The Saccharomyces cerevisiae start-specific transcription factor Swi4 interacts through the ankyrin repeats with the mitotic Clb2/Cdc28 kinase and through its conserved carboxy terminus with Swi6

Molecular and Cellular Biology

Volumn 16, Issue 6, 1996, Pages 2647-2655

  Siegmund, Robert F ^a   Nasmyth, Kim A ^a  

^a RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ANKYRIN; TRANSCRIPTION FACTOR;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE; CELL SIZE; MITOSIS; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

SACCHAROMYCES CEREVISIAE;

EID: 0029954321     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.6.2647     Document Type: Article

References (59)

1. Aman, A., M. Tyers, B. Futcher, and K. Nasmyth. 1993. Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins. Cell 74:993-1007.
2. Andrews, B. J., and I. Herskowitz. 1989. Identification of a DNA binding factor involved in cell-cycle control of the yeast HO gene. Cell 57:21-29.
3. Andrews, B. J., and L. Moore. 1992. Mutational analysis of a DNA sequence involved in linking gene expression to the cell cycle. Biochem. Cell Biol. 70:1073-1080.
4. Andrews, B. J., and L. A. Moore. 1992. Interaction of the yeast Swi4 and Swi6 cell cycle regulatory proteins in vitro. Proc. Natl. Acad. Sci. USA 89:11852-11856.
5. Axton, J. M., F. L. Shamanski, L. M. Young, D. S. Henderson, J. B. Boyd, and T. L. Orr-Weaver. 1994. The inhibitor of DNA replication encoded by the Drospohila gene plutonium is a small ankyrin repeat protein. EMBO J. 13:462-470.
6. Ayte, J., J. F. Leis, A. Herrera, E. Tang, H. Yang, and J. A. DeCaprio. 1995. The Schizosaccharomyces pombe MBF complex requires heterodimerization for entry into S phase. Mol. Cell. Biol. 15:2589-2599.
7. Bork, P. 1993. Hundreds of ankyrin-like repeats in functionally diverse proteins: mobile modules that cross phyla horizontally? Proteins 17:363-374.
8. Breeden, L. Personal communication.
9. Breeden, L., and K. Nasmyth. 1987. Cell cycle control of the yeast HO gene: cis and trans acting regulators. Cell 48:389-397.
10. Breeden, L., and K. Nasmyth. 1987. Similarity between the cell cycle genes of fission yeast and budding yeast and the Notch gene of Drosophila. Nature (London) 329:651-654.
11. Caliguri, M., and D. Beach. 1993. Sell functions in partnership with Cdc10 in a transcription complex that activates cell cycle START and inhibits differentiation. Cell 72:607-619.
12. Cross, F. R. 1990. Cell cycle arrest caused by CLN gene deficiency in Saccharomyces cerevisiae resembles START-I arrest and is dependent on the mating pheromone pathway. Mol. Cell. Biol. 10:6482-6490.
13. Dirick, L., T. Boehm, and K. Nasmyth. 1995. Roles and regulation of the Cln-Cdc28 kinases at the START of the cell cycle of Saccharomyces cerevisiae. EMBO J. 14:4803-4813.
14. Dirick, L., T. Moll, H. Auer, and K. Nasmyth. 1992. A central role for SWI6 in cell-cycle start specific transcription in yeast. Nature (London) 357:508-513.
15. Dynlacht, B. D., O. Flores, J. A. Lees, and E. Harlow. 1994. Differential regulation of E2F transactivation by cyclin/cdk2 complexes. Genes Dev. 8:1772-1786.
16. Epstein, C. B., and F. R. Cross. 1992. CLB5: a novel B cyclin from budding yeast with a role in S phase. Genes Dev. 6:1695-1706.
