The Toxoplasma adhesive protein MIC2 is proteolytically processed at multiple sites by two parasite-derived proteases

Journal of Biological Chemistry

Volumn 275, Issue 19, 2000, Pages 14346-14353

  Carruthers, Vern B ^a,b   Sherman, Gale D ^b   Sibley, L David ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE; PROTOZOAL PROTEIN;

ARTICLE; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN MODIFICATION; PROTEIN PROCESSING; PROTEIN TRANSPORT; TOXOPLASMA GONDII;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; CYTOCHALASIN D; DNA PRIMERS; HYDROLYSIS; INTEGRINS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTOZOAN PROTEINS; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; TOXOPLASMA;

EID: 0034640516     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.19.14346     Document Type: Article

References (29)

1. Russell, D. G., and Wilhelm, H. (1986) J. Immunol. 136, 2613-2620
2. Caler, E. V., Vaena de Avalos, S., Haynes, P. A., Andrews, N. W., and Burleigh, B. A. (1998) EMBO J. 17, 4975-4986
3. Banyal, H. S., Misra, G. C., Gupta, C. M., and Dutta, G. P. (1981) J. Parasitol. 67, 623-626
4. Dejkriengkraikhul, P., and Wilairat, P. (1983) Z. Parasitenkd. 69, 313-317
5. Dluzewski, A. R., Rangachari, K., Wilson, R. J. M., and Gratzer, W. B. (1986) Exp. Parasitol. 62, 416-422
6. Conseil, V., Soete, M., and Dubremetz, J.-F. (1999) Antimicrob. Agents Chemother. 43, 1358-1361
7. Hakansson, S., Morisaki, H., Heuser, J., and Sibley, L. D. (1999) Mol. Biol. Cell 10, 3539-3547
8. Aikawa, M., Komata, Y., Asai, T., and Midorikawa, O. (1977) Am. J. Pathol. 87, 285-296
9. Nichols, B. A., and O'Connor, G. R. (1981) Lab. Invest. 44, 324-335
10. Dobrowolski, J. M., and Sibley, L. D. (1996) Cell 84, 933-939
11. Dobrowolski, J. M., Carruthers, V. B., and Sibley, L. D. (1997) Mol. Microbiol. 26, 163-173
12. Ortega-Barria, E., and Boothroyd, J. C. (1999) J. Biol. Chem. 274, 1267-1276
13. Fourmaux, M. N., Achbarou, A., Mercereau-Puijalon, O., Biderre, C., Eriche, I., Loyens, A., Odberg-Ferragut, C., Camus, D., and Dubremetz, J.-F. (1996) Mol. Biochem. Parasitol. 83, 201-210
14. Wan, K.-L., Carruthers, V. B., Sibley, L. D., and Ajioka, J. W. (1997) Mol. Biochem. Parasitol. 84, 203-214
15. Carruthers, V. B., Giddings, O. K., and Sibley, L. D. (2000) Cell. Microbiol., in press
16. Carruthers, V. B., and Sibley, L. D. (1997) Eur. J. Cell Biol. 73, 114-123
17. Sultan, A. A., Thathy, V., Frevert, U., Robson, K. J., Crisanti, A., Nussenzweig, V., Nussenzweig, R. S., and Menard, R. (1997) Cell 90, 511-522
18. Carruthers, V. B., and Sibley, L. D. (1999) Mol. Microbiol. 31, 421-428
19. Dubremetz, J.-F., and Dissous, C. (1980) Mol. Biochem. Parasitol. 1, 279-289
20. Kawazoe, U., Tomley, F. M., and Frazier, J. A. (1992) Parasitology 104, 1-9
21. Carruthers, V. B., Moreno, S. N. J., and Sibley, L. D. (1999) Biochem. J. 342, 379-386
22. Wan, K.-L., Blackwell, J. M., and Ajioka, J. W. (1996) Mol. Biochem. Parasitol. 75, 179-186
23. Dubremetz, J.-F. (1998) Trends Microbiol. 6, 27-30
24. Johnson, A. M., and Illana, S. (1991) Gene (Amst.) 99, 127-132
25. Kumar, A., Shafiq, S., Wadgaonkar, R., and Stracher, A. (1992) Cell. Mol. Biol. 38, 477-483
26. Achbarou, A., Mercereau-Puijalon, O., Autherman, J. M., Fortier, B., Camus, D., and Dubremetz, J.-F. (1991) Mol. Biochem. Parasitol. 47, 223-234
27. Adams, J. H., Hudson, D. E., Torii, M., Ward, G. E., Wellems, T. E., Aikawa, M., and Miller, L. H. (1990) Cell 63, 141-153
28. Ogun, S. A., and Holder, A. A. (1996) Mol. Biochem. Parasitol. 76, 321-324
29. Blackman, M. J., and Holder, A. A. (1992) Mol. Biochem. Parasitol. 50, 307-315