Methotrexate selection of long-term culture initiating cells following transduction of CD34+ cells with a retrovirus containing a mutated human dihydrofolate reductase gene

Cancer Gene Therapy

Volumn 9, Issue 3, 2002, Pages 308-320

  Takebe, Naoko ^a   Xu, Li Cheng ^a   MacKenzie, Karen L ^a   Bertino, Joseph R ^a   Moore, Malcolm As ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Double mutant dihydrofolate reductase; Enhanced green fluorescent protein; Fusion protein; Gene therapy; Methotrexate; Stem cell selection

Indexed keywords

CD34 ANTIGEN; DIHYDROFOLATE REDUCTASE; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; METHOTREXATE; VIRUS VECTOR;

ARTICLE; CELL CULTURE; CELL POPULATION; CELL SELECTION; COLONY FORMING UNIT GM; FLOW CYTOMETRY; FUSION GENE; GENE THERAPY; GENE TRANSFER; GENETIC TRANSDUCTION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RETROVIRUS; STEM CELL TRANSPLANTATION; STROMA CELL;

UNIDENTIFIED RETROVIRUS;

EID: 0036195837     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700443     Document Type: Article

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