Gastrointestinal safety of selective COX-2 inhibitors

Current Pharmaceutical Design

Volumn 8, Issue 12, 2002, Pages 1077-1089

  Hawkey, C J ^a   Skelly, M M ^a  

^a QUEEN S MEDICAL CENTRE   (United Kingdom)

Author keywords

Cyclo oxygenase; GI bleeding; Inducible cyclo oxygenase; Misoprostol; NSAIDs; Prostaglandins; Proton pump inhibitor; Ulcers

Indexed keywords

ACETYLSALICYLIC ACID; BICARBONATE; CELECOXIB; CORTICOSTEROID; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; DICLOFENAC; ETODOLAC; IBUPROFEN; INDOMETACIN; MELOXICAM; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NABUMETONE; NAPROXEN; NIMESULIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PIROXICAM; PLACEBO; PROSTAGLANDIN DERIVATIVE; ROFECOXIB;

AGED; ANALGESIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; BACTERIAL INFECTION; CONTROLLED STUDY; DIGESTIVE SYSTEM INJURY; DIGESTIVE SYSTEM ULCER; DOSE RESPONSE; DRUG INDUCED DISEASE; DRUG INHIBITION; DRUG SAFETY; DRUG SELECTIVITY; DYSPEPSIA; GASTROINTESTINAL MUCOSA; HELICOBACTER PYLORI; HUMAN; PRIORITY JOURNAL; RETROSPECTIVE STUDY; REVIEW; RISK FACTOR; UPPER GASTROINTESTINAL TRACT;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARDIOVASCULAR DISEASES; CLINICAL TRIALS; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DIGESTIVE SYSTEM; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTAGLANDINS; SODIUM;

EID: 0036264157     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/1381612023394999     Document Type: Review

References (95)