Complementation of vaccinia virus lacking the double-stranded RNA-binding protein gene E3L by human cytomegalovirus

Journal of Virology

Volumn 76, Issue 10, 2002, Pages 4912-4918

  Child, Stephanie J ^a   Jarrahian, Sohail ^a   Harper, Victoria M ^a   Geballe, Adam P ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DOUBLE STRANDED RNA; GANCICLOVIR; INITIATION FACTOR; INITIATION FACTOR 2; RIBONUCLEASE; STRUCTURAL PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE DELETION; GENE EXPRESSION; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; VACCINIA VIRUS; VIRION; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

2',5'-OLIGOADENYLATE SYNTHETASE; ANIMALS; CYTOMEGALOVIRUS; EIF-2 KINASE; EUKARYOTIC INITIATION FACTOR-2; GANCICLOVIR; GENE EXPRESSION; GENETIC COMPLEMENTATION TEST; HUMANS; MUTATION; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; RNA, ANTISENSE; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; TUMOR CELLS, CULTURED; ULTRAVIOLET RAYS; VACCINIA VIRUS; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 0036239936     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.76.10.4912-4918.2002     Document Type: Article

References (42)

1. Reversal of the interferon-sensitive phenotype of a vaccinia virus lacking E3L by expression of the reovirus S4 gene
2. Host-range restriction of vaccinia virus E3L-specific deletion mutants
3. -mutant viruses
4. Translational inhibition by cytomegalovirus transcript leaders
5. Engagement of the cellular receptor for glycoprotein B of human cytomegalovirus activates the interferon-responsive pathway
6. Both carboxy- and amino-terminal domains of the vaccinia virus interferon resistance gene, E3L, are required for pathogenesis in a mouse model
7. Altered cellular mRNA levels in human cytomegalovirus-infected fibroblasts: Viral block to the accumulation of antiviral mRNAs
8. The herpes simplex virus US11 protein effectively compensates for the γ1(34.5) gene if present before activation of protein kinase R by precluding its phosphorylation and that of the alpha subunit of eukaryotic translation initiation factor 2
9. The second-site mutation in the herpes simplex virus recombinants lacking the γ134.5 genes precludes shutoff of protein synthesis by blocking the phosphorylation of eIF-2α
10. DNA microarrays of the complex human cytomegalovirus genome: Profiling kinetic class with drug sensitivity of viral gene expression
11. Rescue of vaccinia virus lacking the E3L gene by mutants of E3L
12. - mutants of herpes simplex virus 1
13. In vitro activation of the interferoninduced, double-stranded RNA-dependent protein kinase PKR by RNA from the 3′ untranslated regions of human α-tropomyosin
14. Translational control of cytomegalovirus gene expression is mediated by upstream AUG codons
15. - herpes simplex virus 1: Failure of activated RNA-dependent protein kinase to shut off protein synthesis is associated with a deletion in the domain of the a47 gene
16. - protein of herpes simplex virus 1 complexes with protein phosphatase la to dephosphorylate the a subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase
17. Regulation of mRNA translation and cellular signaling by hepatitis C virus nonstructural protein NS5A
18. Translational control in poxvirus-infected cells
19. Human cytomegalovirus infection of Caco-2 cells occurs at the basolateral membrane and is differentiation state dependent
20. The 58,000-dalton cellular inhibitor of the interferon-induced double-stranded RNA-activated protein kinase (PKR) is a member of the tetratricopeptide repeat family of proteins
21. Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene
22. Cytomegaloviruses and their replication
23. A herpes simplex virus type 1 γ34.5 second-site suppressor mutant that exhibits enhanced growth in cultured glioblastoma cells is severely attenuated in animals
24. Herpes simplex virus triggers and then disarms a host antiviral response
25. A herpesvirus ribosome-associated, RNA-binding protein confers a growth advantage upon mutants deficient in a GADD34-related function
26. Viral translational strategies and host defense mechanisms
27. Inhibition of PKR activation by the proline-rich RNA binding domain of the herpes simplex virus type 1 Us11 protein
28. Paradoxical interactions between human delta hepatitis agent RNA and the cellular protein kinase PKR
29. Adenovirus inhibition of cellular protein synthesis and preferential translation of viral mRNAs
30. Reovirus translational control
31. Role of the vaccinia virus E3L and K3L gene products in rescue of VSV and EMCV from the effects of IFN-a
32. Complementation of deletion of the vaccinia virus E3L gene by the Escherichia coli RNase III gene
33. Modified acid guanidinium thiocyanate-phenol-chloroform RNA extraction method which greatly reduces DNA contamination
34. Global modulation of cellular transcription by human cytomegalovirus is initiated by viral glycoprotein B
35. Synthesis of proteins and glycoproteins in cells infected with human cytomegalovirus
36. Translational reprogramming during influenza virus infection
37. Human cytomegalovirus stimulates host cell RNA synthesis
38. NYVAC: A highly attenuated strain of vaccinia virus
39. Expanded CUG repeat RNAs form hairpins that activate the double-stranded RNA-dependent protein kinase PKR
40. Ribosomal RNA cleavage, nuclease activation and 2-5A(ppp(A2′p)nA) in interferon-treated cells
41. Cellular gene expression altered by human cytomegalovirus: Global monitoring with oligonucleotide arrays
42. Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: Induction of interferon-responsive RNAs