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Volumn 47, Issue 2, 1998, Pages 181-193

Induction of p21 (CIP1/WAF1/SID1) by estradiol in a breast epithelial cell line transfected with the recombinant estrogen receptor gene: A possible mechanism for a negative regulatory role of estradiol

Author keywords

Estradiol; p21; Recombinant estrogen receptor

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; ESTRADIOL; ESTROGEN RECEPTOR; MESSENGER RNA; N BUTYL 11 (3,17BETA DIHYDROXYESTRA 1,3,5(10) TRIEN 7ALPHA YL) N METHYLUNDECANAMIDE; PROTEIN P21;

EID: 0031973862     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005925931215     Document Type: Article
Times cited : (20)

References (75)
  • 1
    • 0024545638 scopus 로고
    • Gene regulation by steroid hormones
    • Beato M: Gene regulation by steroid hormones. Cell 56: 335-344, 1989
    • (1989) Cell , vol.56 , pp. 335-344
    • Beato, M.1
  • 2
    • 0024396320 scopus 로고
    • Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins
    • Mitchell PJ, Tjian R: Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science 245: 371-378, 1989
    • (1989) Science , vol.245 , pp. 371-378
    • Mitchell, P.J.1    Tjian, R.2
  • 3
    • 0023913120 scopus 로고
    • The steroid and thyroid hormone receptor superfamily
    • Evans RM: The steroid and thyroid hormone receptor superfamily. Science 240: 889-895, 1988
    • (1988) Science , vol.240 , pp. 889-895
    • Evans, R.M.1
  • 4
    • 0023836871 scopus 로고
    • Estrogens as a cause of human cancer: The Richard and Hinda Rosenthal Foundation Award lecture
    • Henderson BE, Ross R, Bernstein L: Estrogens as a cause of human cancer: the Richard and Hinda Rosenthal Foundation Award lecture. Cancer Res 48: 246-253, 1988
    • (1988) Cancer Res , vol.48 , pp. 246-253
    • Henderson, B.E.1    Ross, R.2    Bernstein, L.3
  • 5
    • 0026519439 scopus 로고
    • Hormonal aspects of breast cancer: Growth factors, drugs and stromal interactions
    • Clarke R, Dickson RB, Lippman ME: Hormonal aspects of breast cancer: Growth factors, drugs and stromal interactions. Crit Rev Oncology-Hemat 12: 1-23, 1992
    • (1992) Crit Rev Oncology-Hemat , vol.12 , pp. 1-23
    • Clarke, R.1    Dickson, R.B.2    Lippman, M.E.3
  • 6
    • 0026685685 scopus 로고
    • The strategic use of antiestrogens to control the development and growth of breast cancer
    • Jordan VC: The strategic use of antiestrogens to control the development and growth of breast cancer. Cancer 70: 977-982, 1992
    • (1992) Cancer , vol.70 , pp. 977-982
    • Jordan, V.C.1
  • 7
    • 0027401411 scopus 로고
    • The future of new pure antiestrogens in clinical breast cancer
    • Wakeling AE: The future of new pure antiestrogens in clinical breast cancer. Breast Cancer Res Treat 25: 1-9, 1993
    • (1993) Breast Cancer Res Treat , vol.25 , pp. 1-9
    • Wakeling, A.E.1
  • 8
    • 0028283503 scopus 로고
    • Molecular mechanisms of action of steroid/thyroid receptor superfamily members
    • Tsai M-J, O'Malley BW: Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu Rev Biochem 63: 451-486, 1994
    • (1994) Annu Rev Biochem , vol.63 , pp. 451-486
    • Tsai, M.-J.1    O'Malley, B.W.2
  • 9
    • 0025806284 scopus 로고
    • Superfamily of nuclear receptors: Positive and negative regulators of gene expression
    • Wahli W, Martinez E: Superfamily of nuclear receptors: positive and negative regulators of gene expression. FASEB J 5: 2243-2249, 1991
    • (1991) FASEB J , vol.5 , pp. 2243-2249
    • Wahli, W.1    Martinez, E.2
  • 10
    • 0024323891 scopus 로고
