Long-term chemical carcinogenesis bioassays predict human cancer hazards. Issues, controversies, and uncertainties

Annals of the New York Academy of Sciences

Volumn 895, Issue , 1999, Pages 56-79

  Huff, James ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; CHEMICAL AGENT; COAL TAR; TRICHLOROETHYLENE;

ANALYTICAL ERROR; BIOASSAY; CANCER LOCALIZATION; CANCER RISK; CARCINOGEN TESTING; CHEMICAL CARCINOGENESIS; CONFERENCE PAPER; DIET; ENVIRONMENTAL EXPOSURE; EXPERIMENTAL ANIMAL; HUMAN; LIFESTYLE; LIVER TUMOR; METHODOLOGY; NONHUMAN; OCCUPATIONAL EXPOSURE; PREDICTION;

ANIMALIA; ORYCTOLAGUS CUNICULUS; RODENTIA;

EID: 0033403543     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb08077.x     Document Type: Conference Paper

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156. 156. Farber, E. 1995. Cell proliferation as a major risk factor for cancer: a concept of doubtful validity. Cancer Res. 55(17): 3759-3762.
157. 157. Farber, E. 1996. Cell proliferation is not a major risk factor for cancer. Mod. Pathol. 9(6): 606.
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163. 163. Melnick, R.L., G.A. Boorman, J.K. Haseman, R.J. Montali & J.E. Huff. 1984. Urolithiasis and bladder carcinogenicity of melamine in rodents. Toxicol. Appl. Pharmacol. 72(2): 292-303.
164. 164. Perera, F., T. Brennan & J.R. Fouts. 1989. Comment on the significance of positive carcinogenicity studies using gavage as the route of exposure. Environ. Health Perspect. 79:315-321.
165. 165. Haseman, J.K. & J.E. Huff. 1987. Species correlation in long-term carcinogenicity studies. Cancer Lett. 37(2): 125-132. (Published erratum appears in Cancer Lett. 38(3): 365, 1988.)
166. 166. Haseman, J.K. 1999. Using the NTP database to assess the value of rodent carcinogenicity studies for determining human cancer risk. Drug Metab. Rev. In press.