17. Espinoza, F. H., J. Ogas, I. Herskowitz, and D. O. Morgan. 1994. Cell cycle control by a complex of the cyclin HCS26(PCL1) and the kinase PHO85. Science 266:1388-1391.
18. Fitch, I., C. Dahmann, U. Surana, A. Amon, I. Goetsch, B. Byers, and B. Futcher. 1992. Characterisation of four B-type cyclin genes of the budding yeast S. cerevisiae. Mol. Biol. Cell 3:805-818.
19. Ghiara, J. B., H. E. Richardson, K. Sugimoto, M. Henze, D. J. Lew, C. Wittenberg, and S. I. Reed. 1991. A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis. Cell 65:153-174.
20. Gietz, R. D., and A. Sugino. 1988. New yeast E. coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six base pair restriction sites. Gene 74:527-535.
21. INK4B/MTS2-related CDK6 inhibitor correlates with wild-type pRB function. Genes Dev. 8:2939-2952.
22. Hagemeier, C., A. J. Bannister, A. Cook, and T. Kouzarides. 1993. The PU. 1 activation domain binds RB and TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB. Proc. Natl. Acad. Sci. USA 90:1580-1584.
23. INK4B is a potential effector of TGF-beta-induced cell cycle arrest. Nature (London) 371:257-261.
24. Hoffmann, J. F. X., and D. Beach. 1994. Cdt1 is an essential target of the Cdc10/Sct1 transcription factor: requirement for DNA replication and inhibition of mitosis. EMBO J. 13:425-434.
25. Kelly, T. J., G. S. Martin, S. L. Forsburg, K. J. Stephen, A. Russo, and P. Nurse. 1993. The fission yeast cdc18+ gene product couples S phase to START and mitosis. Cell 74:371-382.
26. Koch, C., M. Neuberg, H. Ahorn, and K. Nasmyth. 1993. A role for the transcription factors Mbp1 and Swi4 in the progression from G1 to S-phase. Science 261:1551-1557.
27. Koch, C., A. Schleiffer, G. Ammerer, and K. Nasmyth. 1996. Switching transcription on and off during the cell cycle: Cln/Cdc28 kinases activate bound transcription factor SBF (Swi4/Swi6) at START, whereas Clb/Cdc28 kinases displace it from the promoter in G2. Genes Dev. 10:129-141.
28. Krek, W., M. E. Ewen, S. Shirodkar, Z. Arany, W. G. Kaelin, Jr., and D. M. Livingston. 1994. Negative regulation of the growth promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell 78:161-172.
29. La Thangue, N. 1994. DP and E2F proteins: components of a heteromeric transcription factor implicated in cell cycle control. Curr. Opin. Cell Biol. 6:443-450.
30. Lowndes, N., C. McIerny, A. Johnson, P. Fantes, and L. Johnston. 1992. Control of DNA synthesis genes in fission yeast by the cell cycle gene cdc10+ . Nature (London) 355:449-453.
31. Lowndes, N. F., A. L. Johnson, and L. H. Johnston. 1991. Coordination of expression of DNA synthesis genes in budding yeast by a cell cycle regulated Irans factor. Nature (London) 350:247-250.
32. Measday, V., L. Moore, J. Ogas, M. Tyers, and B. Andrews. 1994. The PCL2(ORFD)-PHO85 cyclin dependent kinase complex: a cell cycle regulator in yeast. Science 266:1391-1395.
33. Miyamoto, M., K. Tanaka, and H. Okayama. 1994. Res2+, a new member of the cdc10+/SW14 family, controls the "Start" of mitotic and meiotic cell cycles in fission yeast. EMBO J. 13:1863-1872.
34. Nasmyth, K. 1985. A repetitive DNA sequence that confers cell-cycle START (CDC28) dependent transcription of the HO gene in yeast. Cell 42:225-235.
35. Nasmyth, K. 1993. Control of the yeast cell cycle by the Cdc28 protein kinase. Curr. Opin. Cell Biol. 5:166-179.