    • Direct effects of estrogen on c-fos and c-myc protooncogene expression and cellular proliferation in human breast cancer cells
    • van der Burg B, Selm-Miltenburg AJP, de Laat SW, van Zoelen EJJ: Direct effects of estrogen on c-fos and c-myc protooncogene expression and cellular proliferation in human breast cancer cells. Mol Cell Endocrinol 64: 223-228, 1989
    • (1989) Mol Cell Endocrinol , vol.64 , pp. 223-228
    • Van Der Burg, B.1    Selm-Miltenburg, A.J.P.2    De Laat, S.W.3    Van Zoelen, E.J.J.4
  • 11
    • 0026735224 scopus 로고
    • Mechanism of estrogen activation of c-myc oncogene expression
    • Dubik D, Shiu RP: Mechanism of estrogen activation of c-myc oncogene expression. Oncogene 7: 1587-1594, 1992
    • (1992) Oncogene , vol.7 , pp. 1587-1594
    • Dubik, D.1    Shiu, R.P.2
  • 12
    • 0029064780 scopus 로고
    • Suppression of c-myc oncogene expression by a polyamine-complexed triplex forming oligonucleotide in estrogen-responsive MCF-7 breast cancer cells
    • Thomas TJ, Faaland CA, Gallo MA, Thomas T: Suppression of c-myc oncogene expression by a polyamine-complexed triplex forming oligonucleotide in estrogen-responsive MCF-7 breast cancer cells. Nucl Acids Res 23: 3594-3599, 1995
    • (1995) Nucl Acids Res , vol.23 , pp. 3594-3599
    • Thomas, T.J.1    Faaland, C.A.2    Gallo, M.A.3    Thomas, T.4
  • 13
    • 0028265460 scopus 로고
    • Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: Therapeutic implications
    • Thomas T, Thomas TJ: Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: Therapeutic implications. Breast Cancer Res Treat 29: 189-201, 1993
    • (1993) Breast Cancer Res Treat , vol.29 , pp. 189-201
    • Thomas, T.1    Thomas, T.J.2
  • 14
    • 0024454741 scopus 로고
    • The 5′-flanking region of the PS2 gene contains a complex enhancer region responsive to oestrogen, epidermal growth factor, a tumor promoter (TPA), the c-Ha-ras oncoprotein and the c-jun protein
    • Nunez A-M, Berry M, Imler J-L, Chambon P: The 5′-flanking region of the PS2 gene contains a complex enhancer region responsive to oestrogen, epidermal growth factor, a tumor promoter (TPA), the c-Ha-ras oncoprotein and the c-jun protein. EMBO J 8: 823-829, 1989
    • (1989) EMBO J , vol.8 , pp. 823-829
    • Nunez, A.-M.1    Berry, M.2    Imler, J.-L.3    Chambon, P.4
  • 15
    • 0027299883 scopus 로고
    • Growth factor, steroid and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression
    • Musgrove EA, Hamilton JA, Lee CS, Sweeny KJ, Watts CKW, Sutherland RL: Growth factor, steroid and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression. Mol Cell Biol 13: 3577-3587, 1993
    • (1993) Mol Cell Biol , vol.13 , pp. 3577-3587
    • Musgrove, E.A.1    Hamilton, J.A.2    Lee, C.S.3    Sweeny, K.J.4    Watts, C.K.W.5    Sutherland, R.L.6
  • 16
    • 0026450958 scopus 로고
    • Activation of estrogen receptor transfected into a receptor-negative breast cancer cell line decrease the metastatic and invasive potential of the cells
    • Garcia M, Derocq D, Freiss G, Rochefort H: Activation of estrogen receptor transfected into a receptor-negative breast cancer cell line decrease the metastatic and invasive potential of the cells. Proc Natl Acad Sci USA 89: 11538-11542, 1992
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11538-11542
    • Garcia, M.1    Derocq, D.2    Freiss, G.3    Rochefort, H.4
  • 17
    • 0027484427 scopus 로고
    • Estrogen inhibits the growth of estrogen receptor-negative, but not estrogen receptor-positive, human mammary epithelial cells expressing a recombinant estrogen receptor
