A new ditriazine inhibitor of NF-κB modulates chronic inflammation and angiogenesis

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 365, Issue 5, 2002, Pages 357-364

  Rioja, Inmaculada ^a,b,c   Terencio, Carmen M ^a,b,c   Ubeda, Amalia ^a,b,c   Riguera, Ricardo ^a,b,c   Quintela, José M ^a,b,c   Alcaraz, José M ^a,b,c  

^a UNIVERSITY OF VALENCIA   (Spain)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^c UNIVERSITY OF A CORUÑA   (Spain)

Author keywords

Angiogenesis; Chronic inflammation; Cyclo oxygenase 2; Cytokines; Nuclear factor B

Indexed keywords

4,10 DICHLOROPYRIDO[5,6:4,5]THIENO[3,2 D':3,2 D] 1,2,3 DITRIAZINE; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; PROSTAGLANDIN E2; TRIAZINE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADJUVANT ARTHRITIS; ANGIOGENESIS; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHRONIC INFLAMMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DNA BINDING; DRUG EFFECT; DRUG MECHANISM; FEMALE; GRANULOMA; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RAT;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTHRITIS, EXPERIMENTAL; CELL LINE; CELL NUCLEUS; CHRONIC DISEASE; CYCLOOXYGENASE 2; DINOPROSTONE; DNA; DNA-BINDING PROTEINS; FEMALE; GRANULOMA; I-KAPPA B PROTEINS; INTERLEUKIN-1; ISOENZYMES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NEOVASCULARIZATION, PATHOLOGIC; NF-KAPPA B; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; TRIAZINES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036250254     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-002-0544-z     Document Type: Article

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