Myocardial gene therapy

Archives des Maladies du Coeur et des Vaisseaux

Volumn 95, Issue 3, 2002, Pages 197-203

  Mercadier, J J ^a,b   Logeart, D ^b,c  

^a BICHAT HOSPITAL   (France)

^b INSERM   (France)

^c BEAUJON HOSPITAL   (France)

Author keywords

Biotheraphies; Gene therapy; Heart failure; Myocardium

Indexed keywords

ADENOVIRUS VECTOR; ANGIOGENIC FACTOR;

CARDIOMYOPATHY; CORONARY ARTERY; GENE MUTATION; GENE THERAPY; GENETIC TRANSFECTION; HEART FAILURE; HEART PERFORMANCE; ISCHEMIC HEART DISEASE; MYOCARDIAL DISEASE; NONHUMAN; REVIEW;

EID: 0036201677     PISSN: 00039683     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (39)

1. Angiogenesis in ischemic heart disease
2. Gene therapy for therapeutic myocardial angiogenesis: A promising synthesis of two emerging technologies
3. Somatic gene therapy in the cardiovascular system
4. Widespread long-term gene transfer to mouse skeletal muscle and heart
5. Adenoviral gene transfer of SERCA2a improves left-ventricular function in aorticbanded rats in transition to heart failure
6. Evidence that human cardiac myocytes divide after myocardial infarction
7. Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo
8. Efficient and stable transduction of cardiomyocytes after intramyocardial injection or intracoronary perfusion with recombinant adeno-associated virus vectors
9. Adeno-associated viral vector mediated vascular endothelial growth factor gene transfer induces neovascular formation in ischemic heart
10. A high-titer lentiviral production system mediates efficient transduction of differentiated cells including beating cardiac myocytes
11. Augmentation of myocardial transfection using TerplexDNA, a novel gene delivery system
12. Myocardial injury-induced fibroblast proliferation facilitates retroviral-mediated gene transfer to the rat heart in vivo
13. Expression of recombinant genes in myocardium in vivo after direct injection of DNA
14. Efficient gene transfer to myocardium by direct injection of adenovirus vectors
15. Direct in vivo gene transfer into porcine myocardium using replication-deficient adenoviral vectors
16. Electromagnetic guidance for catheter-based transendocardial injection: A platform for intramyocardial anagiogenesis therapy. Results in normal and ischemic porcine models
17. Intrapericardial administration of adenovirus for gene transfer
18. Gene delivery to the myocardium by intrapericardial injection
19. Angiogenic potential of perivascularly delivered eFGF in a porcine model of chronic myocardial ischemia
20. Efficient catheter-mediated gene transfer into the heart using replication-defective adenovirus
21. Safety and efficiency of in vivo gene transfer into the porcine with replication-deficient, recombinant adenovirus vectors
22. Increased efficiency of gene transfer to cardiac myocytes with recombinant adenovirus by altering the endothelial barrier permeability
23. Ultrarapid, highly efficient viral gene transfer to the heart
24. Acceleration of widespread adenoviral gene transfer to intact rabbit hearts by coronary perfusion with low calcium and serotonin
25. Highly efficient adenovirus-mediated gene transfer to cardiac myocytes after single-pass coronary delivery
26. Modulation of ventricular function through gene transfer in vivo
27. How to optimize gene transfer to cardiac myocytes: Mechanical or pharmacological procedures?
28. Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veins
29. Echocardiographic destruction of albumin microbubbles directs gene delivery to the myocardium
30. Progression from cardiac hypertrophy to heart failure
31. Prevention of cardiac hypertrophy by calcineurin inhibition
32. Physiological effects of adenoviral gene transfer of sarcoplasmic reticulum calcium ATPase in isolated rat myocytes
33. Adenoviral SERCA1a gene transfer to adult rat ventricular myocytes induces physiological changes in calcium handling
34. Restoration of diastolic function in senescent rat hearts through adenoviral gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase
35. A dose-dependent increase in mortality with vesnarinone among patients with severe heart failure
36. Improvement in survival and cardiac metabolism after gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase in a rat model of heart failure
37. Adenovirus mediated expression of a voltage-gated potassium channel in vitro (rat cardiac myocyte) and I (rat liver). A novel strategy for modifying excitability
38. Reversal of potassium channel deficiency in cells from failing hearts by adenoviral gene transfer: A prototype for gene therapy for disorders of cardiac excitability and contractility
39. Ca2+-desensitizing effect of a deletion mutation in DK210 in cardiac troponin T that causes familial dilated cardiomyopathy