Contributions of saturable active secretion, passive transcellular, and paracellular diffusion to the overall transport of furosemide across adenocarcinoma (Caco-2) cells

Journal of Pharmaceutical Sciences

Volumn 91, Issue 4, 2002, Pages 1169-1177

  Flanagan, Shawn D ^a,c   Takahashi, Lpori H ^b   Liu, Xiaoli ^b   Benet, Leslie Z ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b AFFYMAX RESEARCH INSTITUTE   (United States)

^c ELI LILLY AND COMPANY   (United States)

Author keywords

Caco 2; Furosemide; Paracellular; Transcellular; Transporters

Indexed keywords

CALCIUM CHELATING AGENT; EGTAZIC ACID; FUROSEMIDE;

APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CELL MOTILITY; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG DIFFUSION; DRUG ELIMINATION; DRUG PENETRATION; DRUG TRANSPORT; ENERGY; HUMAN; HUMAN CELL; PARAMETER; TIGHT JUNCTION; TRANSCYTOSIS;

EID: 0036279841     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10099     Document Type: Article

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