    • Zajchowski DA, Sager R, Webster L: Estrogen inhibits the growth of estrogen receptor-negative, but not estrogen receptor-positive, human mammary epithelial cells expressing a recombinant estrogen receptor. Cancer Res 53: 5004-5011, 1993
    • (1993) Cancer Res , vol.53 , pp. 5004-5011
    • Zajchowski, D.A.1    Sager, R.2    Webster, L.3
  • 18
    • 0026520381 scopus 로고
    • Growth regulation of estrogen receptor-negative breast cancer cells transfected with complementary DNAs for estrogen receptor
    • Jiang S-Y, Jordan VC: Growth regulation of estrogen receptor-negative breast cancer cells transfected with complementary DNAs for estrogen receptor. J Natl Cancer Inst 84: 580-591, 1992
    • (1992) J Natl Cancer Inst , vol.84 , pp. 580-591
    • Jiang, S.-Y.1    Jordan, V.C.2
  • 19
    • 0028222533 scopus 로고
    • Down-modulation of interleukin-6 gene expression by 17β-estradiol in the absence of high affinity binding by the estrogen receptor
    • Ray A, Prefontaine K, Ray P: Down-modulation of interleukin-6 gene expression by 17β-estradiol in the absence of high affinity binding by the estrogen receptor. J Biol Chem 269: 12940-12946, 1994
    • (1994) J Biol Chem , vol.269 , pp. 12940-12946
    • Ray, A.1    Prefontaine, K.2    Ray, P.3
  • 20
    • 0025013048 scopus 로고
    • Construction of cell lines that express high levels of the human estrogen receptor that are killed by estrogens
    • Kushner PJ, Hort E, Shine J, Baxter JD, Greene GL: Construction of cell lines that express high levels of the human estrogen receptor that are killed by estrogens. Mol Endocrinol 4: 1465-1473, 1990
    • (1990) Mol Endocrinol , vol.4 , pp. 1465-1473
    • Kushner, P.J.1    Hort, E.2    Shine, J.3    Baxter, J.D.4    Greene, G.L.5
  • 22
    • 0025331053 scopus 로고
    • Cell kinetics of estradiol stimulated long-term phenol red withdrawn cultured breast cancer cells
    • Revillion F, Lassalle B, Vandewale B, Lefebvre J: Cell kinetics of estradiol stimulated long-term phenol red withdrawn cultured breast cancer cells. Anticancer Res 10: 1067-1070, 1990
    • (1990) Anticancer Res , vol.10 , pp. 1067-1070
    • Revillion, F.1    Lassalle, B.2    Vandewale, B.3    Lefebvre, J.4
  • 23
    • 0022966918 scopus 로고
    • Cell cycle analysis of estrogen stimulation and antiestrogen inhibition of growth of the human breast cancer cell line
    • Lykkesfeldt AE, Larsen JK, Christensen IJ: Cell cycle analysis of estrogen stimulation and antiestrogen inhibition of growth of the human breast cancer cell line. Breast Cancer Res Treat 7: S83-90, 1986
    • (1986) Breast Cancer Res Treat , vol.7
    • Lykkesfeldt, A.E.1    Larsen, J.K.2    Christensen, I.J.3
  • 24
    • 0024505761 scopus 로고
    • Points of action of estrogen antagonists and a calmodulin antagonist within the MCF-7 human breast cancer cell cycle
    • Musgrove EA, Wakeling AE, Sutherland RL: Points of action of estrogen antagonists and a calmodulin antagonist within the MCF-7 human breast cancer cell cycle. Cancer Res 49: 2398-2404, 1989
    • (1989) Cancer Res , vol.49 , pp. 2398-2404
    • Musgrove, E.A.1    Wakeling, A.E.2    Sutherland, R.L.3
  • 25
    • 0023224070 scopus 로고
    • Mode of action of estrogen on cell proliferative kinetics in CAMA-1 cells. I. Effects of serum and estrogen
    • Leung BS, Potter AH: Mode of action of estrogen on cell proliferative kinetics in CAMA-1 cells. I. Effects of serum and estrogen. Cancer Investigation 5: 187-194, 1987
    • (1987) Cancer Investigation , vol.5 , pp. 187-194
    • Leung, B.S.1    Potter, A.H.2
  • 26
    • 0028205818 scopus 로고
    • Regulation of cyclin B1 by estradiol and polyamines in MCF-7 breast cancer cells
