Pancreatic cell lines: A review

Pancreas

Volumn 24, Issue 2, 2002, Pages 111-120

  Ulrich, Alexis B ^a   Schmied, Bruno M ^a   Standop, Jens ^a   Schnieder, Matthias B ^a   Pour, Parviz M ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Cell lines; Pancreas; Review

Indexed keywords

CANCER CELL CULTURE; CELL DIFFERENTIATION; CELL TRANSFORMATION; CHROMOSOME ABERRATION; GENE MUTATION; HUMAN; PANCREAS CANCER; PRIORITY JOURNAL; REVIEW;

ANIMALS; CELL CULTURE TECHNIQUES; HUMANS; ISLETS OF LANGERHANS; PANCREATIC DUCTS; PANCREATIC NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 0036182651     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006676-200203000-00001     Document Type: Review

References (119)

1. Cancer statistics, 1997
2. Lymph node involvement in carcinoma of the head of the pancreas area
3. Pancreatic cancer
4. Experimental carcinogenesis in the pancreas
5. Overexpression of TGF alpha in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast
6. Rapid acinar to ductal transdifferentiation in cultured human exocrine pancreas
7. Experimental pancreatic cancer
8. Pancreatic neoplasia induced by SV40 T-antigen expression in acinar cells of transgenic mice
9. Pancreatic tumor pathogenesis reflects the causative genetic lesion
10. TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas
11. Activation of c-K-ras is frequent in pancreatic carcinomas of Syrian hamsters, but is absent in pancreatic tumors of rats
12. K-ras and p53 gene mutations in pancreatic cancer: Ductal and nonductal tumors progress through different genetic lesions
13. In vitro pancreatic ductal cell carcinogenesis
14. Mechanistic analysis of pancreatic ductal carcinogenesis in hamsters
15. One thousand faces of Langerhans islets
16. Differences in molecular biological, biological and growth characteristics between the immortal and malignant hamster pancreatic cells
17. Characterization of differentiated Syrian golden hamster pancreatic duct cells maintained in extended monolayer culture
18. Characterization of ducts isolated from the pancreas of the rat
19. Isolation and culture of hamster pancreatic ducts
20. Immortalized pancreatic duct cells in vitro and in vivo
21. Establishment of propagable epithelial cell lines from normal adult rat pancreas
22. Isolation and characterization of epithelial cells from bovine pancreatic duct
23. Characterization of bovine pancreatic ductal cells isolated by a perfusion-digestion technique
24. Dog pancreatic duct epithelial cells: Long-term culture and characterization
25. Immortalization of bovine pancreatic duct epithelial cells
26. Growth and function of isolated canine pancreatic ductal cells
27. A new culture method for human pancreatic islets using a biopore membrane insert
28. Improved quality and yield of islets isolated from human pancreata using a two-step digestion method
29. The pancreatic duct cell: Proliferative capabilities, specific characteristics, metaplasia, isolation, and culture
30. Stereological analysis of the guinea pig pancreas. I. Analytical model and quantitative description of nonstimulated pancreatic exocrine cells
31. Rat pancreas adenylate cyclase V. Its presence in isolated rat pancreatic acinar cells
32. Comparative morphometric study of the human pancreas in its normal state and in primary chronic calcifying pancreatitis
33. Establishment and characterization of a new, spontaneously immortalized, pancreatic ductal cell line from the Syrian golden hamster
34. Isolation and monolayer culture of guinea pig pancreatic duct epithelial cells
35. Isolation and culture of bovine pancreatic duct epithelial cells
36. Carcinogenesis in the pancreas. I. Long-term explant culture of human and bovine pancreatic ducts
37. Culture of human main pancreatic duct epithelial cells
38. Isolation, culture, and characterization of human pancreatic duct cells
39. Long-term culture and immortalization of epithelial cells from normal adult human pancreatic ducts transfected by the E6E7 gene of human papilloma virus 16
40. Increasing the transfection efficacy and subsequent long-term culture of resting human pancreatic duct epithelial cells
41. In vitro carcinogenesis of hamster pancreatic duct cells: Cellular and molecular alterations
42. Assignment of SV40-immortalized cells to more than one complementation group for immortalization
43. Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen
44. Cytogenetic study of 11 gastric adenocarcinomas
45. Enhanced fibroblast growth factor 5 expression in stromal and exocrine elements of the pancreas in chronic pancreatitis
46. Establishment of human pancreatic ductal cells in a long-term culture
47. The Banting Memorial Lecture 1973: Islet differentiation, organ culture, and transplantation
48. Tissue culture isolation and preservation of human cadaveric pancreatic islets
49. In vitro-generation of islets in long-term cultures of pluripotent stem cells from adult mouse pancreas
50. In vitro cultivation of human islets from expanded ductal tissue
51. Long-term culture of human pancreatic islets in an extracellular matrix: Morphological and metabolic effects
52. Transdifferentiation of human islets to pancreatic ductal cells in collagen matrix culture
53. Sustained proliferation of PDX-1+ cells derived from human islets
54. Prolonged survival of adult rat pancreatic islets transfected with E1A-12S adenovirus
55. Differentiation of islet cells in long-term culture
56. Maintenance of human islets in long-term culture
57. Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets
58. Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene
59. Functional pancreatic betacell line from SV40 T-antigen transgenic mouse
60. Pancreatic beta cells cultured from individual preneoplastic foci in a multistage tumorigenesis pathway: A potentially general technique for isolating physiologically representative cell lines
