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Volumn 65, Issue 3, 1997, Pages 1061-1070

Human T-cell clones to the 70-kilodalton heat shock protein of Mycobacterium leprae define mycobacterium-specific epitopes rather than shared epitopes

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; HEAT SHOCK PROTEIN 70; HLA DR ANTIGEN;

EID: 0031026310     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.3.1061-1070.1997     Document Type: Article
Times cited : (20)

References (53)
  • 1
    • 0025253693 scopus 로고
    • T cell reactivity to the purified mycobacterial antigens P65 and P70 in leprosy patients and their household contacts
    • Adams, E., R. J. Garsia, L. Helqvlst, P. Holt, and A. Basten. 1990. T cell reactivity to the purified mycobacterial antigens P65 and P70 in leprosy patients and their household contacts. Clin. Exp. Immunol. 80:206-212.
    • (1990) Clin. Exp. Immunol. , vol.80 , pp. 206-212
    • Adams, E.1    Garsia, R.J.2    Helqvlst, L.3    Holt, P.4    Basten, A.5
  • 2
    • 0027146621 scopus 로고
    • Identification of T cell epitopes in the Mycobacterium leprat heat shock protein 70 Kda antigen
    • Adams, E., W. J. Britton, A. Morgan, A. Goodsall, and A. Basten. 1993. Identification of T cell epitopes in the Mycobacterium leprat heat shock protein 70 Kda antigen. Clin. Exp. Immunol. 94:500-506.
    • (1993) Clin. Exp. Immunol. , vol.94 , pp. 500-506
    • Adams, E.1    Britton, W.J.2    Morgan, A.3    Goodsall, A.4    Basten, A.5
  • 3
    • 0028200809 scopus 로고
    • Individuals from different populations identify multiple and diverse T-cell determinants on mycobacterial Hsp70
    • Adams, E.. A. Morgan, A. Basten, S. Sergeantson, and W. J. Britton. 1994. Individuals from different populations identify multiple and diverse T-cell determinants on mycobacterial Hsp70. Scand. J. Immunol. 39:588-596.
    • (1994) Scand. J. Immunol. , vol.39 , pp. 588-596
    • Adams, E.1    Morgan, A.2    Basten, A.3    Sergeantson, S.4    Britton, W.J.5
  • 4
    • 0028900289 scopus 로고
    • Activation of T cells recognizing self 60-kD heat shock protein can protect against experimental arthritis
    • Anderton, S. M., R. van der Zee, B. Prakken, A. Noordzij, and W. van Eden. 1995. Activation of T cells recognizing self 60-kD heat shock protein can protect against experimental arthritis. J. Exp, Med. 181:943-952.
    • (1995) J. Exp, Med. , vol.181 , pp. 943-952
    • Anderton, S.M.1    Van der Zee, R.2    Prakken, B.3    Noordzij, A.4    Van Eden, W.5
  • 6
    • 1842336174 scopus 로고    scopus 로고
    • Unpublished observation
    • 5a.Baumgart, K. W. Unpublished observation.
    • Baumgart, K.W.1
  • 7
    • 0026464517 scopus 로고
    • Antibodies and reactive T cells against the malaria heat-shock protein Pf72/Hsp70-1 and derived peptides in individuals continuously exposed to Plasmodium falciparum
    • Behr, C., J.-L. Sarthou, C. Regier, J.-K. Trape, M. H. Q. Dat, J.-C. Michel, G. A. Dteye, J.-M. Claverle, P. Druihle, and P. Dubois, 1992. Antibodies and reactive T cells against the malaria heat-shock protein Pf72/Hsp70-1 and derived peptides in individuals continuously exposed to Plasmodium falciparum. J. Immunol. 149:3321-3330.
