Changes in BRCA1 and BRCA2 expression produced by chemotherapeutic agents in human breast cancer cells

International Journal of Biochemistry and Cell Biology

Volumn 34, Issue 8, 2002, Pages 950-957

  Su, Jiangfeng ^a   Ciftci, Kadriye ^a  

^a TEMPLE UNIVERSITY   (United States)

Author keywords

Adriamycin; BRCA1 and BRCA2; Breast cancer; Cell cycle; Chemotherapeutic agents

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; CAMPTOTHECIN; DOXORUBICIN; MESSENGER RNA; METHOTREXATE; MITOMYCIN C;

ARTICLE; BREAST CARCINOMA; BREAST EPITHELIUM; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER GROWTH; CELL CYCLE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; EPITHELIUM CELL; FEMALE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; PROTEIN DETERMINATION; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; CAMPTOTHECIN; CELL CYCLE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DOXORUBICIN; FEMALE; HUMANS; METHOTREXATE; MITOMYCIN; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 0036252668     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(02)00016-X     Document Type: Article

References (17)

1. Identifying tumor-suppressor genes in human colorectal cancer
2. Characteristics of small breast and/or ovarian cancer families with germline mutations in BRCA1 and BRCA2
3. Genetic linkage analysis in familial breast and ovarian cancer: Results from 214 families
4. Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families
5. Growth retardation and tumor inhibition by BRCA1
6. Breast cancer susceptibility genes BRCA1 and BRCA2
7. Changes in BRC2 expression during progression of the cell cycle
8. Association of BRCA1 with Rad51 in mitotic and meiotic cells
9. Dynamic changes of BRCA1 subnuclear location and phosphorylation state are inhibited by DNA damage
10. Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents
11. Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking BRCA2
12. Permanent cell cycle arrest in asynchronously proliferating normal human fibroblasts treated with doxorubicin or etoposide but not camptothecin
13. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
14. Treatment of breast cancer
15. DNA damage responses: p53 induction, cell cycle perturbations, and apoptosis