Uncertainty in the analysis of tracer kinetics using dynamic contrast-enhanced T1-weighted MRI

Magnetic Resonance in Medicine

Volumn 47, Issue 3, 2002, Pages 601-606

  Buckley, David L ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Blood volume; Capillary permeability; Carcinoma; Gadolinium; Kinetic modeling; Perfusion

Indexed keywords

BLOOD; BLOOD VESSELS; GADOLINIUM; HEMODYNAMICS; KINETICS; PARAMETER ESTIMATION; TRACERS; UNCERTAINTY ANALYSIS;

BLOOD VOLUMES; CARCINOMA; CONCENTRATION-TIME; DYNAMIC CONTRAST ENHANCED; KINETIC MODELING; PARAMETER ESTIMATE; PERFUSION; PHYSIOLOGICAL PARAMETERS;

PHYSIOLOGICAL MODELS;

GADOLINIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VOLUME; CALCULATION; CAPILLARY PERMEABILITY; CONCENTRATION RESPONSE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DRUG BLOOD LEVEL; DYNAMICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PERFUSION; SIMULATION;

EID: 0036191012     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.10080     Document Type: Article

References (24)

1. Pharmacokinetic analysis of neoplasms using contrast-enhanced dynamic magnetic resonance imaging
2. Capillary transfer constant of Gd-DTPA in the myocardium at rest and during vasodilation assessed by MRI
3. Microvessel density in invasive breast cancer assessed by dynamic Gd-DTPA enhanced MRI
4. Noninvasive assessment of the functional neovasculature in 9L-glioma growing in rat brain by dynamic H-1 magnetic resonance imaging of gadolinium uptake
5. Tracer-kinetic models for measuring cerebral blood flow using externally detected radiotracers
6. Temporal sampling requirements for the tracer kinetics modeling of breast disease
7. Delay and dispersion effects in dynamic susceptibility contrast MRI: Simulations using singular value decomposition
8. Modeling cerebral blood flow and flow heterogeneity from magnetic resonance residue data
9. Measurement of the blood-brain barrier permeability and leakage space using dynamic MR imaging. I. Fundamental concepts
10. Pitfalls in the measurement of tissue permeability over short time-scales using a low temporal resolution blood input function
11. Measurement of the arterial concentration of Gd-DTPA using MRI: A step toward quantitative perfusion imaging
12. Improved 3D quantitative mapping of blood volume and endothelial permeability in brain tumors
13. Modeling in the analysis of solute and water exchange in the microvasculature
14. Modeling regional myocardial flows from residue functions of an intravascular indicator
15. Determinants of tumor blood flow: A review
16. Modeling tracer kinetics in dynamic Gd-DTPA MR imaging
17. The theory and applications of the exchange of inert gas at the lungs and tissues
18. Quantitation of blood-brain barrier defect by magnetic resonance imaging and gadolinium-DTPA in patients with multiple sclerosis and brain tumors
19. 1-weighted MRI of a diffusable tracer: Standardized quantities and symbols
20. An adiabatic approximation to the tissue homogeneity model for water exchange in the brain. I. Theoretical derivation
21. Simultaneous MRI measurement of blood flow, blood volume, and capillary permeability in mammary tumors using two different contrast agents
22. Direct comparison of an intravascular and an extracellular contrast agent for quantification of myocardial perfusion
23. Dynamic MR imaging of the breast combined with analysis of contrast agent kinetics in the differentiation of primary breast tumours