    • (1992) J. Immunol. , vol.149 , pp. 3321-3330
    • Behr, C.1    Sarthou, J.-L.2    Regier, C.3    Trape, J.-K.4    Dat, M.H.Q.5    Michel, J.-C.6    Dteye, G.A.7    Claverle, J.-M.8    Druihle, P.9    Dubois, P.10
  • 8
    • 0024324596 scopus 로고
    • Characterization of native and recombinant 75 kilodalton immunogens from Chlamydia trachomatis serovar L2
    • Birkelund, S., A. G. Lundenmose, and G. Christiansen. 1989. Characterization of native and recombinant 75 kilodalton immunogens from Chlamydia trachomatis serovar L2. Infect. Immun. 57:2683-2690.
    • (1989) Infect. Immun. , vol.57 , pp. 2683-2690
    • Birkelund, S.1    Lundenmose, A.G.2    Christiansen, G.3
  • 9
    • 0027223225 scopus 로고
    • Spinal fluid lymphocytes from a subgroup of multiple sclerosis patients respond to mycobacterial antigens
    • Birnbaum, G., L. Kotilinek, and L. Albrecht. 1993. Spinal fluid lymphocytes from a subgroup of multiple sclerosis patients respond to mycobacterial antigens. Ann. Neurol. 34:18-24.
    • (1993) Ann. Neurol. , vol.34 , pp. 18-24
    • Birnbaum, G.1    Kotilinek, L.2    Albrecht, L.3
  • 10
    • 0022243329 scopus 로고
    • Mycobacterium leprae antigens involved in human immune responses 1, Identification of four antigens by monoclonal antibodies
    • Britton, W. J., L. Helqvist, A. Basten, and R. L. Raison. 1985. Mycobacterium leprae antigens involved in human immune responses 1, Identification of four antigens by monoclonal antibodies. J. Immunol. 135:4171-4177.
    • (1985) J. Immunol. , vol.135 , pp. 4171-4177
    • Britton, W.J.1    Helqvist, L.2    Basten, A.3    Raison, R.L.4
  • 11
    • 0022483526 scopus 로고
    • Immunoreactivity of a 70 kDa protein purified from Mycobacterium bovis Bacillus Calmette-Guerin by monoclonal antibody affinity chromatography
    • Britton, W. J., L. Helqvist, A. Basten, and A. S. Inglis. 1986. Immunoreactivity of a 70 kDa protein purified from Mycobacterium bovis Bacillus Calmette-Guerin by monoclonal antibody affinity chromatography. J. Exp. Med. 164:695-708.
    • (1986) J. Exp. Med. , vol.164 , pp. 695-708
    • Britton, W.J.1    Helqvist, L.2    Basten, A.3    Inglis, A.S.4
  • 12
    • 1842298049 scopus 로고
    • Protective immunity against mycobacterial infection, investigating cloned antigen
    • J. McFadden (ed.). Academic Press Ltd., London, United Kingdom
    • Colston, M. J. 1990. Protective immunity against mycobacterial infection, investigating cloned antigen, p. 69-78. In J. McFadden (ed.). Molecular biology of the mycobacteria. Academic Press Ltd., London, United Kingdom.
    • (1990) Molecular Biology of the Mycobacteria , pp. 69-78
    • Colston, M.J.1
  • 13
    • 0026553479 scopus 로고
    • The variable C-terminal region of the Mycobacterium leprae 70-kilodalton heat shock protein is the target for humoral immune responses
    • Davenport, M. P., K. K. McKenzie, A. Basten, and W. J. Britton. 1992. The variable C-terminal region of the Mycobacterium leprae 70-kilodalton heat shock protein is the target for humoral immune responses. Infect. Immun. 60:1170-1177.
    • (1992) Infect. Immun. , vol.60 , pp. 1170-1177
    • Davenport, M.P.1    McKenzie, K.K.2    Basten, A.3    Britton, W.J.4
  • 15
    • 0023649886 scopus 로고
    • Structure and expression of a human gene coding for a 71 kD heat shock "cognate" protein
    • Dworniczak, B., and M. Mirault. 1987. Structure and expression of a human gene coding for a 71 kD heat shock "cognate" protein. Nucleic Acids Res. 15:5181-5197.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 5181-5197
    • Dworniczak, B.1    Mirault, M.2
  • 16
    • 0027181575 scopus 로고
    • Molecular cloning of a novel human hsp70 from a B-cell line and its assignment to chromosome 5
    • Fathallah, D. M., D. Cherif, K. Dellagi, and M. A. Arnout. 1993. Molecular cloning of a novel human hsp70 from a B-cell line and its assignment to chromosome 5. J. Immunol. 151:810-813.
