Comparison of the hepatic and renal effects of 1,4-dichlorobenzene in the rat and mouse

Fundamental and Applied Toxicology

Volumn 39, Issue 1, 1997, Pages 67-75

  Lake, Brian G ^a   Cunninghame, Morag E ^a   Price, Roger J ^a  

^a BIBRA INTERNATIONAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DICHLOROBENZENE;

ANIMAL EXPERIMENT; ARTICLE; CELL DIVISION; CONTROLLED STUDY; KIDNEY TUMOR; LIVER TOXICITY; LIVER TUMOR; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; RAT; SPECIES DIFFERENCE; XENOBIOTIC METABOLISM;

ANIMALIA; ZEA MAYS;

EID: 26844487509     PISSN: 02720590     EISSN: None     Source Type: Journal    
DOI: 10.1006/faat.1997.2350     Document Type: Article

References (53)

1. Allis J. W., Simmons J. E., House D. E., Robinson B. L., Berman E. The differential hepatotoxicity and cytochrome P450 responses of Fischer-344 rats to the three isomers of dichlorobenzene. J. Biochem. Toxicol. 7:1992;257-264.
2. Ames B. N., Shigenaga M. K., Gold L. S. DNA lesions, inducible DNA repair, and cell division: Three key factors in mutagenesis and carcinogenesis. Environ. Health Perspect. 101:1993;35-44.
3. Andersen M. E., Mills J. J., Jirtle R. L., Greenlee W. F. Negative selection in hepatic tumor promotion in relation to cancer risk assessment. Toxicology. 102:1995;223-237.
4. Azouz W. M., Parke D. V., Williams R. T. Studies in detoxication. 62. The metabolism of halogenobenzenes:Orthopara. Biochem. J. 59:1955;410-415.
5. Barrass N. C., Price R. J., Lake B. G., Orton T. C. Comparison of the acute and chronic mitogenic effects of the peroxisome proliferators methylclofenapate and clofibric acid in rat liver. Carcinogenesis. 14:1993;1451-1456.
6. Bogaards J. J. P., van Ommen B., Wolf C. R., van Bladeren P. J. Human cytochrome P450 enzyme selectivities in the oxidation of chlorinated benzenes. Toxicol. Appl. Pharmacol. 132:1995;44-52.
7. 2U. Regul. Toxicol. Pharmacol. 18:1993;357-364.
8. 2U. Annu. Rev. Pharmacol. Toxicol. 30:1990;349-367.
9. Burke M. D., Thompson S., Elcombe C. R., Halpert J., Haaparanta T., Mayer R. T. Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: A series of substrates to distinguish between difference induced cytochromes P-450. Biochem. Pharmacol. 34:1985;3337-3345.
10. Butterworth B. E. Chemically induced cell proliferation as a predictive assay for potential carcinogenicity. Chemically Induced Cell Proliferation: Implications for Risk Assessment. 1991;Wiley-Liss, New York. p. 457-467.
11. 2U. Toxicol. Appl. Pharmacol. 99:1989;122-132.
12. Cohen S. M., Ellwein L. B. Genetic errors, cell proliferation and carcinogenesis. Cancer Res. 51:1991;6493-6505.
13. Cunningham M. L. Role of increased DNA replication in the carcinogenic risk of nonmutagenic chemical carcinogens. Mutat. Res. 365:1996;59-69.
14. Dietrich D. R., Swenberg J. A. Prenoeplastic lesions in rodent kidney induced spontaneously or by non-genotoxic agents: Predictive nature and comparison to lesions induced by genotoxic carcinogens. Mutat. Res. 248:1991a;239-260.
15. 2Ud. Cancer Res. 51:1991b;3512-3521.
16. 2U2U. Fundam. Appl. Toxicol. 16:1991c;749-762.
17. Eldridge S. R., Goldsworthy T. L., Popp J. A., Butterworth B. E. Mitogenic stimulation of hepatocellular proliferation in rodents following 1,4-dichlorobenzene administration. Carcinogenesis. 13:1992;409-415.
18. 3. Carcinogenesis. 11:1990;2245-2251.
19. Flamm W. G., Lehman-McKeeman L. D. The human relevance of the renal tumor-inducing potential ofd. Regul. Toxicol. Pharmacol. 13:1991;70-86.
20. Goldsworthy T. L., Conolly R. B., Fransson-Steen R. Apoptosis and cancer risk assessment. Mutat. Res. 365:1996;71-90.
21. Grasso P., Hinton R. H. Evidence for and possible mechanisms of non-genotoxic carcinogenesis in rodent liver. Mutat. Res. 248:1991;271-290.
22. Grasso P., Sharratt M., Cohen A. J. Role of persistent, non-genotoxic tissue damage in rodent cancer and relevance to humans. Annu. Rev. Pharmacol. Toxicol. 31:1991;253-287.
23. Haseman J. K., Clark A.-M. Carcinogenicity results for 114 laboratory animal studies used to assess the predictivity of fourin vitro. Environ. Mol. Mutagen. 16:1990;15-31.
24. 14. Xenobiotica. 10:1980;81-95.
25. Japenga A. C., Davies S., Price R. J., Lake B. G. Effect of treatment with pyrazine and some derivatives on cytochrome P450 and some enzyme activities in rat liver. Xenobiotica. 23:1993;169-179.
26. Jirtle R. L. Liver tumor promotion and breast cancer chemoprevention: common mechanisms. Cockburn A., Smith L. Nongenotoxic Carcinogenesis: Ernst Schering Research Foundation Workshop 10. 1994;157-171 Springer-Verlag, Berlin.
