Antibodies to 70 kD and 90 kD heat shock proteins are associated with graft-versus-host disease in peripheral blood stem cell transplant recipients

Clinical and Experimental Immunology

Volumn 127, Issue 3, 2002, Pages 553-559

  Goral, J ^a   Shenoy, S ^b   Mohanakumar, T ^b   Clancy Jr , J ^a  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

GVHD; hsp70; hsp90; PBSC transplantation

Indexed keywords

ANTIBODY; GRANULOCYTE COLONY STIMULATING FACTOR; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HLA ANTIGEN; IMMUNOGLOBULIN M;

ALLOGRAFT; ANTIBODY BLOOD LEVEL; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GRAFT REJECTION; GRAFT VERSUS HOST REACTION; HUMAN; HUMAN CELL; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; PERIPHERAL BLOOD STEM CELL; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PROGNOSIS; RISK FACTOR; STEM CELL TRANSPLANTATION;

ADULT; AGED; AUTOANTIBODIES; CHAPERONIN 60; FEMALE; GRAFT VS HOST DISEASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HSP70 HEAT-SHOCK PROTEINS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOGLOBULIN ISOTYPES; MALE; MIDDLE AGED;

EID: 0036239674     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2002.01770.x     Document Type: Article

References (49)

1. The application of BMT to the treatment of genetic diseases
2. The immunopathology of acute graft-versus-host-disease
3. Genetics of graft-versus-host disease, I. A locus on chromosome 1 influences development of acute graft-versus-host disease in major histocompatibility complex mismatched murine model
4. Imunogenetics of human minor histocompatibility antigens: Their polymorphism and immunodominance
5. Genetic polymorphism of human interleukin-1α
6. Allelic polymorphism in IL-1β and IL-1 receptor antagonist (IL-1Ra) genes in inflammatory bowel disease
7. Investigation of an interleukin-4 promoter polymorphism for associations with asthma and atopy
8. An investigation of polymorphism in the interleukin-10 gene promoter
9. Expression of 70-kDa heat-shock protein during acute graft-versus-host disease
10. Antibodies specific for the 70-kDa heat-shock protein parallel the development of acute graft-versus-host disease in (DA×LEW) F1 rats
11. Reduced levels of hsp70 result in a therapeutic effect of 15-deoxyspergualin on acute graft-versus-host disease in (DA×LEW) F1 rats
12. Protein folding in the cell
13. Response of mammalian cells to metabolic stress: Changes in cell physiology and structure/function of stress proteins
14. Danger signals: SOS to the immune system
15. Immune response against heat shock proteins in infectious diseases
16. Stress proteins are immune targets in leprosy and tuberculosis
17. Human T-cell clones to the 70-kilodalton heat shock protein of Mycobacterium leprae define mycobacterium-specific epitopes rather than shared epitopes
18. Identification of a heat shock-like antigen in P. falciparum, related to the heat shock protein 90 family
19. Infection, autoimmunity and autoimmune disease
20. Anti-heat shock protein 70 kDa and 90 kDa antibodies in serum of patients with rheumatoid arthritis
21. Stress proteins in colorectal mucosa. Enhanced expression in ulcerative colitis
22. Circulating antibodies to heat-shock protein 60 in Crohn's disease and ulcerative colitis
23. Experimental and clinical gnotobiotics: Influence of the microflora on graft-versus-host disease after allogeneic bone marrow transplantation
24. Influence of intestinal bacterial decontamination using metronidazole and ciprofloxacin or ciprofloxacin alone on the development of acute graft-versus-host disease after marrow transplantation in patients with hematologic malignances: Final results of long-term follow-up of an open-label prospective randomized trial
25. Heat shock protein reactivity of lymphocytes isolated from heterotopic rat cardiac allografts
26. Increased expression of HDJ-2 (heat shock protein 40) and heat shock protein 70 in biopsy specimens of transplanted human lungs
27. Induction of heat shock protein in cardiac allograft rejection - A cyclosporin-suppressible response
28. HLA-derived peptides which inhibit T cell function bind to members of the heat-shock protein 70 family
29. The HSC73 molecular chaperone: Involvement in MHC class II antigen presentation
30. Immunotherapy of tumors with autologous tumor-derived heat shock protein preparations
31. Co-segregation of tumor immunogenicity with expression of inducible but not constitutive hsp70 in rat colon carcinomas
32. + T cells react to B cell lines expressing heat shock protein 70
33. Interaction of the immunosuppressant deoxyspergualin with a member of the hsp70 family of heat shock proteins
34. Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-A matched sibling donors
35. Chronic graft-versus-host syndrome in man. A long-term clinicopathologic study of 20 Seattle patients
36. Specific antibodies against the stress-inducible 72-kDa protein, a member of the heat-shock protein hsp70, in healthy human subject
37. HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine
38. Prevention of graft versus host disease by inactivation of host antigen-presenting cells
39. T cell-independent rescue of B lymphocytes from peripheral immune tolerance
40. Induction and therapy of autoimmune diabetes in the non-obese diabetic (NOD/It) mouse by 65-kDa heat shock protein
41. The humoral immune system in inflammatory bowel disease. II. Immuoglobulin levels
42. Alterations in serum immunoglobulin G subclasses in patients with ulcerative colitis and Crohn's disease
43. Deoxyspergualin inhibits kappa light chain expression in 70Z/3 pre-B cells by blocking lipopolysaccharide-induced NF-kappa B activation
44. The I kappa B kinase (IKK) and NF-kappa B: Key elements of proinflammatory signaling
45. Functional diversity of helper T lymphocytes
46. Human interleukin 10 induces naïve surface immunoglobulin D+ (sIgD+) B cells to secrete IgG1 and IgG3
47. Expression of cytokine genes (TNFα, TGFβ and IFNγ) in acute lethal GVHD