Regulation of nitrogen fixation in Klebsiella pneumoniae and Azotobacter vinelandii: NifL, transducing two environmental signals to the nif transcriptional activator NifA

Journal of Molecular Microbiology and Biotechnology

Volumn 4, Issue 3, 2002, Pages 235-242

  Schmitz, Ruth A ^a   Klopprogge, Kai ^a   Grabbe, Roman ^a  

^a Inst fuer Mikrobiologie und Genetik   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE NUCLEOTIDE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; AMMONIA; BACTERIAL PROTEIN; HOLOENZYME; NITROGEN; NITROGENASE; OXYGEN; RNA POLYMERASE; TRANSCRIPTION FACTOR;

AZOTOBACTER VINELANDII; CARBOXY TERMINAL SEQUENCE; CONFERENCE PAPER; CONTROLLED STUDY; ENERGY CONSUMPTION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SYNTHESIS; GENETIC TRANSCRIPTION; HYDROLYSIS; IN VITRO STUDY; IN VIVO STUDY; KLEBSIELLA PNEUMONIAE; NITROGEN FIXATION; NONHUMAN; OPERON; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; REDUCTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

AZOTOBACTER VINELANDII; BACTERIAL PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; KLEBSIELLA PNEUMONIAE; NITROGEN FIXATION; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

AZOTOBACTER; AZOTOBACTER VINELANDII; BACTERIA (MICROORGANISMS); KLEBSIELLA; KLEBSIELLA PNEUMONIAE;

EID: 0036198623     PISSN: 14641801     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (75)

