Cyclooxygenase-2 expression in human pancreatic adenocarcinomas

Carcinogenesis

Volumn 21, Issue 2, 2000, Pages 139-146

  Yip Schneider, Michele T ^a   Barnard, Darlene S ^c   Billings, Steven D ^a   Cheng, Liang ^a   Heilman, Douglas K ^b   Lin, Amy ^a   Marshall, Steven J ^a   Crowell, Pamela L ^a   Marshall, Mark S ^a,c   Sweeney, Christopher J ^a  

^a INDIANA UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; INDOMETACIN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN E2; SULINDAC;

ARTICLE; CANCER CELL CULTURE; CELL GROWTH; CLINICAL ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; ONCOGENE K RAS; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL;

EID: 0033963927     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/21.2.139     Document Type: Article

References (37)

1. Landis, S.H., Murray, T., Bolden, S. and Wingo, P.A. (1998) Cancer statistics, 1998. CA Cancer J. Clin., 48, 6-29 [Errata (1998) CA Cancer J. Clin., 48, 192; Errata (1998) CA Cancer J. Clin., 48, 329].
2. Almoguera, C., Shibata, D., Forrester, K., Martin, J., Arnheim, N. and Perucho, M. (1988) Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell, 53, 549-554.
3. Thun, M.J. (1994) Aspirin. NSAIDs, and digestive tract cancers. Cancer Metastasis Rev., 13, 269-277.
4. Giardiello, F.M., Offerhaus, G.J. and DuBois, R.N. (1995) The role of nonsteroidal anti-inflammatory drugs in colorectal cancer prevention. Eur. J. Cancer, 31A, 1071-1076.
5. DeWitt, D.L. and Meade, E.A. (1993) Serum and glucocorticoid regulation of gene transcription and expression of the prostaglandin H synthase-1 and prostaglandin H synthase-2 isozymes. Arch. Biochem. Biophys., 306, 94-102.
6. Hamasaki, Y., Kitzler, J., Hardman, R., Nettesheim, P. and Eling, T.E. (1993) Phorbol ester and epidermal growth factor enhance the expression of two inducible prostaglandin H synthase genes in rat tracheal epithelial cells. Arch. Biochem. Biophys., 304, 226-234.
7. Eberhart, C.E., Coffey, R.J., Radhika, A., Gardiello, F.M., Ferrenbach, S. and DuBois, R.N. (1994) Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology, 107, 1183-1188.
8. Ristimaki, A., Honkanen, N., Jankala, H., Sipponen, P. and Harkonen, M. (1997) Expression of cyclooxygenase-2 in human gastric carcinoma. Cancer Res., 57, 1276-1280.
9. Zimmermann, K.C., Sarbia, M., Weber, A.A., Borchard, F., Gabbert, H.E. and Schror, K. (1999) Cyclooxygenase-2 expression in human esophageal carcinoma. Cancer Res., 59, 198-204.
10. Wolff, H., Saukkonen, K., Anttila, S., Karjalainen, A., Vainio, H. and Ristimaki, A. (1998) Expression of cyclooxygenase-2 in human lung carcinoma. Cancer Res., 58, 4997-5001.
11. Tucker, O.N., Dannenberg, A.J., Yang, E.K., Zhang, F., Teng, L., Daly, J.M., Soslow, R.A., Masferrer, J.L., Woerner, B.M., Koki, A.T. and Fahey, T.J. (1999) Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer. Cancer Res., 59, 987-990.
12. Tsujii, M., Kawano, S. and DuBois, R.N. (1997) Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential. Proc. Natl Acad. Sci. USA, 94, 3336-3340.
13. Tsujii, M. and DuBois, R.N. (1995) Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell, 83, 493-501.
14. Tsujii, M., Kawano, S., Tsuji, S., Sawaoka, H., Hori, M. and Dubois, R.N. (1998) Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell, 93, 705-716.
15. Oshima, M., Dinchuk, J.E., Kargman, S.L., Oshima, H., Hancock, B., Kwong, E., Trzaskos, J.M., Evans, F. and Taketo, M.M. (1996) Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell, 87, 803-809.
16. Sheng, G.G., Shao, J., Sheng, H., Hooton, E.B., Isakson, P.C., Morrow, J.D., Coffey, R.J.Jr. DuBois, R.N. and Beauchamp, R.D. (1997) A selective cyclooxygenase 2 inhibitor suppresses the growth of H-ras-transformed rat intestinal epithelial cells [see comments]. Gastroenterology, 113, 1883-1891.
17. Subbaramaiah, K., Telang, N., Ramonetti, J.T., Araki, R., DeVito, B., Weksler, B.B. and Dannenberg, A.J. (1996) Transcription of cyclooxygenase-2 is enhanced in transformed mammary epithelial cells. Cancer Res., 56, 4424-4429.
