Polycomb group repression is blocked by the Drosophila suppressor of Hairy-wing [SU(HW)] insulator

Genetics

Volumn 148, Issue 1, 1998, Pages 331-339

  Mallin, Daniel R ^a   Myung, Jane S ^a   Patton, J Scott ^a   Geyer, Pamela K ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; REPRESSOR PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENHANCER REGION; EUCHROMATIN; EYE COLOR; FEMALE; GENE EXPRESSION; GENE REPRESSION; GENOME; MALE; NONHUMAN; POSITION EFFECT; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; SUPPRESSOR GENE; TRANSGENE; TRANSPOSON;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; DNA TRANSPOSABLE ELEMENTS; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; EYE PROTEINS; GENES, INSECT; GENES, SUPPRESSOR; INSECT PROTEINS; NUCLEAR PROTEINS; REPRESSOR PROTEINS; SUPPRESSION, GENETIC;

EID: 0031931429     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. BENDER, W., M. AKAM, F. KARCH, P. BEACHY, M. PEIFER et al., 1983 Molecular genetics of the bithorax complex in Drosophila melanogaster. Science 221: 23-29.
2. CAI, H., and M. LEVINE, 1995 Modulation of enhancer-promoter interactions by insulators in the Drosophila embryo. Nature. 376: 533-536.
3. CHAN, C.-S., L. RASTELLI and V. PIRROTTA, 1994 A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression. EMBO 13: 3822-3831.
4. CHIANG, A., M. O'CONNOR, R. PARO, J. SIMON and W. BENDER, 1995 Discrete Polycomb binding sites in each parasegmental domain of the bithorax complex. Development 121: 1681-1689.
5. CSINK, A. K., and S. HENIKOFF, 1996 Genetic modification of heterochromatic association and nuclear organization in Drosophila. Nature 381: 529-531.
6. DECAMILLIS, M., N. CHENG, D. PIERRE and H. W. BROCK, 1992 The polyhomeotic gene of Drosophila encodes a chromatin protein that shares polytene chromosome-binding sites with Polycomb. Genes & Dev. 6: 223-232.
7. DERNBURG, A. F., K. W. BROMAN, J. C. FUNG, W. F. MARSHALL, J. PHILIPS et al., 1996 Perturbation of nuclear architecture by long-distance chromosome interactions. Cell 85: 745-759.
8. DORSETT, D., 1993 Distance-independent inactivation of an enhancer by the suppressor of Hairy-wing DNA-binding protein of Drosophila. Genetics 134: 1135-1144.
9. FAUVARQUE, M.-O., and J.-M. DURA, 1993 polyhomeotic regulatory sequences induce developmental regulator-dependent variegation and targeted P-element insertions in Drosophila. Genes & Dev. 7: 1508-1520.
10. FLAVELL, A. J., L. S. ALPHEY, S. J. ROSS and A. J. LEIGH-BROWN, 1990 Complete reversions of a Gypsy retrotransposon-induced cut locus mutation in Drosophila melanogaster involving jockey transposon insertions and flanking Gypsy sequence deletions. Mol. & Gen. Genet. 220: 181.
11. GEYER, P. K., and V. G. CORCES, 1987 Separate regulatory elements are responsible for the complex pattern of tissue-specific and developmental transcription of the yellow locus in Drosophila melanogaster. Genes & Dev. 1: 996-1004.
12. GEYER, P. K., and V. G. CORCES, 1992 DNA position-specific repression of transcription by a Drosophila zinc finger protein. Genes & Dev. 6: 1865-1873.
13. GEYER, P. K., C. SPANA and V. G. CORCES, 1986 On the molecular mechanism of gypsy-induced mutations at the yellow locus of Drosophila melanogaster. EMBO J. 5: 2657-2662.
14. GEYER, P. K., M. M. GREEN and V. G. CORCES, 1988 Reversion of a gypsy-induced mutation at the yellow (y) locus of Drosophila melanogaster is associated with the insertion of a newly denned transposable element. Proc. Natl. Acad. Sci. USA 85: 3938-3942.
15. GINDHART, J. G., and T. C. KAUFMAN, 1995 Identification of Polycomb and Trithorax group responsive elements in the regulatory region of the Drosophila homeotic gene Sex combs reduced. Genetics 139: 797-814.
16. HAGSTROM, K., M. MULLER and P. SCHEDL, 1996 Fab-7 functions as a chromatin domain boundary to ensure proper segment specification by the Drosophila bithorax complex. Genes & Dev. 10: 3202-3215
17. HARRISON, D. A., M. A. MORTIN and V. G. CORCES, 1992 The RNA polymerase II 15-kilodalton subunit is essential for viability in Drosophila melanogaster. Mol. Cell. Biol. 12: 928-935.
