-
1
-
-
0032869255
-
HIV-1 evolution under pressure of protease inhibitors: Climbing the stairs of viral fitness
-
(1999)
J. Biomed. Sci.
, vol.6
, pp. 298-305
-
-
Berkhout, B.1
-
2
-
-
0028943992
-
In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors
-
(1995)
Nature
, vol.374
, pp. 569-571
-
-
Condra, J.H.1
Schleif, W.A.2
Blahy, O.M.3
Gabryelski, L.J.4
Graham, D.J.5
Quintero, J.C.6
Rhodes, A.7
Robbins, H.L.8
Roth, E.9
Shivaprakash, M.10
Titus, D.11
Yang, T.12
Teppler, H.13
Squires, K.E.14
Deutsch, P.J.15
Emini, E.A.16
-
7
-
-
0343183245
-
Antiretroviral drug resistance testing in adult HIV-1 infection: Recommendations of an International AIDS Society-USA Panel
-
(2000)
JAMA
, vol.283
, pp. 2417-2426
-
-
Hirsch, M.S.1
Brun-Vezinet, F.2
D'Aquila, R.T.3
Hammer, S.M.4
Johnson, V.A.5
Kuritzkes, D.R.6
Loveday, C.7
Mellors, J.W.8
Clotet, B.9
Conway, B.10
Demeter, L.M.11
Vella, S.12
Jacobsen, D.M.13
Richman, D.D.14
-
8
-
-
17344390474
-
Antiretroviral drug resistance testing in adults with HIV infection: Implications for clinical management. International AIDS Society-USA Panel
-
(1998)
JAMA
, vol.279
, pp. 1984-1991
-
-
Hirsch, M.S.1
Conway, B.2
D'Aquila, R.T.3
Johnson, V.A.4
Brun-Vezinet, F.5
Clotet, B.6
Demeter, L.M.7
Hammer, S.M.8
Jacobsen, D.M.9
Kuritzkes, D.R.10
Loveday, C.11
Mellors, J.W.12
Vella, S.13
Richman, D.D.14
-
9
-
-
0029824426
-
In vivo resistance to a human immunodeficiency virus type 1 proteinase inhibitor: Mutations, kinetics, and frequencies
-
(1996)
J. Infect. Dis.
, vol.173
, pp. 1379-1387
-
-
Jacobsen, H.1
Hanggi, M.2
Ott, M.3
Duncan, I.B.4
Owen, S.5
Andreoni, M.6
Vella, S.7
Mous, J.8
-
10
-
-
0028846226
-
Crystal structure of HIV-1 protease in complex with VX478, a potent and orally bioavailable inhibitor of the enzyme
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 1181-1182
-
-
Kim, E.E.1
Baker, C.T.2
Dwyer, M.D.3
Mureko, B.G.4
Rao, B.G.5
Tung, R.D.6
Navia, M.A.7
-
11
-
-
0005241362
-
Active human immunodeficiency virus protease is required for viral infectivity
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 4686-4690
-
-
Kohl, N.E.1
Emini, E.A.2
Schleif, W.A.3
Davis, L.J.4
Heimbach, J.C.5
Dixon, R.A.6
Scolnick, E.M.7
Sigal, I.S.8
-
12
-
-
15844378825
-
Extensive polymorphisms observed in HIV-1 clade B protease gene using high-density oligonucleotide arrays
-
(1996)
Nat. Med.
, vol.2
, pp. 753-759
-
-
Kozal, M.J.1
Shah, N.2
Shen, N.3
Yang, R.4
Fucini, R.5
Merigan, T.C.6
Richman, D.D.7
Morris, D.8
Hubbell, E.9
Chee, M.10
Gingeras, T.R.11
-
14
-
-
1942534433
-
Structural and kinetic analysis of drug resistant mutants of HIV-1 protease
-
(1999)
Eur. J. Biochem.