    • (1993) J. Immunol. , vol.151 , pp. 810-813
    • Fathallah, D.M.1    Cherif, D.2    Dellagi, K.3    Arnout, M.A.4
  • 17
    • 0028926788 scopus 로고
    • Experimental autoimmune encephalomyelitis: Qualitative and semiqualitative differences in heat shock protein 60 expression
    • Gao, Y. L., C. F. Broscan, and C. S. Raines. 1995. Experimental autoimmune encephalomyelitis: qualitative and semiqualitative differences in heat shock protein 60 expression. J. Immunol. 154:3548-3556.
    • (1995) J. Immunol. , vol.154 , pp. 3548-3556
    • Gao, Y.L.1    Broscan, C.F.2    Raines, C.S.3
  • 18
    • 0025303766 scopus 로고
    • Recognition of a mycobacteria-specific epitope in the 65-kD heat shock protein by synovial fluid-derived T cell clones
    • Gaston, J. S. H., P. F. Life, P. J. Jenner, M. J. Colston, and P. A. Bacon. 1990. Recognition of a mycobacteria-specific epitope in the 65-kD heat shock protein by synovial fluid-derived T cell clones. J. Exp. Med. 171:831-841.
    • (1990) J. Exp. Med. , vol.171 , pp. 831-841
    • Gaston, J.S.H.1    Life, P.F.2    Jenner, P.J.3    Colston, M.J.4    Bacon, P.A.5
  • 19
    • 0029078670 scopus 로고
    • Marked conservation of complementarity-determining region 3 of the beta-chain of TcRs recognizing a mycobacterial heat shock protein 60-derived peptide with strong sequence similarity to human heat shock protein 60
    • Goodall, J. C., J. Henwood, P. A. Bacon, J. S. H. Gaston. 1995. Marked conservation of complementarity-determining region 3 of the beta-chain of TcRs recognizing a mycobacterial heat shock protein 60-derived peptide with strong sequence similarity to human heat shock protein 60. J. Immunol. 155:2329-2338.
    • (1995) J. Immunol. , vol.155 , pp. 2329-2338
    • Goodall, J.C.1    Henwood, J.2    Bacon, P.A.3    Gaston, J.S.H.4
  • 21
    • 0027155109 scopus 로고
    • Restricted T-cell receptor expression by human T-cell clones specific for mycobacterial 65 kDa heat shock protein: Selective in vivo expansion of T-cells bearing defined receptors
    • Henwood, J., J. Love ridge, J. I. Bell, and J. S. H. Gaston. 1993. Restricted T-cell receptor expression by human T-cell clones specific for mycobacterial 65 kDa heat shock protein: selective in vivo expansion of T-cells bearing defined receptors. Eur. J. Immunol. 23:1256-1265.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1256-1265
    • Henwood, J.1    Love Ridge, J.2    Bell, J.I.3    Gaston, J.S.H.4
  • 22
    • 0000478940 scopus 로고
    • General method for the rapid solid phase synthesis of a large number of peptides: Specificity of antigen-antibody interaction at the level of individual amino acids
    • Houghten, R. A. 1984. General method for the rapid solid phase synthesis of a large number of peptides: specificity of antigen-antibody interaction at the level of individual amino acids. Proc. Natl. Acad. Sci. USA 82:5131-5135.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 5131-5135
    • Houghten, R.A.1
  • 23
    • 0000097632 scopus 로고
    • Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70
    • Hunt, C., and R. I. Morimoto. 1985. Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70. Proc. Natl. Acad. Sci. USA 82:6455-6459.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 6455-6459
    • Hunt, C.1    Morimoto, R.I.2
  • 25
    • 0020078842 scopus 로고
    • Antigen-specific human T lymphocyte clones: Induction, antigen specificity, and MHC restriction of influenza virus-immune clones
    • Lamb, J. R., D. D. Eckels, P. Lake, A. H. Johnson, R. J. Hartzman, and J. N. Woody. 1982. Antigen-specific human T lymphocyte clones: induction, antigen specificity, and MHC restriction of influenza virus-immune clones. J. Immunol. 128:233-238.