27. Klos C., Dekant W. Comparative metabolism of the renal carcinogen 1,4-dichlorobenzene in rat: Identification and quantitation of novel metabolites. Xenobiotica. 24:1994;965-976.
28. Lake B. G. Preparation and characterisation of microsomal fractions for studies of xenobiotic metabolism. Snell K., Mullock B. Biochemical Toxicology: A Practical Approach. 1987;183-215 IRL Press, Oxford.
29. Lake B. G. Mechanisms of hepatocarcinogenicity of peroxisome-proliferating drugs and chemicals. Annu. Rev. Pharmacol. Toxicol. 35:1995;483-507.
30. Lake B. G., Grasso P. Comparison of the hepatotoxicity of coumarin in the rat, mouse and Syrian hamster: A dose and time response study. Fundam. Appl. Toxicol. 34:1996;105-117.
31. Lake B. G., Beamand J. A., Wield P. T., Price R. J. Use of precision-cut liver slices to evaluate species differences in 2-acetylaminofluorene-induced unscheduled DNA synthesis. Toxicol. Appl. Pharmacol. 138:1996;231-241.
32. Loeser E., Litchfield M. H. Review of recent toxicology studies onp. Food Chem. Toxicol. 21:1983;825-832.
33. Loury D. J., Goldsworthy T. L., Butterworth B. E. The value of measuring cell replication as a predictive index of tissue-specific tumorigenic potential. Butterworth B. E., Slaga T. J. Nongenotoxic Mechanisms in Carcinogenesis. Banbury Report 25. 1987;119-136 Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
34. Lowry O. H., Rosebrough N. J., Farr A. L., Randall R. J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
35. Lubet R. A., Syi J-L., Nelson J. O., Nims R. W. Induction of hepatic cytochromePOP. Chem. Biol. Interact. 75:1990;325-339.
36. Melnick R. L., Huff J. Liver carcinogenesis is not a predicted outcome of chemically induced hepatocyte proliferation. Toxicol. Ind. Health. 9:1993;415-438.
37. Melnick R. L., Kohn M. C., Portier C. J. Implications for risk assessment of suggested nongenotoxic mechanisms of chemical carcinogenesis. Environ. Health Perspect. 104:1996;123-134.
38. Murray M., Reidy G. F. Selectivity of the inhibition of mammalian cytochromes P-450 by chemical agents. Pharmacol. Rev. 42:1990;85-101.
39. 1, U.S. Department of Health and Human Services, NTP, Research Triangle Park, North Carolina.
40. Nelson D. R., Koymans L., Kamataki T., Stegeman J. J., Feyereisen R., Waxman D. J., Waterman M. R., Gotoh O., Coon M. J., Estabrook R. W., Gunsalus I. C., Nebert D. W. P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics. 6:1996;1-42.
41. R. W. Nims, R. A. Lubet, 1996, The CYP2B subfamily, Cytochromes P450: Metabolic and Toxicological Aspects, C. Ioannides, 135, 160, CRC Press, Boca Raton, FL.
42. Omura T., Sato R. The carbon monoxide-binding pigment of liver microsomes. 1. Evidence for its hemoprotein nature. J. Biol. Chem. 239:1964;2370-2378.
43. Orton T. C., Doughty S. E., Kalinowski A. E., Lord P. G., Wadsworth P. F. Expression of growth factors and growth factor receptors in the liver of C57BL/10J mice following administration of phenobarbitone. Carcinogenesis. 17:1996;973-981.
44. 2U. Toxicol. Appl. Pharmacol. 101:1989;414-431.
45. Short B. G., Burnett V. L., Cox M. G., Bus J. S., Swenberg J. A. Site-specific renal cytotoxicity and cell proliferation in male rats exposed to petroleum hydrocarbons. Lab. Invest. 57:1987;564-577.
46. Steinmetz K. L., Bakke J. P., Hamilton C. M., Pardo K. C., Ramsey M., Mirsalis J. C. Evaluation of unscheduled DNA synthesis (UDS) and S-phase synthesis (SPS) following treatment withp. Toxicologist. 8:1988;160.
47. 2U. Toxicol. Appl. Pharmacol. 97:1989;35-46.
48. Umemura T., Saito M., Takagi A., Kurokawa Y. Isomer-specific acute toxicity and cell proliferation in livers of B6C3F1 mice exposed to dichlorobenzene. Toxicol. Appl. Pharmacol. 137:1996;268-274.
49. Umemura T., Tokumo K., Williams G. M. Cell proliferation induced in the kidneys and livers of rats and mice by short term exposure to the carcinogenp. Arch. Toxicol. 66:1992;503-507.
50. Valentovic M. A., Ball J. G., Anestis D., Madan E. Acute hepatic and renal toxicity of dichlorobenzene isomers in Fischer 344 rats. J. Appl. Toxicol. 13:1993;1-7.
51. Ward J. M., Shibata M.-A., Devor D. E. Emerging issues in mouse liver carcinogenesis. Toxicol. Pathol. 24:1996;129-137.
52. Weisburger J. H. Does the Delaney clause of the U.S. Food and Drug Laws prevent human cancers? Fundam. Appl. Toxicol. 22:1994;483-493.
53. Whysner J., Ross P. M., Williams G. M. Phenobarbital mechanistic data and risk assessment: Enzyme induction, enhanced cell proliferation, and tumor promotion. Pharmacol. Ther. 71:1996;153-191.