61. Glucose metabolism and insulin release in mouse beta HC9 cells, as model for wild-type pancreatic beta-cells
62. Insulin synthesis in a clonal cell line of simian virus 40-transformed hamster pancreatic beta cells
63. Continuous, clonal, insulinand somatostatin-secreting cell lines established from a transplantable rat islet cell tumor
64. Regulation of immunoreactive-insulin release from a rat cell line (RINm5F)
65. Establishment of 2-mercaptoethanol-dependent differentiated insulin- secreting cell lines
66. Five new insulinproducing cell lines with differing secretory properties
67. NIT-1, a pancreatic betacell line established from a transgenic NOD/Lt mouse
68. Isolation and characterization of a cell line from the epithelial cells of the human fetal pancreas
69. Beta-cell differentiation from a human pancreatic cell line in vitro and in vivo
70. Development of engineered pancreatic beta-cell lines for cell therapy of diabetes
71. Isolation of glucagon-secreting cell lines by cloning insulinoma cells
72. Proglucagon processing similar to normal islets in pancreatic alpha-like cell line derived from transgenic mouse tumor
73. Insulin, glucagon, and somatostatin secretion by cultured rat islet cell tumor and its clones
74. Characteristics of two rat pancreatic exocrine cell lines derived from transplantable tumors
75. Recent results in animal models of pancreatic carcinoma: Histogenesis of tumors
76. Transplantation of azaserine-induced carcinomas of pancreas in rats
77. Transdifferentiation of human islets in long-term culture
78. Ductal cyst formation in collagen-embedded adult human islet preparations: A means to the reproduction of nesidioblastosis in vitro
79. Differentiation of pancreatic acinar cells into duct-like cells in vitro
80. Establishment of hamster pancreatic ductal carcinoma cell line (PC-1) producing blood group-related antigens
81. Chemotherapy of pancreatic adenocarcinoma: Initial report on two transplantable models in the Syrian hamster
82. Establishment and characterization of a new hamster pancreatic cancer cell line: The biological activity and the binding characteristics of EGF or TGF-alpha
83. Expression of the human MUC1 mucin cDNA in a hamster pancreatic tumor cell line HP-1
84. Establishment and characterization of a cultured cell line derived from nitrosamine-induced pancreatic ductal adenocarcinoma in Syrian golden hamsters
85. Development of a transplantable model of pancreatic duct adenocarcinoma
86. Characterization of three cloned cell lines from a N-nitrosobis(2-hydroxypropyl)amine-induced transplantable hamster pancreatic ductal adenocarcinoma
87. Production of scatter factorlike activity by a nitrosamine-induced pancreatic cancer cell line
88. Relationship between blood group-A antigen expression and malignant potential in hamster pancreatic cancers
89. Experimental evidence for the origin of ductal-type adenocarcinoma from the islets of Langerhans
90. Induction of adenocarcinoma from hamster pancreatic islet cells treated with N-nitrosobis(2-oxopropyl)amine in vitro
91. Biologic instability of pancreatic cancer xenografts in the nude mouse
92. Tumor-suppressive pathways in pancreatic carcinoma
93. Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
94. K-ras oncogene activation in adenocarcinoma of the human pancreas: A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization
95. p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions
96. Frequent somatic mutations and homozygous deletions of the p16 (MTSI) gene in pancreatic adenocarcinoma
97. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
98. K-ras and p53 mutations in hamster pancreatic ductal adenocarcinomas and cell lines
99. Comparison of p53 protein expression and cellular localization in human and hamster pancreatic cancer cell lines
100. p53 mutation without allelic loss and absence of mdm-2 amplification in a transplantable hamster pancreatic ductal adenocarcinoma and derived cell lines but not primary ductal adenocarcinomas in hamsters
101. Comparative genomic hybridization reveals frequent gains of 20q, 8q, 11q, 12p, and 17q, and losses of 18q, 9p, and 15q in pancreatic cancer
102. Karyotypic abnormalities in tumours of the pancreas
103. Nonrandom chromosomal rearrangements in pancreatic carcinomas
104. Cytogenetic findings in metastases from colorectal cancer
105. Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver
106. Establishment of tumor cell culture (ILA) derived from hamster pancreatic islets treated with BOP
107. Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha
108. Production of transforming growth factor alpha in human pancreatic cancer cells: Evidence for a superagonist autocrine cycle
109. Transforming growth factor-alpha: A more potent angiogenic mediator than epidermal growth factor
110. Transforming growth factor alpha is trophic to pancreatic cancer in vivo
111. The role of angiogenesis in the tumor growth of Syrian hamster pancreatic cancer cell line HPD-NR
112. Characterization of cancer cell dissociation factor in a highly invasive pancreatic cancer cell line
113. Lectin binding affinities of induced pancreatic lesions in the hamster model
114. Blood-group antigen expression during pancreatic cancer induction in hamsters
115. Blood group antigen expression in developing pancreas and in induced pancreatic cancer cells in Syrian hamsters
116. Shortened telomere length and increased telomerase activity in hamster pancreatic duct adenocarcinomas and cell lines
117. Variable effect of streptozotocin-diabetes on the growth of hamster pancreatic cancer (H2T) in the Syrian hamster and nude mouse
118. Cell lines of the human and rodent exocrine pancreas