    • (1982) J. Immunol. , vol.128 , pp. 233-238
    • Lamb, J.R.1    Eckels, D.D.2    Lake, P.3    Johnson, A.H.4    Hartzman, R.J.5    Woody, J.N.6
  • 27
    • 0025363926 scopus 로고
    • The human heat-shock protein family: Expression of a novel heat-inducible HSP70 (HSP70B') and isolation of its cDNA and genomic DNA
    • Leung, T. K. C., M. Y. Rajendran, C. Monfries, C. Halls, and L. Lim. 1990. The human heat-shock protein family: expression of a novel heat-inducible HSP70 (HSP70B') and isolation of its cDNA and genomic DNA. Biochem. J. 267:125-132.
    • (1990) Biochem. J. , vol.267 , pp. 125-132
    • Leung, T.K.C.1    Rajendran, M.Y.2    Monfries, C.3    Halls, C.4    Lim, L.5
  • 28
    • 0025864103 scopus 로고
    • Efficient cDNA expression vectors for stable and transient expression of HLA-DR in transfected fibroblast and lymphoid cells
    • Long, E. O., S. Rosen-Bronson, D. R. Karp, M. Malnati, R. P. Sekaly, and D. Jaraquemada. 1991. Efficient cDNA expression vectors for stable and transient expression of HLA-DR in transfected fibroblast and lymphoid cells. Hum. Immunol. 31:229-235.
    • (1991) Hum. Immunol. , vol.31 , pp. 229-235
    • Long, E.O.1    Rosen-Bronson, S.2    Karp, D.R.3    Malnati, M.4    Sekaly, R.P.5    Jaraquemada, D.6
  • 31
    • 0025119456 scopus 로고
    • Multipin peptide synthesis strategy for T cell determinant analysis
    • Maeji, J. N., A. B. Bray, and H. M. Geysen. 1990. Multipin peptide synthesis strategy for T cell determinant analysis. J. Immunol. Methods 134:23-33.
    • (1990) J. Immunol. Methods , vol.134 , pp. 23-33
    • Maeji, J.N.1    Bray, A.B.2    Geysen, H.M.3
  • 32
    • 0025942341 scopus 로고
    • Sequence and immunogenicity of the 70-kDa heat shock protein of Mycobacterium leprae
    • McKenzie, K. R., E. Adams, W. J. Britton, R. J. Garsia, and A. Basten. 1991. Sequence and immunogenicity of the 70-kDa heat shock protein of Mycobacterium leprae. J. Immunol. 1-47:312-319.
    • (1991) J. Immunol. , vol.1-47 , pp. 312-319
    • McKenzie, K.R.1    Adams, E.2    Britton, W.J.3    Garsia, R.J.4    Basten, A.5
  • 33
    • 0025095784 scopus 로고
    • Structure and expression of the three MHC-linked HSP70 genes
    • Milner, C. M., and R. D. Campbell. 1990. Structure and expression of the three MHC-linked HSP70 genes. Immunogenetics 32:242-251.
    • (1990) Immunogenetics , vol.32 , pp. 242-251
    • Milner, C.M.1    Campbell, R.D.2
  • 34
    • 0024424920 scopus 로고
    • T lymphocytes from healthy individuals with specificity to self-epitopes shared by the mycobacterial and human 65-kilodalton heat shock protein
    • Munk, M. E., B. Schoel, S. Modrow, R. W. Karr, R. A. Young, and S. H. E. Kaufmann. 1984. T lymphocytes from healthy individuals with specificity to self-epitopes shared by the mycobacterial and human 65-kilodalton heat shock protein. J. Immunol. 143:2844-2840.
