Comparison of methotrexate resistance conferred by a mutated dihydrofolate reductase (DHFR) cDNA in two different retroviral vectors

Cancer Gene Therapy

Volumn 7, Issue 6, 2000, Pages 910-919

  Takebe, Naoko ^a   Nakahara, Saori ^b   Zhao, Shi Cheng ^a   Adhikari, Debasis ^a   Ural, Ali U ^c   Iwamoto, Marian ^a   Banerjee, Debabrata ^a   Bertino, Joseph R ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

^c GULHANE SCHOOL OF MEDICINE   (Turkey)

Author keywords

Gene transfer efficiency; Mutated dihydrofolate reductase cDNA; N2 based double copy vector; SFG based dicistronic vector

Indexed keywords

COMPLEMENTARY DNA; DIHYDROFOLATE REDUCTASE; METHOTREXATE; VIRUS VECTOR;

ANIMAL CELL; ARTICLE; CANCER RESISTANCE; CONTROLLED STUDY; DOSE RESPONSE; GENE THERAPY; GENE TRANSFER; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL;

ANIMALIA;

EID: 0033920754     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700199     Document Type: Article

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