Noninvasive assessment of the functional neovasculature in 9L-glioma growing in rat brain by dynamic 1H magnetic resonance imaging of gadolinium uptake

Journal of Cerebral Blood Flow and Metabolism

Volumn 20, Issue 5, 2000, Pages 861-870

  Van Der Sanden, Boudewijn P J ^a,c   Rozijn, Tom H ^b   Rijken, Paul F J W ^a   Peters, Hans P W ^a   Heerschap, Arend ^a   Van Der Kogel, Albert J ^a   Bovée, Wim M M J ^b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Fluorescence microscopy; Gadolinium uptake rates 9L Glioma; Magnetic resonance imaging; Perfused vascular architecture

Indexed keywords

ANIMAL CELL; ARTICLE; BRAIN BLOOD FLOW; GLIOMA; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; TUMOR BLOOD FLOW;

EID: 0034025631     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-200005000-00013     Document Type: Article

References (8)

1. Adair TH, Wellis ML, Hang J, Montani J-P (1994) Stereological method for the estimating length density of the arterial vascular system. Am J Physiol 266:H1424-H1438
2. Artemov D, Bhujwalla ZM (1997) 3-Dimensional MRI quantitation of tumor vascular volume and permeability [abstract]. In: Proceed-ings of the International Society for Magnetic Resonance Medicine, 5th Meeting, Vancouver, Canada, 1997, p 491
3. Barentsz JO, Berger Hartog O, Witjes JA, et al (1998) Evaluation of chemotherapy in advanced urinary bladder cancer with fast dynamic contrast-enhanced MR imaging. Radiology 207:791797
4. Tofts PS, Kermode AG (1991) Measurement of the blood-brain barrier permeability and leakage space using dynamic MR imaging. 1. Fundamental concepts. Magn Res Med 17:357-367
5. 31P-magnetic resonance spectroscopy and morphometric analysis of the perfused vascular architecture of human glioma xenografts in nude mice. Br J Cancer 75:1432-1438
6. 99mTc(DTPA in rats. Magn Res Im 8: 567-575
7. Weidner N, Folkman J (1999) Tumoral vascularity as a prognostic factor in cancer. In: Important advances in oncology (Devita VT, Hellman S, Rosenberg SA, eds), Philadelphia: Lippincott-Raven, pp 167-190
8. Weidner N, Semple JP, Welch WR, Folkman J (1991) Tumor angiogenesis and metastasis correlation in invasive breast carcinoma. N Engl J Med 324:1-8