Estrogen replacement therapy induces telomerase RNA expression in the macaque endometrium

Fertility and Sterility

Volumn 77, Issue 3, 2002, Pages 601-608

  Vidal, Justin D ^a,c   Register, Thomas C ^b   Gupta, Madhu ^b   Cline, J Mark ^b  

^a VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Endometrium; Estrogen; Hormone replacement therapy; Macaque; Medroxyprogesterone acetate; Tamoxifen; Telomerase; Telomerase RNA

Indexed keywords

CONJUGATED ESTROGEN; MEDROXYPROGESTERONE ACETATE; RNA; TAMOXIFEN; TELOMERASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ENDOMETRIUM; ENZYME ACTIVITY; ESTROGEN THERAPY; FEMALE; GENE EXPRESSION REGULATION; HORMONAL REGULATION; HORMONAL THERAPY; HORMONE SUBSTITUTION; LUTEAL PHASE; MACACA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STROMA CELL; TELOMERE;

ANIMALS; ENDOMETRIUM; ESTROGEN REPLACEMENT THERAPY; ESTROGENS, CONJUGATED (USP); FEMALE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; KI-67 ANTIGEN; MACACA FASCICULARIS; MEDROXYPROGESTERONE 17-ACETATE; RANDOM ALLOCATION; RNA; SELECTIVE ESTROGEN RECEPTOR MODULATORS; TAMOXIFEN; TELOMERASE;

EID: 0036182513     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(01)03227-7     Document Type: Article

References (47)

1. Telomeres; beginning to understand the end
2. Multiple pathways for the regulation of telomerase activity
3. Telomerase and the end replication problem
4. The limited reproductive life span of normal cells in culture
5. Expression of telomerase subunits and correlation with telomerase activity in cervical cancer
6. Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span
7. Telomerase and early detection of cancer; a national cancer institute workshop
8. A survey of telomerase activity in human cancer
9. The RNA component of human telomerase
10. Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues
11. Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis
12. Amplification increased dosage and in situ expression of the telomerase RNA gene in human cancer
13. Human telomerase reverse transcriptase as a critical determinant of telomerase activity in normal and malignant endometrial tissues
14. Telomerase activity in benign endometrium and endometrial carcinoma
15. Telomerase activity in human endometrium
16. Proliferation-associated regulation of telomerase activity in human endometrium and its potential implication in early cancer diagnosis
17. Telomerase activity in the human endometrium throughout the menstrual cycle
18. Expression of telomerase activity in human endometrium is localized to epithelial glandular cells and regulated in a menstrual phase-dependent manner correlated with cell proliferation
19. Telomerase activity is found in the epithelial cells but not in the stromal cells in human endometrial cell culture
20. Hormone therapy to prevent disease and prolong life in postmenopausal women
21. Potential role of tamoxifen in prevention of breast cancer
22. Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial
23. Prevention of breast cancer with tamoxifen; preliminary findings from the Italian randomised trial among hysterectomised women
24. Pathology of endometrium treated with tamoxifen
25. Effects of tamoxifen on uterus and ovaries of postmenopausal women in a randomised breast cancer trial
26. Endometrial cancer
27. Significance of benign uterine pathology on tamoxifen
28. Reproduction in the rhesus monkey Macaca mulatta
29. Cyclic changes in the primate oviduct and endometrium
30. Assessment of hormonally active agents in the reproductive tract of female nonhuman primates
31. Telomerase activity and in situ telomerase RNA expression in malignant and non-malignant lymph nodes
32. Effects of hormone replacement therapy on the mammary gland of surgically postmenopausal cynomolgus macaques
33. A morphometric filter improves the diagnostic value of morphometric analyses of frozen histopathological sections from mammary tumors
34. Natural history investigation and staging of carcinoma of the endometrium
35. Analysis of telomerase expression and proliferative activity in the different layers of cyclic endometrium
36. Cyclic fluctuations in the rate of epithelial mitosis in the endometrium of the rhesus monkey
37. Zonal changes in proliferation in the rhesus endometrium during the late secretory phase and menses
38. Molecular mechanisms of estrogen carcinogensis
39. Telomerase activity in gynecological tumors
40. Telomerase expression in normal endometrium endometrial hyperplasia and endometrial adenocarcinoma
41. Telomerase activity in the female reproductive tract and neoplasms
42. Induction of covalent DNA adducts in rodents by tamoxifen
43. Lack of genotoxicity of tamoxifen in human endometrium
44. Tamoxifen-induced DNA adducts in endometrial samples from breast cancer patients
45. Alterations steroid hormone receptors in the tamoxifen-treated endometrium
46. Insulin-like growth factor I gene expression in the uterus is stimulated by tamoxifen and inhibited by the pure antiestrogen ICI 182780
47. Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP)