Cysteine and serine protease inhibitors block intracellular development and disrupt the secretory pathway of Toxoplasma gondii

Microbes and Infection

Volumn 4, Issue 2, 2002, Pages 119-132

  Shaw, Michael K ^b   Roos, David S ^a   Tilney, Lewis G ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF READING   (United Kingdom)

Author keywords

Daughter cell budding; Protease inhibitors; Secretory pathway; Toxoplasma; Ultrastructure

Indexed keywords

3,4 DICHLOROISOCOUMARIN; ALOXISTATIN ACID; ARPHAMENINE A; CALPASTATIN; CATHEPSIN INHIBITOR III; CYSTEINE PROTEINASE INHIBITOR; LEUPEPTIN; PEPSTATIN; SERINE PROTEINASE INHIBITOR; SUBTILISIN INHIBITOR III; TOSYLLYSYL CHLOROMETHYL KETONE; TOSYLPHENYLALANYL CHLOROMETHYL KETONE; UNCLASSIFIED DRUG;

ARTICLE; CELL NUCLEUS MEMBRANE; CELL ULTRASTRUCTURE; CELL VACUOLE; CONTROLLED STUDY; DRUG EFFECT; ENDOPLASMIC RETICULUM; GOLGI COMPLEX; GROWTH INHIBITION; HOST CELL; HUMAN; HUMAN CELL; INTRACELLULAR RECORDING; LYSOSOME; NONHUMAN; PARASITE DEVELOPMENT; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN MODIFICATION; PROTEIN SECRETION; SKIN FIBROBLAST; TOXOPLASMA GONDII;

ANIMALS; COCCIDIOSTATS; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DRUG EVALUATION, PRECLINICAL; FIBROBLASTS; HUMANS; INTRACELLULAR MEMBRANES; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; TOXOPLASMA;

TOXOPLASMA; TOXOPLASMA GONDII;

EID: 0036189061     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1286-4579(01)01520-9     Document Type: Article

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