α1-Adrenoceptor-induced contractility in rat aorta is mediated by the α1D subtype

European Journal of Pharmacology

Volumn 297, Issue 3, 1996, Pages 241-248

  Buckner, Steven A ^a   Oheim, K W ^a   Morse, P A ^a   Knepper, S M ^a   Hancock, A A ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Aorta, rat; Contractility; Radioligand binding; 1D Adrenoceptor

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; 2 [2 (4 HYDROXYPHENYL)ETHYLAMINOMETHYL]TETRALONE; 2 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 4,4 DIMETHYL 1,3(2H,4H) ISOQUINOLINEDIONE; 2 [[2 (2,6 DIMETHOXYPHENOXY)ETHYL]AMINOMETHYL] 1,4 BENZODIOXAN; 5 METHYLURAPIDIL; ADRENALIN; ALFUZOSIN; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1B ADRENERGIC RECEPTOR; ALPHA 1D ADRENERGIC RECEPTOR; CHLOROETHYLCLONIDINE; CIRAZOLINE; DOXAZOSIN; INDORAMIN; METHOXAMINE; N [5 (4,5 DIHYDRO 1H IMIDAZOL 2 YL) 5,6,7,8 TETRAHYDRO 2 HYDROXY 1 NAPHTHYL]METHANESULFONAMIDE; NORADRENALIN; OXYMETAZOLINE; PHENTOLAMINE; PHENYLEPHRINE; PRAZOSIN; PROPRANOLOL; RADIOLIGAND; RECEPTOR SUBTYPE; TAMSULOSIN; TERAZOSIN; UNCLASSIFIED DRUG;

ANIMAL; AORTA; ARTICLE; CLASSIFICATION; DOG; DRUG EFFECT; DRUG POTENTIATION; IN VITRO STUDY; MALE; MUSCLE ISOMETRIC CONTRACTION; PHYSIOLOGY; RADIOASSAY; RAT; SPRAGUE DAWLEY RAT; ANIMAL TISSUE; BINDING AFFINITY; CATTLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; HAMSTER; HUMAN; LIGAND BINDING; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROSTATE; SMOOTH MUSCLE CONTRACTILITY; SPLEEN; SUBMANDIBULAR GLAND; THORACIC AORTA; VAS DEFERENS;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; AORTA; DOGS; ISOMETRIC CONTRACTION; MALE; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-1;

EID: 0029665772     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(95)00755-5     Document Type: Article

References (26)

1. 1-adrenoceptor mediating contractions of the rat aorta, vas deferens, and spleen, Br. J. Pharmacol. 109, 80.
2. Arunlakshana, O. and H.O. Schild, 1959, Some quantitative uses of drug antagonists, Br. J. Pharmacol. 14, 48.
3. Auch-Schwelk, W. and P.M. Vanhoutte, 1991, Calcium antagonists inhibit contractions to norepinephrine in the rat aorta in the absence but not in the presence of the endothelium, Gen. Pharmacol. 22, 595.
4. Bylund, D. B., D.C. Eikenberg, J.P. Hieble, S.Z. Langer, R.J. Lefkowitz, K.P. Minneman, P.B. Molinoff, R.R. Ruffolo Jr. and U. Trendelenburg IV, 1994, International Union of Pharmacology nomenclature of adrenoceptors. Pharmacol. Rev. 46, 121.
5. DeLean, A., P.J. Munson and D. Rodbard, 1980, Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves, Am. J. Physiol. 235, E97.
6. 1 Adrenoceptor classification: sharpening Occam's razor, Trends Pharmacol. Sci. 15, 167.
7. 2 antagonist, Drug Dev. Res. 28, 56.
8. 1-adrenoceptors, Eur. J. Pharmacol. 272, R5.
9. 3H-prazosin to rat brain alpha-adrenergic receptors, Eur. J. Pharmacol. 55, 323.
10. 1-adrenoceptor, Eur. J. Pharmacol. 151, 333.
11. 1D-adrenoceptor) to the contraction of vascular smooth muscle, FASEB J. 9, 239.
12. 1-adrenoceptors in rat blood vessels, Eur. J. Pharmacol. 190, 97.
13. Hancock, A.A., J.J. Kyncl, Y.C. Martin and J.F. DeBernardis, 1988, Differentiation of alpha-adrenergic receptors using pharmacological evaluation and molecular modeling of selective adrenergic agents, J. Rec. Res. 8, 23.
14. 1 adrenoceptor antagonists on prostatic pressure and blood pressure in the anesthetized dog, Urology 44, 52.
15. 1D-adrenoceptor mediating the contractile response of rat aorta to noradrenaline, Br. J. Pharmacol. 115, 981.
16. 1A receptor subtype, J. Pharmacol. Exp. Ther. 274, 97.
17. 1D-adrenoceptor antagonist, isolated from Fissistigma glaucescens, Br. J. Pharmacol. 112, 1174.
18. 1A-subtype in rat submaxillary gland, Br. J. Pharmacol. 98, 883.
19. +2, Pharmacol. Rev. 40, 87.
20. Muramatsu, I., S. Kigoshi and T. Ohmura, 1991, Subtypes of α1-adrenoceptors involved in noradrenaline induced contractions of rat thoracic aorta and dog carotid artery, Jpn. J. Pharmacol. 57, 535.
21. 1D-adrenergic receptor cDNA, Mol. Pharmacol. 40, 876.
22. Piascik, M.T., M.S. Sparks, T.A. Pruitt and E.E. Soltis, 1991, Evidence for a complex interaction between the subtypes of the α1-adrenoceptor, Eur. J. Pharmacol. 199, 279.
23. 1D subtype, Can. J. Physiol. Pharmacol. 72, Suppl. 1, 323.
24. Snedecor, G.W. and W.G. Cochran, 1980, Statistical Methods, 7th edn. (Iowa State University Press, Ames, Iowa).
25. 1B-adrenoceptor subtype, Br. J. Pharmacol. 114, 745.
26. Tian, W.N., S. Gupta and R.C. Deth, 1990, Species differences in chloroethylclonidine antagonism at vascular α-1 adrenergic receptors, J. Pharmacol. Exp. Ther. 253, 877.