl rats

Mammalian Genome

Volumn 8, Issue 12, 1997, Pages 896-902

  Cicila, George T ^a   Dukhanina, Oksana I ^a   Kurtz, Theodore W ^b   Walder, Roxanne ^c   Garrett, Michael R ^a   Dene, Howard ^a   Rapp, John P ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

STEROID 11BETA MONOOXYGENASE;

ANIMAL; ARTICLE; BLOOD PRESSURE; CHEMICALLY INDUCED DISORDER; CHROMOSOME MAP; CONGENITAL ADRENAL HYPERPLASIA; CROSS BREEDING; FEMALE; GENETIC LINKAGE; GENETICS; HEART MUSCLE; HYPERTENSION; LIFE TABLE; LONGEVITY; MALE; ORGAN SIZE; PATHOLOGY; QUANTITATIVE TRAIT; RAT; RAT STRAIN; SALT INTAKE; SEX DIFFERENCE;

ADRENAL HYPERPLASIA, CONGENITAL; ANIMALS; BLOOD PRESSURE; CHROMOSOME MAPPING; CROSSES, GENETIC; FEMALE; HYPERTENSION; LIFE TABLES; LOD SCORE; LONGEVITY; MALE; MYOCARDIUM; ORGAN SIZE; QUANTITATIVE TRAIT, HERITABLE; RATS; RATS, INBRED STRAINS; SEX FACTORS; SODIUM CHLORIDE, DIETARY; STEROID 11-BETA-HYDROXYLASE;

ANIMALIA;

EID: 0031539265     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003359900607     Document Type: Article

References (39)