1. Two residues in the T-loop of Klebsiella pneumoniae GlnK determine NifL-dependent nitrogen control of nif gene expression
2. Studies on the roles of GlnK and GlnB in regulating Klebsiella pneumoniae NifL-dependent nitrogen control
3. Deletion analysis of the nitrogen fixation regulatory gene nifL of Klebsiella pneumoniae
4. Control of Azospirillum brasilense NifA activity by P(II): Effect of replacing Tyr residues of the NifA N-terminal domain on NifA activity
5. Purification and in vitro activities of the native nitrogen fixation control proteins NifA and NifL
6. Concerted inhibition of the transcriptional activation functions of the enhancer-binding protein NIFA by the anti-activator NIFL
7. Fe-S proteins in sensing and regulatory functions
8. Sequence and molecular analysis of the nifL gene of Azotobacter vinelandii
9. Transcriptional activation of the Klebsiella pneumoniae nitrogenase promoter may involve DNA loop formation
10. Mechanism of molybdenum nitrogenase
11. 2-fixing enzyme systeme in Clostridium pasteurianum
12. Biochemical genetics of nitrogenase
13. The oxygen-responsive NifL-NifA complex: A novel two-component regulatory system controlling nitrogenase synthesis in gamma-proteobacteria
14. The function of isolated domains and chimaeric proteins constructed from the transcriptional activators NifA and NtrC of Klebsiella pneumoniae
15. Sequence of nifL from Klebsiella pneumoniae: Mode of action and relationship to two families of regulatory proteins
16. Transcriptional activation of the nitrogenase promoter in vitro: Adenosine nucleotides are required for inhibition of NifA activity by NifL
17. Cloning and characterization of nifLA regulatory mutations from Klebsiella pneumoniae
18. Genetic regulation of nitrogen fixation in rhizobia
19. Environmental regulation of rhizobial symbiotic nitrogen fixation genes
20. Mechanism of translational coupling in the nifLA operon of Klebsiella pneumoniae
21. Cloning, sequencing and characterization of Fnr from Klebsiella pneumoniae
22. Fnr is required for NifL-dependent oxygen control of nif gene expression in Klebsiella pneumoniae
23. Regulation of biological nitrogen fixation
24. NtrC is required for control of Klebsiella pneumoniae NifL activity
25. Physiological role for the GlnK protein of enteric bacteria: Relief of NifL inhibition under nitrogen-limiting conditions
26. Role of metal ions in negative regulation of nitrogen fixation by the nifL gene produkt from Klebsiella pneumoniae
27. Redox regulation of enteric nif expression is independent of the fnr gene product
28. Azotobacter vinelandii NifL is a flavoprotein that modulates transcriptional activation of nitrogen-fixation genes via a redox-sensetive switch
29. Nitrogen fixation gene (nifL) involved in oxygen regulation of nitrogenase synthesis in Klebsiella pneumoniae
30. The integration host factor stimulates interaction of RNA polymerase with NIFA, the transcriptional activator for nitrogen fixation operons
31. Structural basis of biological nitrogen fixation
32. Salmonella typhimurium apparently perceives external nitrogen limitation as internal glutamine limitation
33. The signal transduction protein GlnK is required for NifL-dependent nitrogen control of nif gene expression in Klebsiella pneumoniae
34. 2: [4Fe-4S] to [2Fe-2S] conversion with loss of biological activity
35. Oxygen sensing by the global regulator, FNR: The role of the iron-sulfur cluster
36. NifL of Klebsiella pneumoniae: Redox characterization in relation to the nitrogen source
37. Membrane association of Klebsiella pneumoniae NifL is affected by molecular oxygen and combined nitrogen
38. The inhibitory form of NifL from Klebsiella pneumoniae exhibits ATPase activity only when synthesized under nitrogen sufficiency
39. Activity of purified NIFA, a transcriptional activator of nitrogen fixation genes
40. In vitro activity of NifL, a signal transduction protein for biological nitrogen fixation
41. Genetic analysis of nif regulatory genes by utilizing the yeast two-hybrid system detected formation of a NifL-NifA complex that is implicated in regulated expression of nif genes
42. Signal transduction to the Azotobacter vinelandii NIFL-NIFA regulatory system is influenced directly by interaction with 2-oxoglutarate and the PII regulatory protein
43. Nitrogen fixation by methanogenic bacteria
44. Electron donation to the flavoprotein NifL, a redox-rensing transcriptional regulator
45. Characterization of the glnK-amtB operon of Azotobacter vinelandii
46. Nitrogen control in bacteria
47. Repressor properties of the nifL gene product in Klebsiella pneumoniae
48. Isolation and properties of the complex between the enhancer binding protein NifA and the sensor NifL
49. Protein-protein interactions in the complex between the enhancer binding protein NifA and the sensor NifL from Azotobacter vinelandii
50. In-trans regulation of the N-truncated-NIFA protein of Herbaspirillum seropedicae by the N-terminal domain
51. Expression and functional analysis of an N-truncated NifA protein of Herbaspirillum seropedica
52. The sigma 54 bacterial enhancer-binding protein family: Mechanism of action and phylogenetic relationship of their functional domains
53. NifA-dependent in vivo protection demonstrates that the upstream activator sequence of nif promoters is a protein binding site
54. 54 with the Klebsiella pneumoniae and Rhizobium meliloti nifH promoters
55. The C-terminal domain of NifL is sufficient to inhibit NifA activity
56. PII signal transduction proteins
57. Respiratory protection of nitrogenase in Azotobacter species: Is a widely held hypothesis unequivocally supported by experimental evidence?
58. Oxygen reactions with bacterial oxidases and globins: Binding, reduction and regulation
59. Structural bioenergetics and energy transduction mechanisms
60. Azoarcus gen. nov., nitrogen-fixing proteobacteria associated withroots of kallar grass (Leptochloa fusca (L.) Kunth), and description of two species, Azoarcus indigens sp. nov. and Azoarcus communis sp. nov.
61. Role of Escherichia coli nitrogen regulatory genes in the nitrogen response of the Azotobacter vinelandii NifL-NifA complex
62. Regulation of Azotobacter vinelandii NifA activity by NifL: Role of PII-like proteins in nitrogen sensing
63. Iron is required to relieve inhibitory effects of NifL on transcriptional activation by NifA in Klebsiella pneumoniae
64. NifL of Klebsiella pneumoniae carries an N-terminally bound FAD cofactor, which is not directly required for the inhibitory function of NifL
65. Internal glutamine and glutamate pools in Klebsiella pneumoniae grown under different conditions of nitrogen availability
66. The redox and fixed nitrogen-responsive regulatory protein NifL from Azotobacter vinelandii comprises discrete flavin and nucleotide-binding domains
67. Control of Herbaspirillum seropedicae NifA activity by ammonium ions and oxygen
68. Azospirillum, a free-living nitrogen-fixing bacterium closely associated with grasses: Genetic, biochemical and ecological aspects
69. Aerotaxis and other energy-sensing behavior in bacteria
70. Regulation of nitrogen metabolism in Azotobacter vinelandii: Isolation of ntr and glnA genes and construction of ntr mutants
71. In vivo energetics and control of nitrogen fixation: Changes in the adenylate energy charge and adenosine 5′-diphosphate/adenosine 5′-triphosphate ratio of cells during growth on dinitrogen versus growth on ammonia
72. Redundancy of the conserved his residue in Azotobacter vinelandii NifL, a histidine protein kinase homologue which regulates transcription of nitrogen fixation genes
73. NifL, an antagonistic regulator of NifA interacting with NifA
74. Phylogenetic classification of nitrogen fixing organisms
75. PAS domain S-boxes in Archaea, Bacteria and sensors for oxygen and redox