Toward the design of ribonuclease (RNase) inhibitors: Ion effects on the thermodynamics of binding of 2′-CMP to RNase A

Journal of Pharmacology and Experimental Therapeutics

Volumn 301, Issue 3, 2002, Pages 925-929

  Spencer, Shawn D ^a   Abdul, Oluseyi ^b   Schulingkamp, Robert J ^a   Raffa, Robert B ^c  

^a School of Pharmacy   (Israel)

^b University of Nashville School of Medicine   (United States)

^c TEMPLE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2' CYTIDINE MONOPHOSPHATE; ENZYME INHIBITOR; ION; RIBONUCLEASE A; RIBONUCLEASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CALORIMETRY; DRUG BINDING; DRUG DESIGN; ENTHALPY; ENZYME BINDING; PRIORITY JOURNAL; REACTION ANALYSIS; THERMODYNAMICS;

ANIMALS; BINDING, COMPETITIVE; BUFFERS; CALORIMETRY; CATIONS, DIVALENT; CATIONS, MONOVALENT; CATTLE; CYTIDINE MONOPHOSPHATE; ENZYME INHIBITORS; LIGANDS; RIBONUCLEASE, PANCREATIC; THERMODYNAMICS;

EID: 0036263924     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.301.3.925     Document Type: Article

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