Pathogenic autoantibody production requires loss of tolerance against desmoglein 3 in both T and B cells in experimental pemphigus vulgaris

European Journal of Immunology

Volumn 32, Issue 3, 2002, Pages 627-633

  Tsunoda, Kazuyuki ^a   Ota, Takayuki ^a   Suzuki, Harumi ^a,b   Ohyama, Manabu ^a   Nagai, Tetsuo ^a   Nishikawa, Takeji ^a   Amagai, Masayuki ^a   Koyasu, Shigeo ^a  

^a KEIO UNIVERSITY   (Japan)

^b YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Autoantibody; Disease model; Knockout mouse; Self tolerance

Indexed keywords

AUTOANTIBODY; DESMOGLEIN; IMMUNOGLOBULIN G; PEMPHIGUS ANTIBODY; RECOMBINANT PROTEIN;

ACANTHOLYSIS; ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; EROSION; IMMUNOLOGICAL TOLERANCE; MOUSE; NONHUMAN; PEMPHIGUS VULGARIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURIFICATION; SPLEEN CELL; T LYMPHOCYTE;

ADOPTIVE TRANSFER; ANIMALS; AUTOANTIBODIES; AUTOANTIGENS; B-LYMPHOCYTE SUBSETS; CADHERINS; CELL LINE; CROSSES, GENETIC; DESMOGLEIN 3; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; EPIDERMIS; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNIZATION; IMMUNOGLOBULIN G; KERATINOCYTES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOUTH MUCOSA; NUCLEAR PROTEINS; PEMPHIGUS; PHENOTYPE; RECOMBINANT FUSION PROTEINS; SELF TOLERANCE; T-LYMPHOCYTE SUBSETS;

EID: 0036209714     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200203)32:3<627::AID-IMMU627>3.0.CO;2-1     Document Type: Article

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