    • Thomas T, Thomas TJ: Regulation of cyclin B1 by estradiol and polyamines in MCF-7 breast cancer cells. Cancer Res 54: 1077-1084, 1994
    • (1994) Cancer Res , vol.54 , pp. 1077-1084
    • Thomas, T.1    Thomas, T.J.2
  • 27
    • 0026693966 scopus 로고
    • Animal cell cycles and their control
    • Norbury C, Nurse P: Animal cell cycles and their control. Annu Rev Biochem 61: 441-470, 1992
    • (1992) Annu Rev Biochem , vol.61 , pp. 441-470
    • Norbury, C.1    Nurse, P.2
  • 28
    • 0027938209 scopus 로고
    • Cyclins and cancer II: Cyclin D and CDK inhibitors come of age
    • Hunter T, Pines J: Cyclins and cancer II: cyclin D and CDK inhibitors come of age. Cell 79: 573-582, 1994
    • (1994) Cell , vol.79 , pp. 573-582
    • Hunter, T.1    Pines, J.2
  • 29
    • 0028266430 scopus 로고
    • Cyclins and cancer: Wheels within wheels
    • Steel M: Cyclins and cancer: wheels within wheels. Lancet 343: 931-932, 1994
    • (1994) Lancet , vol.343 , pp. 931-932
    • Steel, M.1
  • 30
    • 0027768579 scopus 로고
    • Braking the cycle
    • Hunter T: Braking the cycle. Cell 75: 839-841, 1993
    • (1993) Cell , vol.75 , pp. 839-841
    • Hunter, T.1
  • 32
    • 0027496935 scopus 로고
    • The p21 cdk-interacting protein cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ: The p21 cdk-interacting protein cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75: 805-816, 1993
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 34
    • 0028342664 scopus 로고
    • Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
    • Noda A, Ning Y, Venable SF, Pereira-Smith OM, Smith JR: Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp Cell Res 211: 90-98, 1994
    • (1994) Exp Cell Res , vol.211 , pp. 90-98
    • Noda, A.1    Ning, Y.2    Venable, S.F.3    Pereira-Smith, O.M.4    Smith, J.R.5
  • 35
    • 0027530449 scopus 로고
    • Redundant cyclin overexpression and gene amplification in breast cancer cells
    • Keyomarsi K, Pardee A: Redundant cyclin overexpression and gene amplification in breast cancer cells. Proc Natl Acad Sci USA 90: 1112-1116, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1112-1116
    • Keyomarsi, K.1    Pardee, A.2
  • 38
    • 0028108451 scopus 로고
    • Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle
    • Musgrove EA, Lee CSL, Buckley MF, Sutherland RL: Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle. Proc Natl Acad Sci USA 91: 8022-8026, 1994
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8022-8026
    • Musgrove, E.A.1    Lee, C.S.L.2    Buckley, M.F.3    Sutherland, R.L.4
  • 40
    • 0029665447 scopus 로고    scopus 로고
    • 17β-Estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G(1)-arrested human breast cancer cells
    • Altucci L, Addeo R, Cicatiello L, Dauvois S, Parker MG, Truss M, Beato M, Sica V, Besciani F. Weisz A: 17β-Estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G(1)-arrested human breast cancer cells. Oncogene 12: 2315-2324, 1996
    • (1996) Oncogene , vol.12 , pp. 2315-2324
    • Altucci, L.1    Addeo, R.2    Cicatiello, L.3    Dauvois, S.4    Parker, M.G.5    Truss, M.6    Beato, M.7    Sica, V.8    Besciani, F.9    Weisz, A.10
  • 41
    • 0027440552 scopus 로고
    • Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes
    • Zhang H, Xiong Y, Death D: Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes. Mol Biol Cell 4: 897-906, 1993
    • (1993) Mol Biol Cell , vol.4 , pp. 897-906
    • Zhang, H.1    Xiong, Y.2    Death, D.3
  • 45
    • 0027987170 scopus 로고
    • Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53
    • Jiang H, Lin J, Su ZZ, Collart FR, Huberman E, Fisher PB: Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53. Oncogene 9: 3397-3406, 1994
