Comparison of the effects of cinnamyl anthranilate on hepatic peroxisome proliferation and cell replication in the rat and mouse

Fundamental and Applied Toxicology

Volumn 39, Issue 1, 1997, Pages 60-66

  Lake, Brian G ^a   Price, Roger J ^a   Cunninghame, Morag E ^a   Walters, David G ^a  

^a BIBRA INTERNATIONAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CINNAMYL ANTHRANILATE; PEROXISOME PROLIFERATOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIVISION; CONTROLLED STUDY; DNA SYNTHESIS; FEMALE; LIVER CARCINOGENESIS; LIVER CELL; LIVER TUMOR; MOUSE; NONHUMAN; RAT; SEX DIFFERENCE; SPECIES DIFFERENCE;

ANIMALIA;

EID: 26844560184     PISSN: 02720590     EISSN: None     Source Type: Journal    
DOI: 10.1006/faat.1997.2340     Document Type: Article

References (30)

1. Ashby J. An opinion on the significance of the 19 non-clastogenic gene-mutagens reported by Tennantet al. Mutagenesis. 3:1988;463-465.
2. Ashby J., Brady A., Elcombe C. R., Elliott B. M., Ishmael J., Odum J., Tugwood J. D., Kettle S., Purchase I. F. H. Mechanistically-based human hazard assessment of peroxisome proliferator-induced hepatocarcinogenesis. Hum. Exp. Toxicol. 13:1994;S1-S117.
3. Barrass N. C., Price R. J., Lake B. G., Orton T. C. Comparison of the acute and chronic mitogenic effects of the peroxisome proliferators methylclofenapate and clofibric acid in rat liver. Carcinogenesis. 14:1993;1451-1456.
4. Bentley P., Calder I., Elcombe C., Grasso P., Stringer D., Wiegand H.-J. Hepatic peroxisome proliferation in rodents and its significance for humans. Food Chem. Toxicol. 31:1993;857-907.
5. Caldwell J. Problems and opportunities in toxicity testing arising from species differences in xenobiotic metabolism. Toxicol. Lett. 64/65:1992;651-659.
6. 1. Food Chem. Toxicol. 23:1985;559-566.
7. Elcombe C. R. Species differences in carcinogenicity and peroxisome proliferation due to trichloroethylene : A biochemical human hazard assessment. Arch. Toxicol. 1985;6-17.
8. Gray T. J. B., Lake B. G., Beamand J. A., Foster J. R., Gangolli S. D. Peroxisome proliferation in primary cultures of rat hepatocytes. Toxicol. Appl. Pharmacol. 67:1983;15-25.
9. IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Some Food Additives, Feed Additives and Naturally Occurring Substances. 31:1983;133-139.
10. James N. H., Roberts R. A. Species differences in response to peroxisome proliferators correlatein vitro. Carcinogenesis. 17:1996;1623-1632.
11. Keyhanfar F., Caldwell J. Factors affecting the metabolism of cinnamyl anthranilate in the rat and mouse. Food Chem. Toxicol. 34:1996;241-249.
12. Lake B. G. Preparation and characterisation of microsomal fractions for studies of xenobiotic metabolism. Biochemical Toxicology: A Practical Approach. 1987;IRL Press, Oxford. p. 183-215.
13. Lake B. G. Role of oxidative stress and enhanced cell replication in the hepatocarcinogenicity of peroxisome proliferators. Gibson G., Lake B. Peroxisomes: Biology and Importance in Toxicology and Medicine. 1993;595-618 Taylor and Francis, London.
14. Lake B. G. Mechanisms of hepatocarcinogenicity of peroxisome-proliferating drugs and chemicals. Annu. Rev. Pharmacol. Toxicol. 35:1995;483-507.
15. Lake B. G., Lewis D. F. V. Structure-activity relationships for chemically induced peroxisome proliferation in mammalian liver. Gibson G., Lake B. Peroxisomes: Biology and Importance in Toxicology and Medicine. 1993;313-342 Taylor and Francis, London.
16. Lake B. G., Lewis D. F. V. The CYP4 family. Ioannides C. Cytochromes P450: Metabolic and Toxicological Aspects. 1996;271-297 CRC Press, Boca Raton.
17. Lake B. G., Evans J. G., Cunninghame M. E., Price R. J. Comparison of the hepatic effects of nafenopin and WY-14,643 on peroxisome proliferation and cell replication in the rat and Syrian hamster. Environ. Health Perspect. 101:1993;241-248.
18. Lake B. G., Tredger J. M., Gray T. J. B., Stubberfield C. R., Hodder K. D., Gangolli S. D., Williams R. The effect of peroxisome proliferators on the metabolism and spectral interaction of endogenous substrates of cytochrome P450 in rat hepatic microsomes. Life Sci. 35:1984;2621-2626.
19. Lowry O. H., Rosebrough N. J., Farr A. L., Randall R. J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
20. Marsman D. S., Cattley R. C., Conway J. G., Popp J. A. Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats. Cancer Res. 48:1988;6739-6744.
21. Mirsalis J. C., Tyson C. K., Steinmetz K. L., Loh E. K., Hamilton C. M., Bakke J. P., Spalding J. W. Measurement of unscheduled DNA synthesis and S-phase synthesis in rodent hepatocytes following in vivo treatment: Testing of 24 compounds. Environ. Mol. Mutagen. 14:1989;155-164.
22. National Toxicology Program, 1980, Bioassay of Cinnamyl Anthranilate for Possible Carcinogenicity, U.S. Department of Health and Human Services, NIH, Bethesda, Research Triangle Park, MD, NC.
23. 1, U.S. Department of Health and Human Services, NTP, Research Triangle Park, NC.
24. Omura T., Sato R. The carbon monoxide-binding pigment of liver microsomes. 1. Evidence for its hemoprotein nature. J. Biol. Chem. 239:1964;2370-2378.
25. Opdyke D. L. J. Fragrance raw materials monographs: Cinnamyl anthranilate. Food Chem. Toxicol. 13:1975;751-752.
26. Shelby M. D., Erexson G. L., Hook G. J., Tice R. R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Mol. Mutagen. 21:1993;160-179.
27. Viswalingam A., Caldwell J. Cinnamyl anthranilate causes coinduction of hepatic microsomal and peroxisomal enzymes in mouse but not rat. Toxicol. Appl. Pharmacol. 142:1997;338-347.
28. Viswalingam A., Caldwell J., Fournel S., Schladt L., Oesch F. Hepatic effects of cinnamyl anthranilate resemble those of a peroxisome proliferator in mouse, but not rat. Br. J. Pharmacol. 93:1988;32P.
29. 1. Hum. Exp. Toxicol. 9:1990;339-340.
30. Wild D., King M.-T., Gocke E., Eckhardt K. Study of artificial flavouring substances for mutagenicity in theSalmonella. Food Chem. Toxicol. 21:1983;707-719.