Hypoxia-induced free iron release in the red cells of newborn infants

Acta Paediatrica, International Journal of Paediatrics

Volumn 87, Issue 1, 1998, Pages 77-81

  Buonocore, G ^a   Zani, S ^a   Sargentini, I ^a   Gioia, D ^a   Signorini, C ^a   Bracci, R ^a  

^a UNIVERSITY OF SIENA   (Italy)

Author keywords

Erythrocyte; Free iron; Free radicals; Hypoxia; Newborn infant

Indexed keywords

ARTICLE; BLOOD SAMPLING; CELL DAMAGE; ERYTHROCYTE MEMBRANE; HUMAN; HUMAN CELL; HYPOXIA; IRON KINETICS; LIPID PEROXIDATION; MEMBRANE DAMAGE; OXIDATIVE STRESS; PREMATURITY; PRIORITY JOURNAL; REGRESSION ANALYSIS; RESUSCITATION;

ADULT; ANOXIA; ERYTHROCYTES; FEMALE; FERRITINS; FETAL BLOOD; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; LINEAR MODELS; MALE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; REFERENCE VALUES; REGRESSION ANALYSIS;

EID: 0031911239     PISSN: 08035253     EISSN: None     Source Type: Journal    
DOI: 10.1080/08035259850157912     Document Type: Article

References (31)

1. Jain SK. Membrane lipid peroxidation in erythrocytes of the newborn. CMn Chim Acta 1986; 161: 301-6
2. Lubin B, Oski FA. Red cell metabolism in the newborn infant. IV. Irreversible oxidant-induced injury. J Pediatr 1972; 81: 698-704
3. Gross RT, Bracci R, Rudolph N, Schroeder E, Kochen JA. Hydrogen peroxide toxicity and detoxification in the erythrocytes of newborn infants. Blood 1967; 29: 481-93
4. Buonocore G. Oxidative haemolysis in the newborn: a new approach to an old problem. In: Bellanti JA, Bracci R, Prindull G, Xanthou M, editors. Neonatal haematology and immunology III. Amsterdam: Elsevier Science BV, 1997: 203-8
5. Dorrepaal CA, Berger HM, Benders M JNL, van Zoeren-Grobben D, Van De Bor M, Van Bel F. Nonprotein-bound iron in postasphyxial riperfusion injury of the newborn. Pediatrics 1996; 98: 883-9
6. Etukudo MH, Ramachandra M, Iyer GYN. Methaemoglobin formation and glutathione disappearance in cord blood red cells exposed to acetylphenylhydrazine. Clin Chim Acta 1984; 138: 135-9
7. Shahal Y, Bauminger ER, Zmora E, Katz M, Mazor D, Horn S, et al. Oxidative stress in newborn erythrocytes. Pediatr Res 1991; 29: 119-22
8. Buonocore G, Berni S, Gioia D, Bracci R. Characteristics and functional properties of red cells during the first days of life. Biol Neonate 1991; 60: 137-43
9. Oski FA, Barness LA. Vitamin E deficiency: A previously unrecognized cause of haemolytic anemia in the premature infant. J Pediatr 1967; 70: 211-20
10. Bracci R, Buonocore G, Talluri B, Berni S. Neonatal hyperbilirubinemia. Evidence for a role of the erythrocyte enzyme activities involved in the detoxification of oxygen radicals. Acta Paediatr Scand 1988; 77: 349-56
11. Rice-Evans C, Baysal E. Iron-mediated oxidative stress in erythrocytes. Biochem J 1987; 244: 191-6
12. Puppo A, Halliwell B. Formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Is haemoglobin a biological Fenton reagent? Biochem J 1988; 249: 185-90
13. Ferrali M, Signorini C, Ciccoli L, Comporti M. Iron release and membrane damage in erythrocytes exposed to oxidizing agents, phenylhydrazine, divicine and isouramile. Biochem J 1992; 285: 295-301
14. Gutteridge JMC. Iron promoters of the Fenton reaction and lipid peroxidation can be released from haemoglobin by peroxides. FEBS Lett 1986; 201: 291-5
15. Ferrali M, Signorini C, Ciccoli L, Comporti M. Iron released from an erythrocyte lysate by oxidative stress is diffusible and in redox active form. FEBS Lett 1993; 319: 40-4
16. Boulieu R, Bory C, Baltassat P. High-performance liquid chromatographic determination of hypoxanthine in biological fluid. J Chromatogr 1982; 233: 134-40
17. Halliwell B, Gutteridge JMC, Cross CE. Free radicals, antioxidant, and human disease: where are we now? J Lab Clin Med 1992; 119: 598-620
18. Crichton RR, Charloteaux-Wauters M. Iron transport and storage. Eur J Biochem 1987; 164: 485-506
19. Thomas CE, Morehouse LA, Aust SD. Ferritin and superoxide-dependent lipid peroxidation. J Biol Chem 1985; 260: 3275-80
20. Thomas CE, Aust SD. Release of iron from ferritin by cardiotoxic anthracycline antibiotics. Arch Biochem Biophys 1986; 248: 684-9
21. Crichton RR, Roman F. Iron mobilization from ferritin by chelating agents. J Inorg Biochem 1980; 13: 305-16
22. Ferrali M, Ciccoli L, Comporti M. Allyl alcohol-induced haemolysis and its relation to iron release and lipid peroxidation. Biochem Pharmacol 1989; 38: 1819-25
23. Ciccoli L, Signorini C, Alessandrini C, Ferrali M, Comporti M. Iron release, lipid peroxidation, and morphological alterations of erythrocytes exposed to acrolein and phenylhydrazine. Exp Mol Pathol 1994; 60: 108-18
24. Gutteridge JMC, Halliwell B, Treffry A, Harrison PM, Blake D. Effect of ferritin-containing fractions with different iron loading on lipid peroxidation. Biochem J 1983; 209: 557-60
25. Buonocore G, Gioia D, De Filippo M, Picciolini E, Bracci R. Superoxide anion release by polymorphonuclear leukocytes in whole blood of newborns and mothers during the peripartal period. Pediatr Res 1994; 36: 619-22
26. Winterbourn CC, Stern A. Human red cells scavenge extracellular hydrogen peroxide and inhibit formation of hypochlorous acid and hydroxyl radical. J Clin Invest 1987; 80: 1486-91
27. Rifkind JM, Zhang L, Levy A, Manoharan PT. The hypoxic stress on erythrocytes associated with Superoxide formation. Free Radic Res Commun 1991; 12: 645-52
28. Saugstadt OD. Oxygen toxicity in the neonatal period. Acta Paediatr Scand 1990; 79: 881-92
29. Frank L. Developmental aspects of experimental pulmonary oxygen toxicity. Free Radic Biol Med 1991; 11: 463-94
30. Saugstadt OD. Hypoxanthine as a measurement of hypoxia. Paediatr Res 1975; 9: 158-61
31. Moison RMW, Palinckx JJS, Roest M, Houdkamp E, Berger HM. Induction of lipid peroxidation of pulmonary surfactant by plasma of preterm babies. Lancet 1993; 341: 79-82