In vitro cytocidal effects on Trypanosoma brucei and inhibition of Leishmania major GP63 by peptidomimetic metalloprotease inhibitors

Molecular and Biochemical Parasitology

Volumn 114, Issue 1, 2001, Pages 111-117

  Bangs, James D ^a   Ransom, Dawn A ^a   Nimick, Mhairi ^b   Christie, Gary ^c   Hooper, Nigel M ^b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF LEEDS   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

GP63; Leishmania; Metalloprotease; Peptidomimetic; Trypanosomes

Indexed keywords

BB 3103; BRL 29808; BRL 48226; BRL 49244; BRL 54525; BRL 57240; CAPTOPRIL; CERANAPRIL; ENALAPRILAT; FOSINOPRILAT; GLYCOPROTEIN; LEISHMANOLYSIN; MEMBRANE PROTEIN; METALLOPROTEINASE; METALLOPROTEINASE INHIBITOR; PENTOPRILAT; PHOSPHORAMIDON; RENTIAPRIL; SB 201140; SB 202968Z; SB 227961; SB 227962; THIORPHAN; UNCLASSIFIED DRUG; VARIANT SURFACE GLYCOPROTEIN; ZINCOV;

ARTICLE; CELL SURFACE; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVITY; FLAGELLATE; GENE EXPRESSION; GENETIC CODE; IC 50; LEISHMANIA MAJOR; LIFE CYCLE; NONHUMAN; PARASITOSIS; PRIORITY JOURNAL; TRYPANOSOMA; TRYPANOSOMA BRUCEI;

ANIMALS; ANTIPROTOZOAL AGENTS; KINETICS; LEISHMANIA MAJOR; METALLOENDOPEPTIDASES; MOLECULAR STRUCTURE; PEPTIDES; PROTEASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOSOMA BRUCEI BRUCEI; VARIANT SURFACE GLYCOPROTEINS, TRYPANOSOMA;

EID: 0035946347     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(01)00244-4     Document Type: Article

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