    • (1994) Oncogene , vol.9 , pp. 3397-3406
    • Jiang, H.1    Lin, J.2    Su, Z.Z.3    Collart, F.R.4    Huberman, E.5    Fisher, P.B.6
  • 46
    • 0028169236 scopus 로고
    • p21-containing cyclin kinases exist in both active and inactive states
    • Zhang H, Hannon GJ, Beach D: p21-containing cyclin kinases exist in both active and inactive states. Genes Dev 8: 1750-1758, 1994
    • (1994) Genes Dev , vol.8 , pp. 1750-1758
    • Zhang, H.1    Hannon, G.J.2    Beach, D.3
  • 47
    • 0028352434 scopus 로고
    • The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
    • Waga S, Hannon GJ, Beach D, Stillman B: The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 369: 574-578, 1994
    • (1994) Nature , vol.369 , pp. 574-578
    • Waga, S.1    Hannon, G.J.2    Beach, D.3    Stillman, B.4
  • 48
    • 0027981476 scopus 로고
    • CdK-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalysed by the DNA polymerase δ holoenzyme
    • Flores-Rozas H, Kelman Z, Dean FB, Pan Z-Q, Harper JW, Elledge SJ, O'Donnell M, Hurwitz J: CdK-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalysed by the DNA polymerase δ holoenzyme. Proc Natl Acad Sci 91: 8655-8659, 1994
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 8655-8659
    • Flores-Rozas, H.1    Kelman, Z.2    Dean, F.B.3    Pan, Z.-Q.4    Harper, J.W.5    Elledge, S.J.6    O'Donnell, M.7    Hurwitz, J.8
  • 50
    • 0024440781 scopus 로고
    • The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties
    • Tora L, Mullick A, Metzger D, Ponglikitmongkol M, Park I, Chambon P: The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties. EMBO J 8: 1981-1986, 1989
    • (1989) EMBO J , vol.8 , pp. 1981-1986
    • Tora, L.1    Mullick, A.2    Metzger, D.3    Ponglikitmongkol, M.4    Park, I.5    Chambon, P.6
  • 51
    • 85069062689 scopus 로고
    • Estrogenic stimulation of ornithine decarboxylase (ODC) in MCF-10A breast epithelial cells transfected with estrogen receptor (ER) gene
    • Faaland CA, Thomas TJ, Watkins LF, Thomas T: Estrogenic stimulation of ornithine decarboxylase (ODC) in MCF-10A breast epithelial cells transfected with estrogen receptor (ER) gene. Proc Am Assoc Cancer Res 35: 260, 1994
    • (1994) Proc Am Assoc Cancer Res , vol.35 , pp. 260
    • Faaland, C.A.1    Thomas, T.J.2    Watkins, L.F.3    Thomas, T.4
  • 52
    • 0019223765 scopus 로고
    • Processing of prolactin by human breast cancer cells in king-term tissue culture
    • Shiu RP: Processing of prolactin by human breast cancer cells in king-term tissue culture. J Biol Chem 255: 4278-4281, 1980
    • (1980) J Biol Chem , vol.255 , pp. 4278-4281
    • Shiu, R.P.1
  • 53
    • 0019810824 scopus 로고
    • Calcitonin induction of a persistent activated state of adenylate cyclase in human breast cancer cells (T-47D)
    • Lamps SJ, Findlay DM, Moseley JM, Martin TJ: Calcitonin induction of a persistent activated state of adenylate cyclase in human breast cancer cells (T-47D). J Biol Chem 256: 12269-12274, 1981
    • (1981) J Biol Chem , vol.256 , pp. 12269-12274
    • Lamps, S.J.1    Findlay, D.M.2    Moseley, J.M.3    Martin, T.J.4
  • 55
    • 0026460218 scopus 로고
    • An estrogen receptor positive MCF-7 clone that is resistant to antiestrogens and estradiol
    • Jiang SY, Wolf DM, Yingling JM, Chang C, Jordan VC: An estrogen receptor positive MCF-7 clone that is resistant to antiestrogens and estradiol. Mol Cell Endocrinol 90: 77-86, 1992
    • (1992) Mol Cell Endocrinol , vol.90 , pp. 77-86
    • Jiang, S.Y.1    Wolf, D.M.2    Yingling, J.M.3    Chang, C.4    Jordan, V.C.5
  • 56
    • 0017645944 scopus 로고
