Stage-specific expression in Leishmania conferred by 3′ untranslated regions of L. major leishmanolysin genes (GP63)

Molecular and Biochemical Parasitology

Volumn 116, Issue 1, 2001, Pages 101-104

  Kelly, Ben L ^a   Nelson, Tanya N ^a   McMaster, W Robert ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Leishmania; Reporter gene assay; Stage specific expression

Indexed keywords

HYGROMYCIN B; MESSENGER RNA; METALLOPROTEINASE; PLASMID DNA; THYMIDINE KINASE; ZINC;

AMASTIGOTE; ARTICLE; CONTROLLED STUDY; DNA FLANKING REGION; GENE CONSTRUCT; GENE CONTROL; GENE EXPRESSION; GENE SEQUENCE; GENETIC CODE; GENETIC TRANSCRIPTION; HERPES SIMPLEX VIRUS; LEISHMANIA; LEISHMANIA CHAGASI; LEISHMANIA DONOVANI; LEISHMANIA MAJOR; LEISHMANIA MEXICANA; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE VECTOR; PRIORITY JOURNAL; PROMASTIGOTE; REGULATOR GENE; REGULATORY MECHANISM; REPORTER GENE; RNA HYBRIDIZATION; TRANSCRIPTION REGULATION;

3' UNTRANSLATED REGIONS; ANIMALS; CELL DIFFERENTIATION; GENES, PROTOZOAN; LEISHMANIA MAJOR; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA;

HERPES; LEISHMANIA DONOVANI; LEISHMANIA DONOVANI CHAGASI; LEISHMANIA MAJOR; LEISHMANIA MEXICANA; PROTOZOA; SIMPLEXVIRUS;

EID: 0034895706     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(01)00307-3     Document Type: Article

References (20)

1. Differential regulation of multiple glucose transporter genes in Leishmania mexicana
2. Cloning from Leishmania major of a developmentally regulated gene c-lpk2 for the catalytic subunit of the cAMP dependent protein kinase
3. The developmental expression of Leishmania donovani A2 amastigote-specific genes is post-transcriptionally mediated and involves elements located in the 3′-untranslated region
4. A regulatory role for the 5′ and 3′ untranslated regions in differential expression of hsp83 in Leishmania
5. Expression of heat shock protein 83 in Leishmania is regulated post-transcriptionally
6. The effect of ongoing protein synthesis on the steady state levels of GP63 RNAs in Leishmania chagasi
7. Intergenic regions between tandem gp63 genes influence the differential expression of gp63 RNAs in Leishmania chagasi promastigotes
8. Differentially expressed Leishmania major gp63 genes encode cell surface leishmanolysin with distinct signals for glycosylphosphatidylinositol attachment
9. Structurally distinct genes for the surface protease of Leishmania mexicana are developmentally regulated
10. Heterogeneity of the genes encoding the major surface glycoprotein of Leishmania donovani
11. Sequence heterogeneity and polymorphic gene arrangements of the Leishmania guyanensis gp63 genes
12. Three distinct RNAs for the surface protease GP63 are differentially expressed during development of Leishmania donovani chagasi promastigotes to an infectious form
13. Targeted gene deletion of Leishmania major genes encoding developmental stage-specific leishmanolysin GP63
14. Developmental life cycle of Leishmania - Cultivation and characterization of cultured extracellular amastigotes
15. Plasmid-encoded hygromycin B resistance: The sequence of hygromycin B phosphotransferase gene and its expression in Escherichia coli and Saccharomyces cerevisiae
16. The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene
17. Characterization of a multi-copy gene for a major stages-specific cysteine proteinase of Leishmania mexicana
18. Developmental regulation of spliced leader RNA gene in Leishmania donovani amastigotes is mediated by specific polyadenylation
19. Coupling of polyA site selection and trans-splicing in Leishmania
20. Genes encoding the major surface glycoprotein in Leishmania are tandemly linked at a single chromosomal locus and are constitutively transcribed