, vol.263
, pp. 238-245
-
-
Mahalingam, B.1
Louis, J.M.2
Reed, C.C.3
Adomat, J.M.4
Krouse, J.5
Wang, Y.F.6
Harrison, R.W.7
Weber, I.T.8
-
15
-
-
0031846317
-
Resistance-associated loss of viral fitness in human immunodeficiency virus type 1: Phenotypic analysis of protease and Gag coevolution in protease inhibitor-treated patients
-
(1998)
J. Virol.
, vol.72
, pp. 7632-7637
-
-
Mammano, F.1
Petit, C.2
Clavel, F.3
-
16
-
-
17344367978
-
A preliminary evaluation of nelfinavir mesylate, an inhibitor of human immunodeficiency virus (HIV)-1 protease, to treat HIV infection
-
(1998)
J. Infect. Dis.
, vol.177
, pp. 1533-1540
-
-
Markowitz, M.1
Conant, M.2
Hurley, A.3
Schluger, R.4
Duran, M.5
Peterkin, J.6
Chapman, S.7
Patick, A.8
Hendricks, A.9
Yuen, G.J.10
Hoskins, W.11
Clendeninn, N.12
Ho, D.D.13
-
17
-
-
0028854676
-
Selection and analysis of human immunodeficiency virus type 1 variants with increased resistance to ABT-538, a novel protease inhibitor
-
(1995)
J. Virol.
, vol.69
, pp. 701-706
-
-
Markowitz, M.1
Mo, H.2
Kempf, D.J.3
Norbeck, D.W.4
Bhat, T.N.5
Erickson, J.W.6
Ho, D.D.7
-
18
-
-
0028806725
-
A preliminary study of ritonavir, an inhibitor of HIV-1 protease, to treat HIV-1 infection
-
(1995)
N. Engl. J. Med.
, vol.333
, pp. 1534-1539
-
-
Markowitz, M.1
Saag, M.2
Powderly, W.G.3
Hurley, A.M.4
Hsu, A.5
Valdes, J.M.6
Henry, D.7
Sattler, F.8
La Marca, A.9
Leonard, J.M.10
Ho, D.D.11
-
21
-
-
0032866277
-
An infectious DNA clone of HIV type 1 subtype C
-
(1999)
AIDS Res. Hum. Retroviruses
, vol.15
, pp. 1321-1324
-
-
Mochizuki, N.1
Otsuka, N.2
Matsuo, K.3
Shiino, T.4
Kojima, A.5
Kurata, T.6
Sakai, K.7
Yamamoto, N.8
Isomura, S.9
Dhole, T.N.10
Takebe, Y.11
Matsuda, M.12
Tatsumi, M.13
-
22
-
-
15444377672
-
Ordered accumulation of mutations in HIV protease confers resistance to ritonavir
-
(1996)
Nat. Med.
, vol.2
, pp. 760-766
-
-
Molla, A.1
Korneyeva, M.2
Gao, Q.3
Vasavanonda, S.4
Schipper, P.J.5
Mo, H.M.6
Markowitz, M.7
Chernyavskiy, T.8
Niu, P.9
Lyons, N.10
Hsu, A.11
Granneman, G.R.12
Ho, D.D.13
Boucher, C.A.14
Leonard, J.M.15
Norbeck, D.W.16
Kempf, D.J.17
-
23
-
-
0029092503
-
In vitro selection and characterization of human immunodeficiency virus type 1 (HIV-1) isolates with reduced sensitivity to hydroxyethylamino sulfonamide inhibitors of HIV-1 aspartyl protease
-
(1995)
J. Virol.
, vol.69
, pp. 5228-5235
-
-
Partaledis, J.A.1
Yamaguchi, K.2
Tisdale, M.3
Blair, E.E.4
Falcione, C.5
Maschera, B.6
Myers, R.E.7
Pazhanisamy, S.8
Futer, O.9
Cullinan, A.B.10
Stuver, C.M.11
Byrn, R.A.12
Livingston, D.J.13
-
24
-
-
0031692748
-
Genotypic and phenotypic characterization of human immunodeficiency virus type 1 variants isolated from patients treated with the protease inhibitor nelfinavir
-
(1998)
Antimicrob. Agents Chemother.
