Orphanin FQ inhibits capsaicin-induced thermal nociception in monkeys by activation of peripheral ORL1 receptors

British Journal of Pharmacology

Volumn 135, Issue 4, 2002, Pages 943-950

  Ko, M C H ^a   Naughton, N N ^a   Traynor, J R ^a   Song, M S ^a   Woods, J H ^a   Rice, K C ^b   McKnight, A T ^c  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c Oxford Natural Products   (United Kingdom)

Author keywords

Antinociception; Capsaicin; Hyperalgesia; ORL1 receptors; Orphanin FQ; Peripheral tissues; Primary afferent nociceptors

Indexed keywords

1 (1 CYCLOOCTYLMETHYL 3 HYDROXYMETHYL 4 PIPERIDYL) 3 ETHYL 1,3 DIHYDRO 2H BENZIMIDAZOL 2 ONE; 3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; 4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 HYDROXYBENZYL] N,N DIETHYLBENZAMIDE; BINALTORPHIMINE; CAPSAICIN; DELTA OPIATE RECEPTOR; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR; NALTRINDOLE; NOCICEPTIN; OPIATE RECEPTOR; QUADAZOCINE;

ALLODYNIA; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG MECHANISM; FEMALE; HYPERALGESIA; MALE; MONKEY; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; TAIL FLICK TEST; TIME SERIES ANALYSIS;

ANIMALS; BENZIMIDAZOLES; CAPSAICIN; FEMALE; HEATING; MACACA MULATTA; MALE; OPIOID PEPTIDES; PAIN; PIPERIDINES; RECEPTORS, OPIOID; TAIL;

EID: 0036185102     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704535     Document Type: Article

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