18. Heasley, L.E., Thaler, S., Nicks, M., Price, B., Skorecki, K. and Nemenoff, R.A. (1997) Induction of cytosolic phospholipase A2 by oncogenic Ras in human non-small cell lung cancer. J. Biol. Chem., 272, 14501-14504.
19. Hsu, S.M., Raine, L. and Fanger, H. (1981) Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase technique: a comparison between ABC and unlabeled antibody procedures. J. Histochem. Cytochem., 29, 577-580.
20. Sumi, S., Beauchamp, R.D., Townsend, C.M.Jr, Pour, P.M., Ishizuka, J. and Thompson, J.C. (1994) Lovastatin inhibits pancreatic cancer growth regardless of RAS mutation. Pancreas, 9, 657-661.
21. Konishi, N., Enomoto, T., Buzard, G., Ohshima, M. and Ward, J.M. (1992) K-ras activation and ras p21 expression in latent prostatic carcinoma in Japanese men. Cancer, 69, 2293-2299.
22. Mangold, K.A., Hubchak, S., Mangino, M.M., Laconi, S. and Scarpelli, D.G. (1994) In vitro carcinogenesis of hamster pancreatic duct cells: cellular and molecular alterations. Carcinogenesis, 15, 1979-1984.
23. Stayrook, K.R., McKinzie, J.H., Barbhaiya, L.H. and Crowell, P.L. (1998) Effects of the antitumor agent perillyl alcohol on H-Ras vs. K-Ras farnesylation and signal transduction in pancreatic cells. Anticancer Res., 18, 823-828.
24. Riese, J., Hoff, T., Nordhoff, A., DeWitt, D.L., Resch, K. and Kaever, V. (1994) Transient expression of prostaglandin endoperoxide synthase-2 during mouse macrophage activation. J. Leukoc. Biol., 55, 476-482.
25. Berrozpe, G., Schaeffer, J., Peinado, M.A., Real, F.X. and Perucho, M. (1994) Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer. Int. J. Cancer, 58, 185-191.
26. Yip-Schneider, M.T., Lin, A., Barnard, D., Sweeney, C.J. and Marshall, M.S. (1999) Lack of elevated MAP kinase (Erk) activity in pancreatic carcinomas despite oncogenic K-ras expression. Int. J. Oncol., 15, 271-279.
27. Meade, E.A., Smith, W.L. and DeWitt, D.L. (1993) Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs. J. Biol. Chem., 268, 6610-6614.
28. Futaki, N., Takahashi, S., Yokoyama, M., Arai, I., Higuchi, S. and Otomo, S. (1994) NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro. Prostaglandins, 47, 55-59.
29. Lee, S.H., Soyoola, E., Chanmugam, P., Hart, S., Sun, W., Zhong, H., Liou, S., Simmons, D. and Hwang, D. (1992) Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide. J. Biol. Chem., 267, 25934-25938.
30. Kiyohara, H., Egami, H., Kako, H., Shibata, Y., Murata, K., Ohshima, S., Sei, K., Suko, S., Kurano, R. and Ogawa, M. (1993) Immunohistochemical localization of group II phospholipase A2 in human pancreatic carcinomas. Int. J. Pancreatol., 13, 49-57.
31. Takahashi, M., Furukawa, F., Toyoda, K., Sato, H., Hasegawa, R., Imaida, K. and Hayashi, Y. (1990) Effects of various prostaglandin synthesis inhibitors on pancreatic carcinogenesis in hamsters after initiation with N-nitrosobis(2-oxopropyl)amine. Carcinogenesis, 11, 393-395.
32. Sheng, H., Williams, C.S., Shao, J. Liang, P., DuBois, R.N. and Beauchamp, R.D. (1998) Induction of cyclooxygenase-2 by activated Haras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway. J. Biol. Chem., 273, 22120-22127.
33. Dean, J.L., Brook, M., Clark, A.R. and Saklatvala, J. (1999) p38 mitogenactivated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes. J. Biol. Chem., 274, 264-269.
34. Schmedtje, J.F.Jr, Ji, Y.S., Liu, W.L., DuBois, R.N. and Runge, M.S. (1997) Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cells. J. Biol. Chem., 272, 601-608.
35. Elder, D.J.E., Halton, D.E., Hague, A. and Paraskeva, C. (1997) Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: independence from COX-2 protein expression. Clin. Cancer Res., 3, 1679-1683.
36. Piazza, G.A., Alberts, D.S., Hixson, L.J., Paranka, N.S., Li, H., Finn, T., Bogert, C., Guillen, J.M., Brendel, K., Gross, P.H., Sperl, G., Ritchie, J., Burt, R.W., Ellsworth, L., Ahnen, D.J. and Pamukcu, R. (1997) Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels. Cancer Res., 57, 2909-2915.
37. Zhang, X., Morham, S.G., Langenbach, R. and Young, D.A. (1999) Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts. J. Exp. Med., 190, 451-459.