    • Two syngeneic cell lines from human breast tissue: The aneuploid mammary epithelial (Hs578T) and the diploid myoepithelial (Hs578 Bst) cell lines
    • Hackett AJ, Smith HS, Springer EL, Owens RB, Nelson-Rees WA, Riggs JL, Gardner MB: Two syngeneic cell lines from human breast tissue: the aneuploid mammary epithelial (Hs578T) and the diploid myoepithelial (Hs578 Bst) cell lines. J Natl Cancer Inst 58: 1795-1806, 1977
    • (1977) J Natl Cancer Inst , vol.58 , pp. 1795-1806
    • Hackett, A.J.1    Smith, H.S.2    Springer, E.L.3    Owens, R.B.4    Nelson-Rees, W.A.5    Riggs, J.L.6    Gardner, M.B.7
  • 58
    • 0028869550 scopus 로고
    • Inhibition of epidermal growth factor-stimulated EGF receptor tyrosine kinase activity in A431 human epidermoid carcinoma cells by polyamines
    • Faaland CA, Laskin JD, Thomas TJ: Inhibition of epidermal growth factor-stimulated EGF receptor tyrosine kinase activity in A431 human epidermoid carcinoma cells by polyamines. Cell Growth Different 6: 115-121, 1995
    • (1995) Cell Growth Different , vol.6 , pp. 115-121
    • Faaland, C.A.1    Laskin, J.D.2    Thomas, T.J.3
  • 59
    • 0026395885 scopus 로고
    • A potent specific pure antiestrogen with clinical potential
    • Wakeling AE, Dukes M, Bowler J: A potent specific pure antiestrogen with clinical potential. Cancer Res 51: 3867-3873, 1991
    • (1991) Cancer Res , vol.51 , pp. 3867-3873
    • Wakeling, A.E.1    Dukes, M.2    Bowler, J.3
  • 60
    • 0026472371 scopus 로고
    • Identification of a negative regulatory function for steroid receptors
    • McDonnell DP, Vegeto E, O'Malley BW: Identification of a negative regulatory function for steroid receptors. Proc Natl Acad Sci USA 89: 10563-10567, 1992
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10563-10567
    • McDonnell, D.P.1    Vegeto, E.2    O'Malley, B.W.3
  • 62
    • 0028363519 scopus 로고
    • p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21
    • Toyoshima H, Hunter T: p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78: 67-74, 1994
    • (1994) Cell , vol.78 , pp. 67-74
    • Toyoshima, H.1    Hunter, T.2
  • 63
    • 0028168242 scopus 로고
    • 1NK4B is a potential effector of the TGF-β-induced cell cycle arrest
    • 1NK4B is a potential effector of the TGF-β-induced cell cycle arrest. Nature 371: 257-261, 1994
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 64
    • 0028227197 scopus 로고
    • A novel inhibitor of cyclin-Cdk activity directed in transforming growth factor β-arrested epithelial cells
    • Slingerland JM, Hengst L, Pan CH, Alexander D, Stampfer MR, Reed SI: A novel inhibitor of cyclin-Cdk activity directed in transforming growth factor β-arrested epithelial cells. Mol Cell Biol 14: 3683-3694, 1994
    • (1994) Mol Cell Biol , vol.14 , pp. 3683-3694
    • Slingerland, J.M.1    Hengst, L.2    Pan, C.H.3    Alexander, D.4    Stampfer, M.R.5    Reed, S.I.6
  • 66
    • 0005996498 scopus 로고
    • Epidermal growth factor (EGF) stimulates the expression of p21 (CIP1/ WAF1) cyclin dependent kinase (CDK) inhibitor in MDA-MB-468 breast cancer cells
    • Jiang A, Thomas TJ, Faaland CA, Thomas T: Epidermal growth factor (EGF) stimulates the expression of p21 (CIP1/ WAF1) cyclin dependent kinase (CDK) inhibitor in MDA-MB-468 breast cancer cells. Proc Am Assoc Cancer Res 36: 580, 1995
    • (1995) Proc Am Assoc Cancer Res , vol.36 , pp. 580
    • Jiang, A.1    Thomas, T.J.2    Faaland, C.A.3    Thomas, T.4
  • 67
    • 85069077674 scopus 로고
    • Inactivation of the cell cycle inhibitory protein, p21 (CIP1/ WAF1) during chemical carcinogenesis of normal breast epithelial cells
