Acetaminophen-induced proliferation of estrogen-responsive breast cancer cells is associated with increases in c-myc RNA expression and NF-κB activity

Toxicological Sciences

Volumn 66, Issue 2, 2002, Pages 233-243

  Gadd, Samantha L ^a   Hobbs, Gerry ^a   Miller, Michael R ^a,b,c  

^a WEST VIRGINIA UNIVERSITY   (United States)

^b NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^c WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

Acetaminophen; c myc gene; Cell cycle; Estrogen receptor; NF B

Indexed keywords

CYCLIN D1; ESTROGEN; ESTROGEN RECEPTOR; GLUTAMATE DECARBOXYLASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYC PROTEIN; PARACETAMOL; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN C FOS; PROTEIN MCL 1; PROTEIN P21; PROTEIN P53; RIBONUCLEASE; RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

ARTICLE; BREAST CANCER; CANCER CELL; CELL PROLIFERATION; CELL STRAIN MCF 7; CELL TYPE; CONTROLLED STUDY; ENDOMETRIUM CARCINOMA; GEL MOBILITY SHIFT ASSAY; GENE ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPOTHESIS; MITOGENESIS; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; RIBONUCLEASE PROTECTION ASSAY; TIME;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; BREAST NEOPLASMS; CELL DIVISION; ESTRADIOL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASMS, HORMONE-DEPENDENT; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-MYC; RECEPTORS, ESTRADIOL; RNA, MESSENGER; TUMOR CELLS, CULTURED;

MINK CELL FOCUS-FORMING VIRUS;

EID: 0036204416     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/66.2.233     Document Type: Article

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