    • (1984) J. Immunol. , vol.143 , pp. 2844-12840
    • Munk, M.E.1    Schoel, B.2    Modrow, S.3    Karr, R.W.4    Young, R.A.5    Kaufmann, S.H.E.6
  • 35
    • 0027960195 scopus 로고
    • Mapping of multiple HLA class II-restricted T-cell epitopes of the mycobacterial 70-kilodalton heat shock protein
    • Oftung, F., A. Geluk, K. Lundin, R. H. Meleon, J. E. R. Thole, A. S. Mustafa, and T. H. M. Ottenhoff. 1994. Mapping of multiple HLA class II-restricted T-cell epitopes of the mycobacterial 70-kilodalton heat shock protein. Infect. Immun. 62:5411-5418.
    • (1994) Infect. Immun. , vol.62 , pp. 5411-5418
    • Oftung, F.1    Geluk, A.2    Lundin, K.3    Meleon, R.H.4    Thole, J.E.R.5    Mustafa, A.S.6    Ottenhoff, T.H.M.7
  • 37
    • 0025363054 scopus 로고
    • Specific killing of cytotoxic T cells and antigen-presenting cells by CD4 cytotoxic T cell clones: A novel potentially immunoregulatory T-Tcell interaction in man
    • Ottenhoff, T. H. M., and T. Mutis. 1990. Specific killing of cytotoxic T cells and antigen-presenting cells by CD4 cytotoxic T cell clones: a novel potentially immunoregulatory T-Tcell interaction in man. J. Exp. Med. 171:2011-2024.
    • (1990) J. Exp. Med. , vol.171 , pp. 2011-2024
    • Ottenhoff, T.H.M.1    Mutis, T.2
  • 39
    • 0025720118 scopus 로고
    • Characterization of the functional properties of the 70 kDa protein of Mycobacterium leprae
    • Peake, P., A. Basten, and W. J. Britton. 1991. Characterization of the functional properties of the 70 kDa protein of Mycobacterium leprae. J. Biol. Chem. 266:20828-20833.
    • (1991) J. Biol. Chem. , vol.266 , pp. 20828-20833
    • Peake, P.1    Basten, A.2    Britton, W.J.3
  • 40
    • 0019413925 scopus 로고
    • Spontaneous release of a factor with properties of T cell growth factor from a continuous line of primate tumour cells
    • Rabin, H., R. F. Hopkins III, F. W. Ruscetti, R. H. Neubauer, R. L. Brown, and T. G. Kawakami. 1981. Spontaneous release of a factor with properties of T cell growth factor from a continuous line of primate tumour cells. J. Immunol. 127:1852-1856.
    • (1981) J. Immunol. , vol.127 , pp. 1852-1856
    • Rabin, H.1    Hopkins III, R.F.2    Ruscetti, F.W.3    Neubauer, R.H.4    Brown, R.L.5    Kawakami, T.G.6
  • 41
    • 0024244787 scopus 로고
    • Specificity of proliferate response of human CD8 clones to mycobacterial antigens
    • Rees, A., A. Scoging, A. Mehlert, D. B. Young, and J. Ivanyi. 1988. Specificity of proliferate response of human CD8 clones to mycobacterial antigens. Eur. J. Immunol. 18:1881-1887.
    • (1988) Eur. J. Immunol. , vol.18 , pp. 1881-1887
    • Rees, A.1    Scoging, A.2    Mehlert, A.3    Young, D.B.4    Ivanyi, J.5
  • 42
    • 1842298621 scopus 로고    scopus 로고
    • Unpublished observation
    • 40a.Roche, P. W. Unpublished observation.
