메뉴 건너뛰기




Volumn 967, Issue , 2002, Pages 34-42

Sterol regulatory element-binding proteins (SREBPs) as regulators of lipid metabolism: Polyunsaturated fatty acids oppose cholesterol-mediated induction of SREBP-1 maturation

Author keywords

Cholesterol; Gene; Metabolism; Protein; PUFA; SREBP

Indexed keywords

ACYL COENZYME A DESATURASE; CHOLESTEROL; FATTY ACID SYNTHASE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; MESSENGER RNA; POLYUNSATURATED FATTY ACID; STEROL REGULATORY ELEMENT BINDING PROTEIN; TRIACYLGLYCEROL;

EID: 0036291389     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb04261.x     Document Type: Conference Paper
Times cited : (51)

References (34)
  • 1
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane bound transcription factor
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 2
    • 0033544869 scopus 로고    scopus 로고
    • A crucial role of sterol regulatory element-binding protein-1 in the regulation of lipogenic gene expression by polyunsaturated fatty acids
    • (1999) J. Biol. Chem. , vol.274 , pp. 35840-35844
    • Yahagi, N.1    Shimano, H.2    Hasty, A.H.3
  • 4
    • 0032104180 scopus 로고    scopus 로고
    • Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2
    • (1998) J. Clin. Invest. , vol.101 , pp. 2331-2339
    • Horton, J.D.1    Shimomura, I.2    Brown, M.S.3
  • 5
    • 0035424456 scopus 로고    scopus 로고
    • CREating a SCAP-less liver keeps SREBPs pinned in the ER membrane and prevents increased lipid synthesis in response to low cholesterol and high insulin
    • (2001) Genes Dev. , vol.15 , pp. 1873-1878
    • Osborne, T.F.1
  • 6
    • 0034693259 scopus 로고    scopus 로고
    • Sterol regulatory element-binding proteins (SREBPs): Key regulators of nutritional homeostasis and insulin action
    • (2000) J. Biol. Chem. , vol.275 , pp. 32379-32382
    • Osborne, T.F.1
  • 7
    • 0028960739 scopus 로고
    • Structure of human gene encoding sterol regulatory element binding protein-1 (SREBP-1) and localization of SREBP-1 and SREBP-2 to chromosomes 17p11.2 and 22q13
    • (1995) Genomics , vol.25 , pp. 667-673
    • Hua, X.1    Wu, J.2    Goldstein, J.L.3
  • 10
    • 0028225462 scopus 로고
    • SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis
    • (1994) Cell , vol.77 , pp. 53-62
    • Wang, X.1    Sato, R.2    Brown, M.S.3
  • 11
    • 0030604717 scopus 로고    scopus 로고
    • Sterol regulated release of SREBP-2 from cell membrane requires two sequential cleavages, one within a transmembrane segment
    • (1996) Cell , vol.85 , pp. 1037-1046
    • Sakai, J.1    Duncan, E.A.2    Rawson, R.B.3
  • 12
    • 0027190308 scopus 로고
    • Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter: I. Identification of the protein and delineation of its target nucleotide sequence
    • (1993) J. Biol. Chem. , vol.268 , pp. 14490-14496
    • Briggs, M.R.1    Yokoyama, C.2    Wang, X.3
  • 13
    • 0027167918 scopus 로고
    • Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter: II. Purification and characterization
    • (1993) J. Biol. Chem. , vol.268 , pp. 14497-14504
    • Wang, X.1    Briggs, M.R.2    Hua, X.3
  • 14
    • 0033520484 scopus 로고    scopus 로고
    • Fish oil feeding decreases mature sterol regulatory element-binding protein-1 by down-regulation of SREBP-1c mRNA in mouse liver: A possible mechanism for down-regulation of lipogenic enzyme mRNAs
    • (1999) J. Biol. Chem. , vol.274 , pp. 25892-25898
    • Kim, H.-J.1    Takahashi, M.2    Ezaki, O.3
  • 24
    • 0035066651 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid regulation of gene transcription: A molecular mechanism to improve the metabolic syndrome
    • (2001) J. Nutr. , vol.131 , pp. 1129-1132
    • Clarke, S.D.1
  • 25
    • 0013199471 scopus 로고    scopus 로고
    • Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha
    • (1998) Cell , vol.93 , pp. 693-704
    • Peet, D.J.1    Turley, S.D.2    Ma, W.3
  • 26
    • 0034669025 scopus 로고    scopus 로고
    • Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ
    • (2000) Genes Dev. , vol.14 , pp. 2819-2830
    • Repa, J.J.1    Liang, G.2    Ou, J.3
  • 34
    • 0032871502 scopus 로고    scopus 로고
    • Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol
    • (1999) J. Lipid Res. , vol.40 , pp. 1549-1558
    • Ntambi, J.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.