Prediction of rodent nongenotoxic carcinogenesis: Evaluation to biochemical and tissue changes in rodents following exposure to nine nongenotoxic NTP carcinogens

Environmental Health Perspectives

Volumn 110, Issue 4, 2002, Pages 363-375

  Elcombe, Clifford R ^a,c   Odum, Jenny ^a   Foster, John R ^a   Stone, Susan ^a   Hasmall, Susan ^a   Soames, Anthony R ^a   Kimber, Ian ^a   Ashby, John ^a,b  

^a JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Kidney; Liver; Nongenotoxic carcinogenesis; Thyroid

Indexed keywords

1,4 DICHLOROBENZENE; 2 IMIDAZOLIDINETHIONE; BIOCHEMICAL MARKER; CARCINOGEN; CHLORENDIC ACID; CINNAMYL ANTHRANILATE; CYTOCHROME P450; HYALIN; LIMONENE; LIOTHYRONINE; LIVER ENZYME; MONURON; PALMITOYL COENZYME A; PEROXISOME PROLIFERATOR; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; THIOUREA; THYROTROPIN; THYROXINE;

ANIMAL TISSUE; ARTICLE; BASOPHILIA; BIOASSAY; BIOCHEMISTRY; CELL LABELING; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; CORRELATION FUNCTION; GENOTOXICITY; HISTOPATHOLOGY; HYPERTROPHY; KIDNEY PARENCHYMA; KIDNEY TUBULE; LABELING INDEX; LIOTHYRONINE BLOOD LEVEL; LIVER CARCINOGENESIS; LIVER WEIGHT; MICROMORPHOLOGY; MOUSE; MOUSE STRAIN; NONHUMAN; PREDICTION; PRIORITY JOURNAL; RAT; RAT STRAIN; RODENT; SENSITIVITY AND SPECIFICITY; THYROID FUNCTION; THYROID GLAND; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL; TOXICITY TESTING; UNITED STATES;

ANIMALIA; RODENTIA;

EID: 0036230059     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.02110363     Document Type: Article

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