    • Roche, P.W.1
  • 43
    • 0024517766 scopus 로고
    • Human major histocompatibility complex contains genes for the major heat shock protein Hsp70
    • Sargent, C. A., I. Dunham, J. Trowsdale, and R. D. Campbell. 1989. Human major histocompatibility complex contains genes for the major heat shock protein Hsp70. Proc. Natl. Acad. Sci. USA 86:1968-1972.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 1968-1972
    • Sargent, C.A.1    Dunham, I.2    Trowsdale, J.3    Campbell, R.D.4
  • 44
    • 0024310144 scopus 로고
    • Heat shock protein cognate 70 is a prominent immunogen in brugian filariasis
    • Selkirk, M. E., D. A. Denham, F. Partono, and R. M. Maizels. 1989 Heat shock protein cognate 70 is a prominent immunogen in brugian filariasis. J. Immunol. 143:209-308.
    • (1989) J. Immunol. , vol.143 , pp. 209-308
    • Selkirk, M.E.1    Denham, D.A.2    Partono, F.3    Maizels, R.M.4
  • 45
  • 46
    • 1842373738 scopus 로고
    • A single mycobacterial heat shock protein (Hsp65) expressed by a transgenic antigen-presenting cell vaccinates against tuberculosis
    • Silva, C. L., and D. B. Lowrie. 1994. A single mycobacterial heat shock protein (Hsp65) expressed by a transgenic antigen-presenting cell vaccinates against tuberculosis. Immunology 82:2400-2407.
    • (1994) Immunology , vol.82 , pp. 2400-2407
    • Silva, C.L.1    Lowrie, D.B.2
  • 48
    • 0029071796 scopus 로고
    • Increased frequency of gamma-delta T cells in cerebrospinal fluid and peripheral blood of patients with multiple sclerosis: Reactivity, cytotoxicity and T cell receptor V gene rearrangements
    • Stinnisen, P., C. Vandevyer, R. Medaer, L. Vandegaar, J. Nies, L. Tuyls, A. D. Hafler, J. Raus, and J. Zhang. 1995. Increased frequency of gamma-delta T cells in cerebrospinal fluid and peripheral blood of patients with multiple sclerosis: reactivity, cytotoxicity and T cell receptor V gene rearrangements. J. Immunol. 154:4883-4894.
    • (1995) J. Immunol. , vol.154 , pp. 4883-4894
    • Stinnisen, P.1    Vandevyer, C.2    Medaer, R.3    Vandegaar, L.4    Nies, J.5    Tuyls, L.6    Hafler, A.D.7    Raus, J.8    Zhang, J.9
  • 50
    • 0027260585 scopus 로고
    • Heat shock protein 70-associated peptides elicit specific cancer immunity
    • Udono, H., and P. K. Srivastava. 1993. Heat shock protein 70-associated peptides elicit specific cancer immunity. J. Exp. Med. 178:1391-1396.
    • (1993) J. Exp. Med. , vol.178 , pp. 1391-1396
    • Udono, H.1    Srivastava, P.K.2
  • 51
    • 0025921494 scopus 로고
    • Heat shock proteins as immunogenic bacterial antigens with the potential to induce and regulate autoimmune arthritis
    • van Eden, W. 1991. Heat shock proteins as immunogenic bacterial antigens with the potential to induce and regulate autoimmune arthritis. Immunol. Rev. 121:5-28.
    • (1991) Immunol. Rev. , vol.121 , pp. 5-28
    • Van Eden, W.1
  • 52
    • 0025921501 scopus 로고
    • Do stress proteins play a role in arthritis and autoimmunity? Immunol
    • Winfield, J., and W. Jarjou. 1991. Do stress proteins play a role in arthritis and autoimmunity? Immunol. Rev. 121:193-120.
    • (1991) Rev. , vol.121 , pp. 193-1120
    • Winfield, J.1    Jarjou, W.2
  • 53
    • 0025247797 scopus 로고
    • Stress proteins and immunity
    • Young, R. A. 1990. Stress proteins and immunity. Annu. Rev. Immunol. 8:401-420.
    • (1990) Annu. Rev. Immunol. , vol.8 , pp. 401-420
    • Young, R.A.1


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