18. HARRISON, D. A., D. A. GDULA, R. S. COYNE and V. G. CORCES, 1993 A leucine zipper domain of the suppressor of Hairy-wing protein mediates its repressive effect on enhancer function. Genes & Dev. 7: 1966-1978.
19. HOLDRIDGE, C., and D. DORSETT, 1991 Repression of hsp70 heat shock gene transcription by the suppressor of Hairy-wing protein of Drosophila melanogaster. Mol. Cell. Biol. 11: 1894-1900.
20. JACK, J., D. DORSETT, Y. DELOTTO and S. LIU, 1991 Expression of the cut locus in the Drosophila wing margin is required for cell type specification and is regulated by a distal enhancer. Development 113: 735-748.
21. KARESS, R. E., and G. M. RUBIN, 1984 Analysis of P transposable element functions in Drosophila. Cell 38: 135-146.
22. KASSIS, J. A., 1994 Unusual properties of regulatory DNA from the Drosophila engrailed gene: three "pairing-sensitive" sites within a 1.6-kb region. Genetics 136: 1025-1038.
23. KENNISON, J. A., 1995 The Polycomb and trithorax group proteins of Drosophila: trans-regulators of homeotic gene function. Ann. Rev. Genet. 29: 289-303.
24. LIM, J. K., 1993 Protocol for in situ hybridization with biotinylated DNA. Dros. Inf. Serv. 72: 73-76.
25. LINDSLEY, D. L., and G. G. ZIMM, 1992 The Genome of Drosophila melanogaster. Academic Press, San Diego.
26. MAILLET, L., C. BOSCHERON, M. GOTTA , S. MARCAND, E. GILSON et al., 1996 Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression. Genes & Dev. 10: 1796-1811.
27. MARLOR, R. L., S. M. PARKHURST and V. G. CORCES, 1986 The Drosophila melanogaster gypsy transposable element encodes putative gene products homologous to retroviral proteins. Mol. Cell. Biol. 6: 1129-1134.
28. MAZO, A. M., L. J. MIZROKHI, A. A. KARAVANOV, Y. A. SEDKOV, A. A. KRICHEVSKAJA et al., 1989 Suppression in Drosophila: su(Hw) and su(f) gene products interact with a region of gypsy (mdg4) regulating its transcriptional activity. EMBO J. 8: 903-911.
29. MCCALL, K., and W. BENDER, 1996 Probes for chromatin accessibility in the Drosophila bithorax complex respond differently to Polycomb-mediated repression. EMBO J. 15: 569-580.
30. MCKEON, J., and H. W. BROCK, 1991 Interactions of the Polycomb group of genes with homeotic loci of Drosophila. Roux's Arch. Dev. Biol. 199: 387-396.
31. MCKEON, J., E. SLADE, D. A. R. SINCLAIR, N. CHENG, M. COULING et al., 1994 Mutations in some Polycomb group genes of Drosophila interfere with regulation of segmentation genes. Mol. & Gen. Gent. 244: 474-483.
32. MOASED, D., and P. H. O'FARRELL, 1992 Maintenance of the engrailed expression pattern by Polycomb group genes in Drosophila. Development 116: 805-810.
33. MODOLELL, J., W. BENDER and M. MESELSON, 1983 D. melanogaster mutations suppressible by the suppressor of Hairy-wing are insertions of a 7.3 kb mobile element. Proc. Natl. Acad. Sci. USA 80: 1678-1682.
34. PARKHURST, S. M., D. A. HARRISON, M. P. REMINGTON, C. SPANA, R. L. KELLEY et al., 1988 The Drosophila su(Hw) gene, which controls the phenotypic effect of the gypsy transposable element, encodes a putative DNA binding protein. Genes & Dev. 2: 1205-1215.
35. PARO, R., 1990 Imprinting a determined state into the chromatin of Drosophila. Trends Genet. 6: 416-421.
36. PEIFER M., and W. BENDER, 1986 The anterobithorax and bithorax mutations of the bithorax complex. EMBO J. 9: 2293-2303.
37. PEIFER M., and W. BENDER, 1988 Sequences of the gypsy transposon of Drosophila necessary for its effects on adjacent genes. Proc. Natl. Acad. Sci. USA 85: 9650-9654.
38. PELEGRI, F., and R. LEHMANN, 1994 A role of Polycomb group genes in the regulation of gap gene expression in Drosophila. Genetics 136: 1341-1354.
