Allosteric mechanisms in P450eryF probed with 1-pyrenebutanol, a novel fluorescent substrate

Biochemical and Biophysical Research Communications

Volumn 294, Issue 4, 2002, Pages 806-812

  Davydov, Dmitri R ^a   Kumar, Santosh ^a   Halpert, James R ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

1 Pyrenebutanol; 2 Hydroxypropyl cyclodextrin; Cooperativity; Cytochrome P450eryF; Fluorescence resonance energy transfer; Spin equilibrium; Substrate binding site

Indexed keywords

1 PYRENEBUTANOL; BUTANOL; CYTOCHROME P450; CYTOCHROME P450ERYF; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CHROMATOGRAPHY; ENZYME MECHANISM; FLUOROMETRY; HYDROXYLATION; MOLECULAR INTERACTION; PRIORITY JOURNAL; SPECTROMETRY;

ALLOSTERIC SITE; BINDING SITES; BUTANOLS; CHROMATOGRAPHY, THIN LAYER; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY TRANSFER; FLUORESCENT DYES; KINETICS; MIXED FUNCTION OXYGENASES; MODELS, CHEMICAL; PYRENES; SPECTROMETRY, FLUORESCENCE;

EID: 0036280543     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)00565-X     Document Type: Article

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