1. Blin N, Stafford DW (1976) Isolation of high molecular weight DNA. Nucleic Acids Res 3, 2303-2308
2. Bunag R, Butterfield J (1982) Tail cuff blood pressure measurement without external preheating in awake rats. Hypertension 4, 898-903
3. Cicila GT, Rapp JP, Wang J-M, St. Lezin E, Ng SC, Kurtz TW (1993) Linkage of 11β-hydroxylase mutations with altered steroid biosynthesis and blood pressure in the Dahl rat. Nature Genet 3, 346-353
4. Cicila GT, Rapp JP, Bloch KD, Kurtz TW, Pravenec M, Kren V, Hong CC, Quertermous T, Ng SC (1994) Cosegregation of the endothelin-3 locus with blood pressure and relative heart weight in inbred Dahl rats. J Hypertens 12, 643-650
5. Cover CM, Wang J-M, St. Lezin E, Kurtz TW, Mellon SH (1995) Molecular variants in the P450c11AS gene as determinants of aldosterone activity in the Dahl rat model of hypertension. J Biol Chem 270, 16555-16560
6. Dahl LK, Heine M, Tassinari L (1962) Effects of chronic excess salt ingestion: evidence that genetic factors play an important role in the susceptibility to experimental hypertension. J Exp Med 115, 1173-1190
7. Deng AY, Dene H, Pravenec M, Rapp JP (1994) Genetic mapping of two new blood pressure quantitative trait loci in the rat by genotyping endothelin system genes. J Clin Invest 93, 2701-2709
8. Du Y, Remmers EF, Zha H, Goldmuntz EA, Szpirer J, Szpirer C, Wilder RC (1995) A genetic map of microsatellite markers on rat Chromosome 7. Mamm Genome 6, 295-298
9. Elston RC (1997) Algorithms and inferences: the challenge of multifactorial diseases. Am J Hum Genet 60, 255-262
10. Frankel WN, Schork NJ (1996) Who's afraid of epistasis? Nature Genet 14, 371-373
11. Friedman M, Freed C (1949) Microphonic manometer for indirect determination of systolic blood pressure in the rat. Proc Soc Exp Biol Med 70, 670-672
12. Imai M, Shimada H, Okada Y, Matsushima-Hibiya Y, Ogishima T, Ishimura Y (1990) Molecular cloning of a cDNA encoding aldosterone synthase cytochrome P-450 in rat adrenal cortex. FEBS Lett 263, 299-302
13. Jacob HJ, Brown DM, Bunker RK, Daly MJ, Dzau VJ, Goodman A, Koike G, Kren V, Kurtz T, Lernmark Å, Levan G, Mao L-P, Pettersson A, Pravenec M, Simon JS, Szpirer C, Szpirer J, Trolliet MR, Winer ES, Lander ES (1995) A genetic linkage map of the laboratory rat, Rattus norvegicus. Nature Genet 9, 63-69
14. Kosambi DD (1944) The estimation of map distances from recombination values. Ann Eugen 12, 172-175
15. Lander EP, Botstein D (1989) Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 12, 185-199
16. Lander ES, Kruglyak L (1995) Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nature Genet 11, 241-247
17. Lander ES, Green P, Abrahamson J, Barlow A, Daly MJ, Lincoln SE, Newburg L (1987) MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. Genomics 1, 174-181
18. rd ed
19. rd ed
20. Matsukawa N, Nonaka Y, Ying Z, Higaki J, Ogihara T, Okamoto M (1990) Molecular cloning and expression of cDNAs encoding rat aldosterone synthase: variants of cytochrome P45011b. Biochem Biophys Res Commun 169, 245-252
21. Matsukawa N, Nonaka Y, Higaki J, Nagano M, Mikami HTO, Okamoto M (1993) Dahl's salt-resistant normotensive rat has mutations in cytochrome P450(11b), but the salt-sensitive hypertensive rat does not. J Biol Chem 268, 9117-9121
22. 11β). J Biol Chem 264, 20961-20967
23. Ostle B (1963) Statistics in Research: Basic Concepts and Techniques for Research Workers (Ames, Iowa: Iowa State University Press), pp 199-200
24. Paterson A, Lander E, Lincoln S, Hewitt J, Peterson S, Tanksley S (1988) Resolution of quantitative traits into Mendelian factors using a complete RFLP linkage map. Nature 335, 721-726
25. Rapp JP, Dahl LK (1971) Adrenal steroidogenesis in rats bred for susceptibility and resistance to the hypertensive effect of salt. Endocrinology 88, 52-65
26. Rapp JP, Dahl LK (1972a) Mendelian inheritance of 18 and 11β-steroid hydroxylase activities in the adrenals of rats genetically susceptible or resistant to hypertension. Endocrinology 90, 1435-1446
27. Rapp JP, Dahl LK (1972b) Possible role of 18-hydroxy-deoxycorticosterone in hypertension. Nature 237, 338-339
28. Rapp JP, Dahl LK (1976) Mutant forms of cytochrome P-450 controlling both 18- and 11β-steroid hydroxylation in the rat. Biochemistry 15, 1235-1242
29. Rapp JP, Dene H (1985) Development and characteristics of inbred strains of Dahl salt-sensitive and salt-resistant rats. Hypertension 7, 340-349
30. +-ATPase α1 locus to cosegregate with blood pressure in Dahl rats. J Hypertens 8, 457-462
31. Rapp JP, Deng AY (1995) Detection and positional cloning of blood pressure quantitative trait loci: is it possible? Identifying the genes for genetic hypertension. Hypertension 25, 1121-1128
32. Rapp JP, Wang S-M, Dene H (1989) A genetic polymorphism in the renin gene of Dahl rats cosegregates with blood pressure. Science 243, 542-544
33. Rapp JP, Wang S-M, Dene H (1990) Effect of genetic background on cosegregation of renin alleles and blood pressure in Dahl rats. Am J Hypertens 3, 391-396
34. Rapp JP, Dene H, Dene AY (1994) Seven renin alleles in rats and their effect on blood pressure. J Hypertens 12, 349-355
35. Serikawa T, Kuramoto T, Hilbert P, Mori M, Yamada J, Dubay CJ, Lindpainter K, Ganten D, Guenet JL, Lathrop GM, Beckmann JS (1992) Rat gene mapping using PCR-analyzed microsatellites. Genetics 131, 701-721
36. Sokal RR, Rohlf FJ (1969) Biometry: The Principles and Practice of Statistics in Biological Research (San Francisco: W.H. Freeman), pp 479-480
37. Sunden SL, Businga T, Beck J, McClain A, Gastier JM, Pulido JC, Yandava CN, Brody T, Ghazizadeh J, Weber JL, Duyk GM, Murray JC, Buetow KH, Sheffield VC (1996) Chromosomal assignment of 2900 triand tetranucleotide repeat markers using NIGMS somatic cell hybrid panel 2. Genomics 32, 15-20
38. Witte JS, Elston RC, Schork NJ (1996) Genetic dissection of complex traits. Nature Genet 12, 355-356
39. Zhang Q-Y, Dene H, Deng AY, Garrett MR, Jacob HJ, Rapp JP (1997) Interval mapping and congenic strains for a blood pressure QTL on rat Chromosome 13. Mamm Genome 8, 636-641