, vol.42
, pp. 2637-2644
-
-
Patick, A.K.1
Duran, M.2
Cao, Y.3
Shugarts, D.4
Keller, M.R.5
Mazabel, E.6
Knowles, M.7
Chapman, S.8
Kuritzkes, D.R.9
Markowitz, M.10
-
25
-
-
13344275873
-
Antiviral and resistance studies of AG1343, an orally bioavailable inhibitor of human immunodeficiency virus protease
-
Erratum, 40:1575
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 292-297
-
-
Patick, A.K.1
Mo, H.2
Markowitz, M.3
Appelt, K.4
Wu, B.5
Musick, L.6
Kalish, V.7
Kaldor, S.8
Reich, S.9
Ho, D.10
Webber, S.11
-
27
-
-
0029614884
-
Drug-resistance patterns of saquinavir and other HIV proteinase inhibitors
-
(1995)
AIDS
, vol.9
, Issue.SUPPL. 2
, pp. 27-32
-
-
Roberts, N.A.1
-
28
-
-
0025268321
-
Rational design of peptidebased HIV proteinase inhibitors
-
(1990)
Science
, vol.248
, pp. 358-361
-
-
Roberts, N.A.1
Martin, J.A.2
Kinchington, D.3
Broadhurst, A.V.4
Craig, J.C.5
Duncan, I.B.6
Galpin, S.A.7
Handa, B.K.8
Kay, J.9
Krohn, A.10
Lambert, R.W.11
Merrett, J.H.12
Mills, J.S.13
Parkes, K.E.B.14
Redshaw, S.15
Ritchie, A.J.16
Taylor, D.L.17
Thomas, G.J.18
Machin, P.J.19
-
29
-
-
0032750560
-
Two possible pathways for acquisition of mutations related to nelfinavir resistance
-
(1999)
Jpn. J. Infect. Dis.
, vol.52
, pp. 175-176
-
-
Sugiura, W.1
Oishi, T.2
Okano, A.3
Matsuda, M.4
Abum, H.5
Yamada, K.6
Koike, M.7
Taki, M.8
Ishikawa, M.9
Miura, T.10
Fukutake, K.11
Gouchi, K.12
Ajisawa, A.13
Iwamoto, A.14
Hanabusa, H.15
Mimaya, J.16
Takamatsu, J.17
Takata, N.18
Kakishita, E.19
Higasa, S.20
Kashiwagi, S.21
Shirahata, A.22
Nagai, Y.23
more..
-
30
-
-
0028222149
-
L-735,524: An orally bioavailable human immunodeficiency virus type 1 protease inhibitor
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 4096-4100
-
-
Vacca, J.P.1
Dorsey, B.D.2
Schleif, W.A.3
Levin, R.B.4
McDaniel, S.L.5
Darke, P.L.6
Zugay, J.7
Quintero, J.C.8
Blahy, O.M.9
Roth, E.10
Sardana, V.V.11
Schlabach, A.J.12
Graham, P.I.13
Condra, J.H.14
Gotlib, L.15
Holloway, M.K.16
Lin, J.17
Chen, I.-W.18
Vastag, K.19
Ostovic, D.20
Anderson, P.S.21
Emini, E.A.22
Huff, J.R.23
more..
-
33
-
-
0032771020
-
Drug resistance mutations can affect dimer stability of HIV-1 protease at neutral pH
-
(1999)
Protein Sci.
, vol.8
, pp. 1702-1707
-
-
Xie, D.1
Gulnik, S.2
Gustchina, E.3
Yu, B.4
Shao, W.5
Qoronfleh, W.6
Nathan, A.7
Erickson, J.W.8
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