36. Nasmyth, K., and L. Dirick. 1991. The role of SWI4 and SWI6 in the activity of G1 cyclins in yeast. Cell 66:995-1013.
37. Neuberg, M. Personal communication.
38. Ogas, J., B. J. Andrews, and I. Herskowitz. 1991. Transcriptional activation of CLN1, CLN2 and a putative new G1 cyclin (HCS26) by SWI4, a positive regulator of G1 specific transcription. Cell 66:1015-1026.
39. i signals in Saccharomyces cervisiae. Mol. Cell. Biol. 15:997-1004.
40. Pardee, A. B. 1989. G1 events and regulation of cell proliferation. Science 246:603-608.
41. Primig, M., S. Sockanathan, H. Auer, and K. Nasmyth. 1992. Anatomy of a transcription factor important for the start of the cell cycle in S. cerevisae. Nature (London) 358:593-597.
42. Reed, S. I. 1992. The role of p34 kinases in the G1 to S-phase transition. Annu. Rev. Cell Biol. 8:529-561.
43. cdc10 function. Mol. Gen. Genet. 234:449-456.
44. Richardson, H., D. J. Lew, K. Sugimoto, and S. I. Reed. 1992. Cyclin B homologs in Saccharomyces cerevisiae function in S phase and in G2. Genes Dev. 6:2021-2034.
45. Richardson, H. E., C. Wittenberg, F. Cross, and S. I. Reed. 1989. An essential G1 function for cyclin like proteins in yeast. Cell 59:1127-1133.
46. Schneider, K. R., R. L. Smith, and E. K. O'Shea. 1994. Phosphate regulated inactivation of the kinase PHO80-PHO85 by the CDK inhibitor PHO81. Science 266:122-126.
47. SIC1 controls the G1 to S transition in S. cerevisiae. Cell 79:233-244.
48. Schwob, E., and K. Nasmyth. 1993. CLB5 and CLB6, a new pair of B cyclins involved DNA replication in Saccharomyces cerevisiae. Genes Dev. 7:1160-1175.
49. Serrano, M., G. J. Hannon. and D. Beach. 1993. A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4. Nature (London) 366:704-707.
50. 1/S-specific transcription in Saccharomyces cerevisiae. Mol. Cell. Biol. 13:1069-1077.
51. Smith, D. B., and K. S. Johnson. 1988. Single step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67:31-40.
52. Sockanathan, S. 1990. Ph.D. thesis. University of Cambridge, Cambridge, England.
53. Surana, U., H. Robitsch, C. Price, T. Schuster, I. Fitch, A. B. Futcher, and K. Nasmyth. 1991. The role of Cdc28 and cyclins during mitosis in the budding yeast S. cerevisiae. Cell 65:145-161.
54. Taba, M. R. M., I. Muroff, D. Lydall, G. Tebb, and K. Nasmyth. 1991. Changes in a Swi4,6-DNA-binding complex occur at the time of HO activation in yeast. Genes Dev. 5:2000-2013.
55. Tanaka, K., K. Okakzaki, N. Okazaki, T. Ueda, A. Sugiyama, H. Nojima, and H. Okayama. 1992. A new cdc gene required for S phase entry in Schizosaccharomyces pombe encodes a protein similar to cdc10 + and SWI4 gene products. EMBO J. 11:4923-4932.
56. Tyers, M., G. Tokiwa, and B. Futcher. 1993. Comparison of the Saccharomyces cerevisae G1 cyclins: Cln3 may he an upstream activator of Cln 1, Cln2 and other cyclins. EMBO J. 12:1955-1968.
57. Tyers, M., G. Tokiwa, R. Nash, and B. Futcher. 1992. The Cln3-Cdc28 kinase complex of S. cerevisae is regulated by proteolysis and phosphorylation. EMBO J. 11:1773-1784.
58. Xu, M., K.-A. Sheppard, C.-V. Peng, A. S. Yee, and H. Piwnica-Worms. 1994. Cyclin A/Cdk2 binds directly to E2F-1 and inhibits the DNA binding activity of E2F-1/DP-1 by phosphorylation. Mol. Cell. Biol. 14:8420-8431.
59. cdc10, is required for meiosis in the fission yeast Schizosaccharomyces pombe. Genes Dev. 8:885-898.