Identification of a multicopy chromatin boundary element at the borders of silenced chromosomal domains

Chromosoma

Volumn 110, Issue 8, 2002, Pages 519-531

  Cuvier, Olivier ^a,c,d   Hart, Craig M ^a,c,d   Käs, Emmanuel ^b,c,d   Laemmli, Ulrich K ^a,c,d  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b Université Paul Sabatier   (France)

^c LOUISIANA STATE UNIVERSITY   (United States)

^d Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOUNDARY ELEMENT ASSOCIATED FACTOR; CHROMOSOME PROTEIN; DNA BINDING PROTEIN; NUCLEASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING KINETICS; CHROMATIN STRUCTURE; CHROMOSOME ANALYSIS; CHROMOSOME IDENTIFICATION; DNA SEQUENCE; DROSOPHILA MELANOGASTER; EUCHROMATIN; HETEROCHROMATIN; HUMAN; NONHUMAN; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; TRANSGENIC ANIMAL; YEAST;

ANIMALIA; DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0036189045     PISSN: 00095915     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00412-001-0181-1     Document Type: Article

References (64)

1. Isolation and sequencing of cDNA clones encoding Drosophila chromosomal protein D1. A repeating motif in proteins which recognize at DNA
2. Induction of early transcription in one-cell mouse embryos by microinjection of the nonhistone chromosomal protein HMG-I
3. Stopped at the border: Boundaries and insulators
4. The protein CTCF is required for the enhancer blocking activity of vertebrate insulators
5. UASrpg can function as a heterochromatin boundary element in yeast
6. Modulation of enhancer-promoter interactions by insulators in the Drosophila embryo
7. Effects of cis arrangement of chromatin insulators on enhancer-blocking activity
8. A 5′ element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila
9. Characterization of the chicken beta-globin insulator
10. Identification of a class of chromatin boundary elements
11. Mapping three-dimensional chromosome architecture in situ
12. The boundaries of the silenced HMR domain in Saccharomyces cerevisiae
13. Looping, linking, and chromatin activity: New insights into beta-globin locus regulation
14. Cohabitation of insulators and silencing elements in yeast subtelomeric regions
15. Regena (Rga), a Drosophila homolog of the global negative transcriptional regulator CDC36 (NOT2) from yeast, modifies gene expression and suppresses position effect variegation
16. The Zw5 protein, a component of the scs chromatin domain boundary, is able to block enhancer-promoter interaction
17. DNA position-specific repression of transcription by a Drosophila zinc finger protein
18. In vivo analysis of scaffold-associated regions in Drosophila: A synthetic high-affinity SAR binding protein suppresses position effect variegation
19. Intergenic transcription and developmental remodeling of chromatin subdomains in the human beta-globin locus
20. A new homeotic mutation in the Drosophila bithorax complex removes a boundary separating two domains of regulation
21. A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation
22. Facilitation of chromatin dynamics by SARs
23. The scs' boundary element: Characterization of boundary element-associated factors
24. Evidence for an antagonistic relationship between the boundary element-associated factor BEAF and the transcription factor DREF
25. Repression of hsp70 heat shock gene transcription by the suppressor of hairy-wing protein of Drosophila melanogaster
26. Position-independent transgene expression mediated by BEs from the apolipoprotein B chromatin domain
27. Mcp and Fab-7: Molecular analysis of putative boundaries of cis-regulatory domains in the bithorax complex of Drosophila melanogaster
28. Reduced DNA polytenization of a minichromosome region undergoing position-effect variegation in Drosophila
29. In vivo topoisomerase II cleavage of the Drosophila histone and satellite III repeats: DNA sequence and structural characteristics
30. A position-effect assay for boundaries of higher order chromosomal domains
31. A group of scs elements function as domain boundaries in an enhancer-blocking assay
32. CTCF, a conserved nuclear factor required for optimal transcriptional activity of the chicken c-myc gene, is an 11-Zn-finger protein differentially expressed in multiple forms
33. D1 protein of Drosophila melanogaster. Purification and AT-DNA binding properties
34. Protein D1 preferentially binds A + T-rich DNA in vitro and is a component of Drosophila melanogaster nucleosomes containing A + T-rich satellite DNA
35. Polycomb group repression is blocked by the Drosophila suppressor of Hairy-wing [su(Hw)] insulator
36. Matrix-attachment regions can impart position-independent regulation of a tissue-specific gene in transgenic mice
37. Organization of the higher-order chromatin loop: Specific DNA attachment sites on nuclear scaffold
38. Loss of insulator activity by paired Su(Hw) chromatin insulators
39. A nuclear matrix/scaffold attachment region co-localizes with the gypsy retrotransposon insulator sequence
40. A simple method to renature DNA-binding proteins separated by SDS-polyacrylamide gel electrophoresis
41. SARs stimulate but do not confer position independent gene expression
42. Dosage compensation of the Drosophila white gene requires both the X chromosome environment and multiple intragenic elements
43. Site-independent expression of the chicken beta-globin gene in transgenic mice
44. The repeat organizer, a specialized insulator element within the intergenic spacer of the Xenopus rRNA genes
45. Isolation, properties and cellular distribution of D1, a chromosomal protein of Drosophila
46. Systematic gain-of-function genetics in Drosophila
47. The su(Hw) protein insulates expression of the Drosophila melanogaster white gene from chromosomal position-effects
48. Enhancer blocking by the Drosophila gypsy insulator depends upon insulator and enhancer strength
49. The Saccharomyces cerevisiae Start-specific transcription factor Swi4 interacts through the ankyrin repeats with the mitotic Clb2/Cdc28 kinase and through its conserved carboxy terminus with Swi6
50. Chromatin insulator elements block the silencing of a target gene by the Drosophila polycomb response element (PRE) but allow trans interactions between PREs on different chromosomes
51. SARs are cis DNA elements of chromosome dynamics: Synthesis of a SAR repressor protein
52. Putting boundaries on silence
53. The 87A7 chromomere. Identification of novel chromatin structures flanking the heat shock locus that may define the boundaries of higher order domains
54. Transcriptional repression mediated by polycomb group proteins and other chromatin-associated repressors is selectively blocked by insulators
55. Sequences required for enhancer blocking activity of scs are located within two nuclease-hypersensitive regions
56. Genetic and molecular analysis of chromatin domains
57. The zinc finger protein CTCF binds to the APBbeta domain of the amyloid beta-protein precursor promoter. Evidence for a role in transcriptional activation
58. The chicken beta-globin 5′HS4 boundary element blocks enhancer-mediated suppression of silencing
59. The 5′ ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I
60. Separate cis-regulatory sequences control expression of serendipity beta and janus A, two immediately adjacent Drosophila genes
61. SAR-dependent mobilization of histone H1 by HMG-I/Y in vitro: HMG-I/Y is enriched in H1-depleted chromatin
62. Visualization of chromosomal domains with boundary element-associated factor BEAF-32
63. Enhancer-blocking activity within the DNase I hypersensitive site 2 to 6 region between the TCR alpha and Dad1 genes