Design and synthesis of novel [60]fullerene derivatives as potential HIV aspartic protease inhibitors

Organic Letters

Volumn 2, Issue 25, 2000, Pages 3955-3957

  Luca Marcorin, Gian ^a   Da Ros, Tatiana ^a   Castellano, Sabrina ^a   Stefancich, Giorgio ^a   Bonin, Irena ^b   Miertus, Stanislav ^b   Prato, Maurizio ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

^b Intl Ctr Sci and High Technol   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; FULLERENE C60; FULLERENE DERIVATIVE; PROTEINASE INHIBITOR;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS;

CARBON; DRUG DESIGN; FULLERENES; HIV PROTEASE INHIBITORS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR;

EID: 0034649734     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol000217y     Document Type: Article

References (15)

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14. We thank Prof. F. Diederich (ETH Zurich) for drawing our attention to this issue.
15. For details on modeling of HIV PR with various inhibitors, see: Nair A. C.; Miertus S.; Tossi A.; Romeo D. Biochem. Biophys. Res. Commun. 1998, 242, 545-551.