    • Sysounthone V, Thomas T, Shah N, Faaland CA, Thomas TJ: Inactivation of the cell cycle inhibitory protein, p21 (CIP1/ WAF1) during chemical carcinogenesis of normal breast epithelial cells. Proc Am Assoc Cancer Res 36: 580, 1995
    • (1995) Proc Am Assoc Cancer Res , vol.36 , pp. 580
    • Sysounthone, V.1    Thomas, T.2    Shah, N.3    Faaland, C.A.4    Thomas, T.J.5
  • 68
    • 0028846193 scopus 로고
    • Sequence and characterization of a coactivator for the steroid hormone receptor superfamily
    • Onate SA, Tsai SY, Tsai M-J, O'Malley BW: Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270: 1354-1357, 1995
    • (1995) Science , vol.270 , pp. 1354-1357
    • Onate, S.A.1    Tsai, S.Y.2    Tsai, M.-J.3    O'Malley, B.W.4
  • 69
    • 0024296177 scopus 로고
    • A 13 bp palindrome is a functional estrogen responsive element and interacts specifically with estrogen receptor
    • Klein-Hitpass L, Ryffel GU, Heitlinger E, Cato ACB: A 13 bp palindrome is a functional estrogen responsive element and interacts specifically with estrogen receptor. Nucl Acids Res 16: 647-663, 1988
    • (1988) Nucl Acids Res , vol.16 , pp. 647-663
    • Klein-Hitpass, L.1    Ryffel, G.U.2    Heitlinger, E.3    Cato, A.C.B.4
  • 70
    • 0028068422 scopus 로고
    • Novel estrogen response elements identified by genetic selection in yeast are differentially responsive to estrogens and anti-estrogens in mammalian cells
    • Dana SL, Hoener PA, Wheeler DA, Lawrence CB, McDonnell DP: Novel estrogen response elements identified by genetic selection in yeast are differentially responsive to estrogens and anti-estrogens in mammalian cells. Mol Endocrinol 8: 1193-1207, 1994
    • (1994) Mol Endocrinol , vol.8 , pp. 1193-1207
    • Dana, S.L.1    Hoener, P.A.2    Wheeler, D.A.3    Lawrence, C.B.4    McDonnell, D.P.5
  • 71
    • 0027980338 scopus 로고
    • Identification of multiple, widely spaced estrogen-responsive regions of the rat progesterone receptor gene
    • Kraus WL, Montano MM, Katzenellenbogen BS: Identification of multiple, widely spaced estrogen-responsive regions of the rat progesterone receptor gene. Mol Endocrinol 8: 952-969, 1994
    • (1994) Mol Endocrinol , vol.8 , pp. 952-969
    • Kraus, W.L.1    Montano, M.M.2    Katzenellenbogen, B.S.3
  • 72
    • 0027319423 scopus 로고
    • Modulation of the ligand-independent activation of the human estrogen receptor by hormone and antihormone
    • Smith CL, Conneely OM, O'Malley BW: Modulation of the ligand-independent activation of the human estrogen receptor by hormone and antihormone. Proc Natl Acad Sci USA 90: 6120-6124, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6120-6124
    • Smith, C.L.1    Conneely, O.M.2    O'Malley, B.W.3
  • 74
    • 0028036401 scopus 로고
    • The interaction of human estrogen receptor with DNA is modulated by receptor-associated proteins
    • Landel CC, Kushner PJ, Greene GL: The interaction of human estrogen receptor with DNA is modulated by receptor-associated proteins. Mol Endocrinol 8: 1407-1419, 1994
    • (1994) Mol Endocrinol , vol.8 , pp. 1407-1419
    • Landel, C.C.1    Kushner, P.J.2    Greene, G.L.3
  • 75
    • 0028233383 scopus 로고
    • Estrogen receptor-associated proteins: Possible mediators of hormone-induced transcription
    • Halachmi S, Marden E, Martin G, MacKay H, Abbondanza C, Brown M: Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription. Science 264: 1455-1458, 1994
    • (1994) Science , vol.264 , pp. 1455-1458
    • Halachmi, S.1    Marden, E.2    Martin, G.3    MacKay, H.4    Abbondanza, C.5    Brown, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.