A collaborative screening program for the discovery of inhibitors of HCV NS2/3 cis-cleaving protease activity

Journal of Biomolecular Screening

Volumn 7, Issue 2, 2002, Pages 149-154

  Whitney, Mike ^a   Stack, Jeffrey H ^a   Darke, Paul L ^b   Zheng, Wei ^b   Terzo, Joe ^b   Inglese, Jim ^b   Strulovicil, Berta ^b   Kuo, Lawrence C ^b   Pollok, Brian A ^a  

^a Aurora Biosciences Corporation   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; BETA LACTAMASE; HYBRID PROTEIN; NONSTRUCTURAL PROTEIN 3; PROTEIN NS2; PROTEINASE; UBIQUITIN; UNCLASSIFIED DRUG;

ARTICLE; CELL ASSAY; CONTROLLED STUDY; DRUG SCREENING; ENZYME ACTIVITY; ENZYME DEGRADATION; GENE INSERTION; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; MUTANT; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STABILITY; REPORTER GENE;

AUTOMATION; CYCLOHEXIMIDE; CYSTEINE ENDOPEPTIDASES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; GENES, REPORTER; HEPACIVIRUS; HUMANS; JURKAT CELLS; MODELS, GENETIC; MUTATION; PLASMIDS; PROTEASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY; PROTEIN SYNTHESIS INHIBITORS; RECOMBINANT FUSION PROTEINS;

HEPATITIS C VIRUS;

EID: 0036256391     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1089/10870570252906611     Document Type: Article

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