39. PIRROTTA, V., 1988 Vectors for P-mediated transformation in Drosophila, pp. 437-445 in Vectors. A Survey of Molecular Cloning Vectors and Their Uses, edited by R. L. RODRIQUEZ and D. T. DENHARDT. Buttersworths, Boston.
40. PIRROTTA, V., 1997 Pc-G complexes and chromatin silencing. Curr. Opin. Gen. Dev. 7: 249-258.
41. PIRROTTA, V., and L. RASTELLI, 1994 white gene expression, repressive chromatin domains and homeotic gene regulation. Bioessays 16: 549-556.
42. POUX, S., C. KOSTIC and V. PIRROTTA, 1996 Hunchback-independent silencing of late Ubx enhancers by a Polycomb group response element. EMBO J. 15: 4713-4722.
43. QIAN, S., B. VARJAVAND and V. PIRROTTA, 1992 Molecular analysis of the zeste-white interaction reveals a promoter-proximal element essential for distant enhancer-promoter communication. Genetics 131: 79-90.
44. RASTELLI, L., C. S. CHAN and V. PIRROTTA, 1993 Related chromosome binding sites for zeste, suppressors of zeste and Polycomb group proteins in Drosophila and their dependence on Enhancer of zeste function. EMBO J. 12: 1523-1522.
45. ROBERTSON, H. M., C. R. PRESTON, R. W. PHILLIS, D. JOHNSON-SCHLITZ, W. K. BENZ et al., 1988 A stable source of P element transposase. Genetics. 118: 461-470.
46. ROSEMAN, R. R., V. PIRROTTA and P. K. GEYER, 1993 The su(Hw) protein insulates expression of the Drosophila melanogaster white gene from chromosomal position-effects. EMBO J. 12: 435-442.
47. ROSEMAN, R. R., E. A. JOHNSON, C. K. RODESCH, M. BJERLE, R. N. NAGOSHI et al., 1995 A P-element containing suppressor of Hairy-wing binding regions has novel properties for mutagenesis in Drosophila melanogaster. Genetics 141: 1061-1074.
48. RUBIN, G. M., and A. C. SPRADLING, 1982 Genetic transformation of Drosophila with transposable element vectors. Science 218: 348-353.
49. SCOTT, K. S., and P. K. GEYER, 1995 Effects of the su(Hw) insulator protein on the expression of the divergently transcribed yolk-protein genes. EMBO J. 14: 6258-6279.
50. SIMON, J., 1995 Locking in stable states of gene expression: transcriptional control during Drosophila development. Curr. Opin. Cell. Biol. 7: 376-385.
51. SIMON, J., M. PEIFER, W. BENDER and M. O'CONNOR, 1990 Regulatory elements of the bithorax complex that control expression along the anterior-posterior axis. EMBO J. 9: 3945-3956.
52. SIMON, J., A. C. CHIANG, W. BENDER, M. J. SHIMELL and M. O'CONNOR, 1993 Elements of the Drosophila bithorax complex that mediate repression by Polycomb group products. Dev. Biol. 158: 131-144.
53. SMITH, P. A., and V. G. CORCES, 1992 The suppressor ot Hairy-wing binding region is required for gypsy mutagenesis. Mol. & Gen. Genet. 233: 65-70.
54. SPANA, C., D. A. HARRISON and V. G. CORCES, 1988 The Drosophila melanogaster suppressor of Hairy-wing protein binds to specific sequences of the gypsy retrotransposon. Genes & Dev. 2: 1414-1423.
55. STRUHL, G., and M. AKAM, 1985 Altered distributions of Ultrabithorax transcripts in extra sex combs mutant embryos of Drosophila. EMBO J. 4: 3259-3264.
56. STRUTT, H., G. CAVALLI and R. PARO, 1997 Co-localization of Polycomb protein and GAGA factor on regulatory elements responsible for the maintenance of homeotic gene expression. EMBO J. 16: 3621-3632.
57. WAKIMOTO, B. T., and M. G. HEARN, 1990 The effects of chromosome rearrangements on the expression of heterochromatic genes in chromosome 2L of Drosophila melanogaster. Genetics 125: 141-154.
58. ZHOU, J, S. BAROLO, P. SZYMANSKI and M. LEVINE, 1996 The Fab-7 element of the bithorax complex attenuates enhancer-promoter interactions in the Drosophila embryo. Genes & Dev. 10: 3195-3201.
59. ZINK, D., and R. PARO, 1989 In vivo binding pattern of a trans-regulator of homeotic genes in Drosophila melanogaster. Nature 437: 468-471.
60. ZINK, D., and R. PARO, 1995 Drosophila Polycomb-group related chromatin inhibits the accessibility of a trans-activator to its target DNA. EMBO J. 14: 5660-5671.