Expression of BRCA1 and BRCA2 in different tumor cell lines with various growth status

Clinica Chimica Acta

Volumn 320, Issue 1-2, 2002, Pages 101-110

  Vissac, Cécile ^a   De Latour, Monique Peffault ^a   Communal, Yves ^a   Bignon, Yves Jean ^a   Bernard Gallon, Dominique J ^a  

^a CENTRE JEAN PERRIN   (France)

Author keywords

BRCA1; BRCA2; Flow cytometry analysis; Immunohistochemistry; Real time quantitative RT PCR

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; M PROTEIN; MESSENGER RNA;

ARTICLE; BRCA2 GENE; CANCER GROWTH; CELL ASSAY; CELL CYCLE; CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; FLOW CYTOMETRY; GENE; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; TUMOR CELL;

BRCA1 PROTEIN; BRCA2 PROTEIN; EXONS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BRCA1; GENES, BRCA2; HUMANS; IMMUNOHISTOCHEMISTRY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 0036240172     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-8981(02)00055-4     Document Type: Article

References (28)

1. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
2. Identification of the breast cancer susceptibility gene BRCA2
3. A collaborative survey of 80 mutations in the BRCA1 breast and ovarian cancer susceptibility gene. Implications for presymptomatic testing and screening
4. Mutation analysis in the BRCA2 gene in primary breast cancers
5. BRCA2 germline mutations in male breast cancer cases and breast cancer families
6. Mutation analysis of the BRCA2 gene in 49 site-specific breast cancer families
7. BRCA2 mutations in primary breast and ovarian cancers
8. Low incidence of BRCA2 mutations in breast carcinoma and other cancers
9. Cell cycle control of BRCA2
10. Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells
11. Developmental expression of Brca2 colocalizes with Brca1 and is associated with proliferation and differentiation in multiple tissues
12. Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-delta11b
13. Increased level of exon 12 alternatively spliced BRCA2 transcripts in tumor breast tissue compared with normal tissue
14. A human cell line from a pleural effusion derived from a breast carcinoma
15. Breast tumor cell lines from pleural effusions
16. Heterotransplantation of human malignant tumors in "nude" thymusless mice. II. Malignant tumors induced by injection of cell cultures derived from human solid tumors
17. Absence of HeLa cell contamination in 169 cell lines derived from human tumors
18. N,N-dimethylformamide-induced alteration of cell culture characteristics and loss of tumorigenicity in cultured human colon carcinoma cells
19. Location of BRCA1 in human breast and ovarian cancer cells
20. Transcriptional activation functions in BRCA2
21. Novel approach to quantitative polymerase chain reaction using real-time detection: Application to the detection of gene amplification in breast cancer
22. Localization of BRCA1 and a splice variant identifies the nuclear localization signal
23. Analysis of cell cycle-related Ki-67 and p120 expression by flow cytometric BrdUrd-Hoechst/7AAD and immunolabeling technique
24. Assessment of cell proliferation by means of an enzyme-linked immunosorbent assay based on the detection of the Ki-67 protein
25. Localization of human BRCA1 and BRCA2 in non-inherited colorectal carcinomas and matched normal mucosas
26. Real-time PCR quantification of full-length and exon 11 spliced BRCA1 transcripts in human breast cancer cell lines
27. Characterization of functional messenger RNA splice variants of BRCA1 expressed in nonmalignant and tumor-derived breast cells
28. BRCA1, BRCA2, and Rad51 operate in a common DNA damage response pathway